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Literature summary extracted from

  • Hu, X.; Zhang, Y.Q.; Lee, O.W.; Liu, L.; Tang, M.; Lai, K.; Boxer, M.B.; Hall, M.D.; Shen, M.
    Discovery of novel inhibitors of human galactokinase by virtual screening (2019), J. Comput. Aided Mol. Des., 33, 405-417 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.6 additional information discovery of novel inhibitors of human galactokinase by high-throughput structure-based virtual screening Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.6 ATP + alpha-D-galactose Homo sapiens
-
 ADP + alpha-D-galactose 1-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.6 Homo sapiens P51570
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.6 ATP + alpha-D-galactose
-
 Homo sapiens ADP + alpha-D-galactose 1-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.6 GALK1
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
2.7.1.6 drug target a pharmacological inhibitor of galactokinase is hypothesized to be therapeutic strategy for treating galactosemia by reducing production of alpha-D-galactose 1-phosphate Homo sapiens