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Literature summary extracted from

  • Suyama, A.; Higuchi, Y.; Urushihara, M.; Maeda, Y.; Takegawa, K.
    Production of 3-hydroxypropionic acid via the malonyl-CoA pathway using recombinant fission yeast strains (2017), J. Biosci. Bioeng., 124, 392-399 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.75 expressed in Schizosaccharomyces pombe strain SPHP334 Chloroflexus aurantiacus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.75 cytoplasm
-
 Chloroflexus aurantiacus 5737
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.75 malonate semialdehyde + NADPH + H+ Chloroflexus aurantiacus
-
 3-hydroxypropionic acid + NADP+
-
 ?
1.2.1.75 malonyl-CoA + NADPH + H+ Chloroflexus aurantiacus
-
 malonate semialdehyde + CoA + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.75 Chloroflexus aurantiacus Q6QQP7
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.75 malonate semialdehyde + NADPH + H+
-
 Chloroflexus aurantiacus 3-hydroxypropionic acid + NADP+
-
 ?
1.2.1.75 malonyl-CoA + NADPH + H+
-
 Chloroflexus aurantiacus malonate semialdehyde + CoA + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.75 malonyl-CoA reductase
-
 Chloroflexus aurantiacus
1.2.1.75 MCR
-
 Chloroflexus aurantiacus

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.75 NADPH
-
 Chloroflexus aurantiacus