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Literature summary extracted from

  • Richter, A.S.; Banse, C.; Grimm, B.
    The GluTR-binding protein is the heme-binding factor for feedback control of glutamyl-tRNA reductase (2019), eLife, 8, e46300 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.70 expressed in Escherichia coli BL21 cells Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.70 plastid
-
 Arabidopsis thaliana 9536
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.70 L-glutamate 1-semialdehyde + NADP+ + tRNAGlu Arabidopsis thaliana
-
 L-glutamyl-tRNAGlu + NADPH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.70 Arabidopsis thaliana
-
 ecotype Col-0
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.70 Ni-NTA column chromatography and glutathione Sepharose column chromatography Arabidopsis thaliana

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.70 leaf
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.70 L-glutamate 1-semialdehyde + NADP+ + tRNAGlu
-
 Arabidopsis thaliana L-glutamyl-tRNAGlu + NADPH + H+
-
 ?
1.2.1.70 additional information binding of heme to the GluTR-binding protein (GBP) inhibits interaction of GBP with the N-terminal regulatory domain of isoform GluTR1, thus making it accessible to the Clp protease Arabidopsis thaliana ?
-
-

Synonyms

EC Number Synonyms Comment Organism
1.2.1.70 GluTR1 isoform Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.70 heme
-
 Arabidopsis thaliana