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Literature summary extracted from

  • Yang, Q.Q.; Yu, W.H.; Wu, H.Y.; Zhang, C.Q.; Sun, S.S.; Liu, Q.Q.
    Lysine biofortification in rice by modulating feedback inhibition of aspartate kinase and dihydrodipicolinate synthase (2021), Plant Biotechnol. J., 19, 490-501 .
    View publication on PubMed

Application

EC Number Application Comment Organism
2.7.2.4 nutrition enzyme mutants may be used to improve the nutritional quality of rice and other cereal grains Oryza sativa Japonica Group

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.2.4 mutant enzymes are expressed in Escherichia coli BL21 cells Oryza sativa Japonica Group

Protein Variants

EC Number Protein Variants Comment Organism
2.7.2.4 S449L transgenic plants expressing the mutant enzyme show a 6.6fold increased free lysine content Oryza sativa Japonica Group
2.7.2.4 T448M transgenic plants expressing the mutant enzyme show about 2fold increased free lysine content Oryza sativa Japonica Group

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.2.4 L-lysine
-
 Oryza sativa Japonica Group
2.7.2.4 L-threonine
-
 Oryza sativa Japonica Group
2.7.2.4 additional information insensitive to S-(2-aminoethyl)-L-cysteine at concentrations up to 12 mM Oryza sativa Japonica Group

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.2.4 ATP + L-aspartate Oryza sativa Japonica Group
-
 ADP + 4-phospho-L-aspartate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.2.4 Oryza sativa Japonica Group Q5JK18
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.2.4 ATP + L-aspartate
-
 Oryza sativa Japonica Group ADP + 4-phospho-L-aspartate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.2.4 lysC
-
 Oryza sativa Japonica Group