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Literature summary extracted from

  • Shu, B.; Gong, P.
    The uncoupling of catalysis and translocation in the viral RNA-dependent RNA polymerase (2017), RNA Biol., 14, 1314-1319 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.48 nucleoside triphosphate + RNAn Enterovirus A71
-
 diphosphate + RNAn+1
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.48 Enterovirus A71 E5RPG2
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.48 nucleoside triphosphate + RNAn
-
 Enterovirus A71 diphosphate + RNAn+1
-
 ?
2.7.7.48 nucleoside triphosphate + RNAn catalysis and translocation are uncoupled in the viral RNA-dependent RNA polymerase. A motif B loop may assist the movement of the template strand in late stages of transcription Enterovirus A71 diphosphate + RNAn+1
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.7.48 RDRP
-
 Enterovirus A71
2.7.7.48 RNA-dependent RNA polymerase
-
 Enterovirus A71