Literature summary extracted from

Hanson, A.; Amthor, J.; Sun, J.; Niehaus, T.; Gregory, J.I.; Bruner, S.; Ding, Y.
Redesigning thiamin synthesis Prospects and potential payoffs (2018), Plant Sci., 273, 92-99 .

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
2.4.2.60	chloroplast	-	Hordeum vulgare	9507	-
2.4.2.60	chloroplast	-	Arabidopsis thaliana	9507	-

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.4.2.60	NAD+ + glycine + [ADP-thiazole synthase]-L-cysteine	Hordeum vulgare	-	nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + [ADP-thiazole synthase]-dehydroalanine + 3 H2O	-	?
2.4.2.60	NAD+ + glycine + [ADP-thiazole synthase]-L-cysteine	Arabidopsis thaliana	-	nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + [ADP-thiazole synthase]-dehydroalanine + 3 H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.2.60	Arabidopsis thaliana	-	-	-
2.4.2.60	Hordeum vulgare	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.4.2.60	leaf	-	Hordeum vulgare	-
2.4.2.60	leaf	-	Arabidopsis thaliana	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.2.60	NAD+ + glycine + [ADP-thiazole synthase]-L-cysteine	-	Hordeum vulgare	nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + [ADP-thiazole synthase]-dehydroalanine + 3 H2O	-	?
2.4.2.60	NAD+ + glycine + [ADP-thiazole synthase]-L-cysteine	-	Arabidopsis thaliana	nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + [ADP-thiazole synthase]-dehydroalanine + 3 H2O	-	?

Subunits

EC Number	Subunits	Comment	Organism
2.4.2.60	?	x * 37130, calculated from amino acid sequence	Hordeum vulgare
2.4.2.60	?	x * 36664, calculated from amino acid sequence	Arabidopsis thaliana

Synonyms

EC Number	Synonyms	Comment	Organism
2.4.2.60	Thi4	-	Hordeum vulgare
2.4.2.60	Thi4	-	Arabidopsis thaliana

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Release 2023.1 (January 2023)