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Literature summary extracted from

  • Yang, Y.B.; Yin, J.; Huang, L.Q.; Li, J.; Chen, D.K.; Yao, N.
    Salt enhances disease resistance and suppresses cell death in ceramide kinase mutants (2019), Plant Physiol., 181, 319-331 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
2.7.1.138 additional information generation of an Arabidopsis thaliana cell-death mutant, accelerated cell death5 (acd5), which accumulates ceramides and exhibits spontaneous cell death late in development. NaCl enhances disease resistance and suppresses cell death in ceramide kinase mutants. The effect of NaCl is partly dependent on the antagonistic interaction between endogenous abscisic acid (ABA) and salicylic acid (SA). The intact ABA pathway may not be required for this effect. The response of the acd5 mutant to abiotic stress shows that the mutants do not have the cell-death phenotype. 300 mM NaCl suppresses the cell-death phenotype of the acd5 mutant without inhibiting plant growth. NaCl treatment inhibits sphingolipid accumulation in the acd5 mutant and alters the endogenous levels of SA and ABA Arabidopsis thaliana

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.138 Mg2+ required Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.138 ATP + ceramide Arabidopsis thaliana
-
 ADP + ceramide 1-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.138 Arabidopsis thaliana Q6USK2
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.138 ATP + ceramide
-
 Arabidopsis thaliana ADP + ceramide 1-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.138 CERK
-
 Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.138 ATP
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
2.7.1.138 malfunction Arabidopsis thaliana cell-death mutant, accelerated cell death5 (acd5), which accumulates ceramides and exhibits spontaneous cell death late in development. NaCl enhances disease resistance and suppresses cell death in ceramide kinase mutants partly via a mechanism that depends on abscisic acid (ABA) and salicylic acid (SA) antagonistic interaction, and enhances disease resistance independent of pattern-triggered immune responses. 300 mM NaCl suppresses the cell-death phenotype of the acd5 mutant without inhibiting plant growth Arabidopsis thaliana