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Literature summary extracted from
- Discovery and biochemical characterization of UDP-Glucose dehydrogenase from Akkermansia muciniphila (2017), Protein Pept. Lett., 24, 735-741 .
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.1.1.22 | expression in Escherichia coli | Akkermansia muciniphila |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.22 | additional information | enzyme is active in the absence of metal ions | Akkermansia muciniphila | |
| 1.1.1.22 | Zn2+ | the presence of Zn2+ ions markedly stimulates catalytic activity | Akkermansia muciniphila |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.22 | Akkermansia muciniphila | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.22 | UDP-alpha-D-glucose + 2 NAD+ + H2O | - |
Akkermansia muciniphila | UDP-alpha-D-glucuronate + 2 NADH + 2 H+ | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.22 | 37 | - |
- |
Akkermansia muciniphila |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.22 | 9 | - |
- |
Akkermansia muciniphila |
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Release 2023.1 (January 2023)
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