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Literature summary extracted from

  • Pattanaik, B.; Englund, E.; Nolte, N.; Lindberg, P.
    Introduction of a green algal squalene synthase enhances squalene accumulation in a strain of Synechocystis sp. PCC 6803 (2020), Metab. Eng. Commun., 10, e00125 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.21 expressed in Synechocystis sp. PCC 6803 Botryococcus braunii
2.5.1.21 heterologous expression of a squalene synthase from Botryocuccus braunii can increase squalene accumulation in a DELTAshc strain of Synechocystis Botryococcus braunii

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.5.1.21 Ni2+ the enzyme is induced by the addition of 0.0025 mM Ni2+ Botryococcus braunii

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.21 2 farnesyl diphosphate + NADPH + H+ Botryococcus braunii
-
squalene + 2 diphosphate + NADP+
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.21 Botryococcus braunii Q9SDW9
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.21 2 farnesyl diphosphate + NADPH + H+
-
Botryococcus braunii squalene + 2 diphosphate + NADP+
-
?

Subunits

EC Number Subunits Comment Organism
2.5.1.21 ? x * 45000, FLAG-tagged enzyme, SDS-PAGE Botryococcus braunii

Synonyms

EC Number Synonyms Comment Organism
2.5.1.21 BSS
-
Botryococcus braunii

Cofactor

EC Number Cofactor Comment Organism Structure
2.5.1.21 NADPH
-
Botryococcus braunii