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Literature summary extracted from

  • Wissner, J.L.; Ludwig, J.; Escobedo-Hinojosa, W.; Hauer, B.
    An enhanced toluene dioxygenase platform for the production of cis-1,2-dihydrocatechol in Escherichia coli BW25113 lacking glycerol dehydrogenase activity (2021), J. Biotechnol., 325, 380-388 .
    View publication on PubMed

Application

EC Number Application Comment Organism
1.14.12.11 synthesis Escherichia coli BW25113 DELTAgldA strain harboring pBAD18-TDO system is a suitable platform for the production of the valuable compound cis-1,2-dihydrocatechol at gram scale. The DHC scaffold finds extensive application in the production of a variety of fine chemicals and bioactive compounds Pseudomonas putida

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.12.11 expression into Escherichia coli BW25113 DELTAgldA. A strongly regulated toluene dioxygenase plasmid system for the dearomatizing cis-1,2-dihydroxylation of benzene is developed. Escherichia coli BW25113 DELTAgldA strain harboring pBAD18-TDO system is a suitable platform for the production of the valuable compound cis-1,2-dihydrocatechol (DHC) at gram scale Pseudomonas putida

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.6 Escherichia coli
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-
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1.1.1.6 Escherichia coli BW25113
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-
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1.14.12.11 Pseudomonas putida A5W4F2 AND A5W4F1 A5W4F2: toluene 2,3-dioxygenase subunit alpha, A5W4F1: toluene 2,3-dioxygenase subunit beta
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Synonyms

EC Number Synonyms Comment Organism
1.1.1.6 GldA
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 Escherichia coli
1.14.12.11 TDO
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 Pseudomonas putida

General Information

EC Number General Information Comment Organism
1.1.1.6 metabolism the native glycerol dehydrogenase in Escherichia coli is identified as the main responsible enzyme for catechol generation Escherichia coli
1.14.12.11 metabolism the native glycerol dehydrogenase in Escherichia coli is identified as the main responsible enzyme for catechol generation Pseudomonas putida