Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Ikeda, S.; Kawahara-Miki, R.; Iwata, H.; Sugimoto, M.; Kume, S.
    Role of methionine adenosyltransferase 2A in bovine preimplantation development and its associated genomic regions (2017), Sci. Rep., 7, 3800 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.6 fluorinated N,N-dialkylaminostilbene-5 i.e. FIDAS Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.6 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.6 embryo preimplantation embryo Bos taurus
-
2.5.1.6 oocyte
-
 Bos taurus
-

Synonyms

EC Number Synonyms Comment Organism
2.5.1.6 MAT2A
-
 Bos taurus
2.5.1.6 methionine adenosyltransferase 2A
-
 Bos taurus

Expression

EC Number Organism Comment Expression
2.5.1.6 Bos taurus immunofluorescence analysis of bovine oocytes and preimplantation embryos revealed the consistent expression of MAT2A (the catalytic subunit of the ubiquitously expressed-type of MAT isozyme) during this period up

General Information

EC Number General Information Comment Organism
2.5.1.6 malfunction addition of the methionine adenosyltransferase (MAT2A) inhibitor FIDAS to the culture media of bovine preimplantation embryos reduces their blastocyst development Bos taurus
2.5.1.6 metabolism the enzyme is involved in folate-mediated one-carbon metabolism which is essential for preimplantation embryos in terms of both short-term periconceptional development and long-term phenotypic programming beyond the periconceptional period. Particular importance of the enzyme (MAT2A) in successful blastocyst development. Critical involvement of the enzyme (MAT2A) in the periconceptional period in life-long programming of health and disease as well as successful preimplantation development Bos taurus