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Literature summary extracted from
- Regulation of the heme A biosynthetic pathway differential regulation of heme A synthase and heme O synthase in Saccharomyces cerevisiae (2009), J. Biol. Chem., 284, 839-847 .
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.17.99.9 | inner mitochondrial membrane | - |
Saccharomyces cerevisiae | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.17.99.9 | Saccharomyces cerevisiae | - |
- |
- |
| 1.17.99.9 | Saccharomyces cerevisiae W303a | - |
- |
- |
Oxidation Stability
| EC Number | Oxidation Stability | Organism |
|---|---|---|
| 1.17.99.9 | the stability of Cox15 is not decreased in the absence of cytochrome c oxidase | Saccharomyces cerevisiae |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.17.99.9 | COX15 | - |
Saccharomyces cerevisiae |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 1.17.99.9 | Saccharomyces cerevisiae | transcription of COX15 is positively regulated by by Hap1, a transcription factor whose activity is positively controlled by intracellular heme concentration. While COX15 mRNA levels increase with increasing intracellular heme levels in the presence of Hap1, the mRNA levels of COX15 are depressed and independent of intracellular heme levels in the absence of Hap1 | up |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 1.17.99.9 | metabolism | the enzyme is required for heme A biosynthesis | Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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