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Literature summary extracted from

  • Li, B.; Meng, J.; Li, L.; Liu, S.; Wang, T.; Zhang, G.
    Identification and functional characterization of the glycogen synthesis related gene glycogenin in Pacific oysters (Crassostrea gigas) (2017), J. Agric. Food Chem., 65, 7764-7773 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.186 gene CGI_10023521, DNA and amino acid sequence determination and analysis, the Pacific oyster encodes three isozymes of glycogenin: CgGN-alpha, CgGN-beta, and CgGN-gamma, genetic structure and sequence comparisons, phylogenetic tree. The isolated three CgGN isoforms contain alternative exon regions. PCR-based quantitative expression analysis. Recombinant expression of FLAG-tagged enzymes in HEK-293T cells, recombinant expression of EGFP-tagged enzyme from pEGFP-N1-CgGN in HeLa cells Crassostrea gigas

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.186 UDP-alpha-D-glucose + glycogenin Crassostrea gigas
-
 UDP + alpha-D-glucosylglycogenin
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.186 Crassostrea gigas K1R9A7
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.186 adductor CgGN mRNA expression pattern in adductor muscle during different months, overview. CgGN mRNA expression is closely related to glycogen content and CgGS expression Crassostrea gigas
-
2.4.1.186 gonad CgGN mRNA expression patterns in gonadal tissue during different months, overview Crassostrea gigas
-
2.4.1.186 additional information seasonal distribution of CgGN transcripts in adductor muscle and gonad, overview Crassostrea gigas
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.186 UDP-alpha-D-glucose + glycogenin
-
 Crassostrea gigas UDP + alpha-D-glucosylglycogenin
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.1.186 ? x * 60300, about, sequence calculation Crassostrea gigas

Synonyms

EC Number Synonyms Comment Organism
2.4.1.186 CgGN
-
 Crassostrea gigas
2.4.1.186 CgGN-alpha
-
 Crassostrea gigas
2.4.1.186 CgGN-beta
-
 Crassostrea gigas
2.4.1.186 CgGN-gamma
-
 Crassostrea gigas
2.4.1.186 glycogenin
-
 Crassostrea gigas
2.4.1.186 glycogenin-1
-
 Crassostrea gigas

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.4.1.186 Crassostrea gigas sequence calculation
-
 5.05

General Information

EC Number General Information Comment Organism
2.4.1.186 evolution the Pacific oyster has three isozymes of glycogenin: CgGN-alpha, CgGN-beta, and CgGN-gamma. Functional motif architecture analysis shows that CgGN is structurally similar to mammalian glycogenin-1. All three CgGN isoforms contain the key domain of glycosyltransferase and the C-terminal domain Crassostrea gigas
2.4.1.186 physiological function high glycogen levels in the Pacific oyster (Crassostrea gigas) contribute to its flavor, quality, and hardiness. Glycogenin (CgGN) is the priming glucosyltransferase that initiates glycogen biosynthesis. mRNA expression is closely related to glycogen content and CgGS expression Crassostrea gigas