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Literature summary extracted from

  • Zhao, X.; Dai, Q.; Jia, R.; Zhu, D.; Liu, M.; Wang, M.; Chen, S.; Sun, K.; Yang, Q.; Wu, Y.; Cheng, A.
    Two novel Salmonella bivalent vaccines confer dual protection against two Salmonella serovars in mice (2017), Front. Cell. Infect. Microbiol., 7, 391 .
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.3.1.303 medicine construction of bivalent vaccines for preventing both Salmonella typhimurium and Salmonella newport infections by using the aspartate semialdehyde dehydrogenase-based balanced-lethal vector-host system. The constructed plasmid pCZ11 carrying a subset of the Salmonella newport O-antigen gene cluster including the wzx-wbaR-wbaL-wbaQ-wzy-wbaW-wbaZ genes is introduced into Salmonella typhimurium. Upon deletion of the crp gene for attenuation purposes, BALB/c mice are orally immunized with the strains. Compared with a mock immunization, immunization with the vaccine strains induces significant serum IgG responses against both Salmonella typhimurium and Salmonella newport lipopolysaccharide Salmonella enterica subsp. enterica serovar Newport
2.4.1.379 medicine construction of bivalent vaccines for preventing both Salmonella typhimurium and Salmonella newport infections by using the aspartate semialdehyde dehydrogenase-based balanced-lethal vector-host system. The constructed plasmid pCZ11 carrying a subset of the Salmonella newport O-antigen gene cluster including the wzx-wbaR-wbaL-wbaQ-wzy-wbaW-wbaZ genes is introduced into Salmonella typhimurium. Upon deletion of the crp gene for attenuation purposes, BALB/c mice are orally immunized with the strains. Compared with a mock immunization, immunization with the vaccine strains induces significant serum IgG responses against both Salmonella typhimurium and Salmonella newport lipopolysaccharide Salmonella enterica subsp. enterica serovar Newport
2.4.1.381 medicine construction of bivalent vaccines for preventing both Salmonella typhimurium and Salmonella newport infections by using the aspartate semialdehyde dehydrogenase-based balanced-lethal vector-host system. The constructed plasmid pCZ11 carrying a subset of the Salmonella newport O-antigen gene cluster including the wzx-wbaR-wbaL-wbaQ-wzy-wbaW-wbaZ genes is introduced into Salmonella typhimurium. Upon deletion of the crp gene for attenuation purposes, BALB/c mice are orally immunized with the strains. Compared with a mock immunization, immunization with the vaccine strains induces significant serum IgG responses against both Salmonella typhimurium and Salmonella newport lipopolysaccharide Salmonella enterica subsp. enterica serovar Newport
2.4.1.382 medicine construction of bivalent vaccines for preventing both Salmonella typhimurium and Salmonella newport infections by using the aspartate semialdehyde dehydrogenase-based balanced-lethal vector-host system. The constructed plasmid pCZ11 carrying a subset of the Salmonella newport O-antigen gene cluster including the wzx-wbaR-wbaL-wbaQ-wzy-wbaW-wbaZ genes is introduced into Salmonella typhimurium. Upon deletion of the crp gene for attenuation purposes, BALB/c mice are orally immunized with the strains. Compared with a mock immunization, immunization with the vaccine strains induces significant serum IgG responses against both Salmonella typhimurium and Salmonella newport lipopolysaccharide Salmonella enterica subsp. enterica serovar Newport

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.303 Salmonella enterica subsp. enterica serovar Newport
-
-
-
2.4.1.379 Salmonella enterica subsp. enterica serovar Newport
-
-
-
2.4.1.381 Salmonella enterica subsp. enterica serovar Newport
-
-
-
2.4.1.382 Salmonella enterica subsp. enterica serovar Newport
-
-
-

Synonyms

EC Number Synonyms Comment Organism
2.3.1.303 wbaL
-
 Salmonella enterica subsp. enterica serovar Newport
2.4.1.379 wbaL
-
 Salmonella enterica subsp. enterica serovar Newport
2.4.1.381 wbaQ
-
 Salmonella enterica subsp. enterica serovar Newport
2.4.1.382 wbaR
-
 Salmonella enterica subsp. enterica serovar Newport