Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Xiao, W.; Hu, S.; Zhou, X.; Yao, R.; Luo, J.; Yuan, C.; Chang, H.; Zhang, C.; Huang, J.; Li, J.; Liu, S.; Li, M.; Guo, X.
    A glucuronokinase gene in Arabidopsis, AtGlcAK, is involved in drought tolerance by modulating sugar metabolism (2017), Plant Mol. Biol. Rep., 35, 298-311 .
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.43 gene GlcAK, phylogenetic analysis, quantitative and semi-quantitative RT-PCR enzyme expression analysis Arabidopsis thaliana
2.7.1.43 gene GlcAK2, phylogenetic analysis Arabidopsis thaliana

Protein Variants

EC Number Protein Variants Comment Organism
2.7.1.43 additional information identification of two T-DNA insertion homozygous mutants of AtGlcAK, atglcak-1 and atglcak-2. AtGlcAK mutants display hypersensitivity to abscisic acid (ABA) and reduced root development under water stress, rendering the plants more susceptible to drought stress. The atglcak mutants display shorter primary root and less lateral roots under osmotic stress. Loss-of-function of AtGlcAK Affects the expression of ABA-induced and sugar-metabolic genes. Phenotypes of atglcak-1 and atglcak-2, overview Arabidopsis thaliana

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.43 Mg2+ required Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.43 ATP + D-glucuronate Arabidopsis thaliana
-
 ADP + 1-phospho-alpha-D-glucuronate
-
 ?
2.7.1.43 ATP + D-glucuronate Arabidopsis thaliana Col-0
-
 ADP + 1-phospho-alpha-D-glucuronate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.43 Arabidopsis thaliana Q93ZC9
-
-
2.7.1.43 Arabidopsis thaliana Q9LY82
-
-
2.7.1.43 Arabidopsis thaliana Col-0 Q93ZC9
-
-
2.7.1.43 Arabidopsis thaliana Col-0 Q9LY82
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.43 flower
-
 Arabidopsis thaliana
-
2.7.1.43 flower AtGlcAK is highly expressed in flowers Arabidopsis thaliana
-
2.7.1.43 additional information the transcripts abundance of isozyme AtGALK2 is much less than that of isozyme AtGlcAK in all analyzed tissues. Except for the transcripts in seed, the expression abundance of AtGALK2 in the rest of detected tissues is always less than half the level of AtGlcAK Arabidopsis thaliana
-
2.7.1.43 root
-
 Arabidopsis thaliana
-
2.7.1.43 root AtGlcAK is highly expressed in roots Arabidopsis thaliana
-
2.7.1.43 rosette leaf
-
 Arabidopsis thaliana
-
2.7.1.43 seed
-
 Arabidopsis thaliana
-
2.7.1.43 seedling
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.43 ATP + D-glucuronate
-
 Arabidopsis thaliana ADP + 1-phospho-alpha-D-glucuronate
-
 ?
2.7.1.43 ATP + D-glucuronate
-
 Arabidopsis thaliana Col-0 ADP + 1-phospho-alpha-D-glucuronate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.43 AtGlcAK
-
 Arabidopsis thaliana
2.7.1.43 AtGlcAK2
-
 Arabidopsis thaliana
2.7.1.43 GlcAK
-
 Arabidopsis thaliana
2.7.1.43 GlcAK2
-
 Arabidopsis thaliana
2.7.1.43 glucuronokinase 1
-
 Arabidopsis thaliana
2.7.1.43 glucuronokinase 2
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
2.7.1.43 malfunction there is reduced primary root elongation and lateral root formation in atglcak mutants under osmotic stress. The atglcak mutants display enhanced stomatal opening in response to abscisic acid (ABA), elevated water loss, and impaired drought tolerance. Under water stress, the accumulation of reducing and soluble sugars is reduced in atglcak mutants, and the metabolism of glucose and sucrose is affected by the synthetic pathway of UDP-GlcA. Furthermore, a reduced level of starch in atglcak mutants is observed under normal conditions Arabidopsis thaliana
2.7.1.43 physiological function isozyme glucuronokinase 1 gene, AtGlcAK, in Arabidopsis thaliana is involved in drought tolerance by modulating sugar metabolism Arabidopsis thaliana
2.7.1.43 physiological function isozyme glucuronokinase 1 gene, AtGlcAK, in Arabidopsis thaliana is involved in drought tolerance by modulating sugar metabolism and in abscisic acid-mediated stomata movement. AtGlcAK is implicated in carbohydrate metabolism and regulates the synthesis of glucose and sucrose which served as signaling molecules to regulate gene expressions, development and adaption to environmental stress factors Arabidopsis thaliana