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Literature summary extracted from

  • Li, S.; Wang, H.; Jin, G.; Chen, Z.; Gu, G.
    Exploring the broad nucleotide triphosphate and sugar-1-phosphate specificity of thymidylyltransferase Cps23FL from Streptococcus pneumonia serotype 23F (2020), RSC Adv., 10, 30110-30114 .
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.24 dTTP + alpha-D-glucose 1-phosphate Streptococcus pneumoniae
-
 diphosphate + dTDP-alpha-D-glucose
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.24 Streptococcus pneumoniae
-
 serotype 23F
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.24 ATP + alpha-D-glucose 1-phosphate 13% yield with 0.006 mM enzyme, 78% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + ADP-alpha-D-glucose
-
 ?
2.7.7.24 dATP + alpha-D-glucosamine 1-phosphate 21% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dADP-alpha-D-glucosamine
-
 ?
2.7.7.24 dCTP + alpha-D-glucose 1-phosphate 35% yield with 0.006 mM enzyme, 87% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dCDP-alpha-D-glucose
-
 ?
2.7.7.24 dGTP + alpha-D-glucose 1-phosphate 53% yield with 0.006 mM enzyme, 89% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dGDP-alpha-D-glucose
-
 ?
2.7.7.24 dTTP + alpha-D-galactosamine 1-phosphate 5% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dTDP-alpha-D-galactosamine
-
 ?
2.7.7.24 dTTP + alpha-D-galactose 1-phosphate 91% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dTDP-alpha-D-galactose
-
 ?
2.7.7.24 dTTP + alpha-D-glucosamine 1-phosphate 71% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dTDP-alpha-D-glucosamine
-
 ?
2.7.7.24 dTTP + alpha-D-glucose 1-phosphate
-
 Streptococcus pneumoniae diphosphate + dTDP-alpha-D-glucose
-
 ?
2.7.7.24 dTTP + alpha-D-glucose 1-phosphate 86% yield with 0.006 mM enzyme, 93% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dTDP-alpha-D-glucose
-
 ?
2.7.7.24 dTTP + alpha-D-mannose 1-phosphate 88% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dTDP-alpha-D-mannose
-
 ?
2.7.7.24 dUTP + alpha-D-galactose 1-phosphate 83% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dUDP-alpha-D-galactose
-
 ?
2.7.7.24 dUTP + alpha-D-glucose 1-phosphate 88% yield with 0.006 mM enzyme, 95% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dUDP-alpha-D-glucose
-
 ?
2.7.7.24 GTP + alpha-D-glucose 1-phosphate no product yield with 0.006 mM enzyme, 91% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + GDP-alpha-D-glucose
-
 ?
2.7.7.24 GTP + alpha-D-mannose 1-phosphate 13% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + GDP-alpha-D-mannose
-
 ?
2.7.7.24 additional information no activity with alpha-D-galacturonic acid 1-phosphate Streptococcus pneumoniae ?
-
-
2.7.7.24 UTP + alpha-D-galactose 1-phosphate 86% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + UDP-alpha-D-galactose
-
 ?
2.7.7.24 UTP + alpha-D-glucosamine 1-phosphate 12% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + UDP-alpha-D-glucosamine
-
 ?
2.7.7.24 UTP + alpha-D-glucose 1-phosphate 40% yield with 0.006 mM enzyme, 94% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + UDP-alpha-D-glucose
-
 ?
2.7.7.24 UTP + alpha-D-mannose 1-phosphate 78% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + UDP-alpha-D-mannose
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.7.24 Cps23FL
-
 Streptococcus pneumoniae
2.7.7.24 glucose-1-phosphate thymidylyltransferase
-
 Streptococcus pneumoniae