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Literature summary extracted from

  • Farkas, W.; Bruce Jacobson, K.
    tRNA-guanine transglycosylase and guanine-accepting transfer RNAs of Drosophila melanogaster (1980), Insect Biochem., 10, 183-188 .
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.2.64 guanine34 in tRNA + queuine Drosophila melanogaster
-
 queuine34 in tRNA + guanine
-
 ?
2.4.2.64 guanine34 in tRNA + queuine Oryctolagus cuniculus
-
 queuine34 in tRNA + guanine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.64 Drosophila melanogaster
-
-
-
2.4.2.64 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.64 larva the enzyme activity is present in third instar larvae and adult flies but is absent in late pupae Drosophila melanogaster
-
2.4.2.64 pupa the enzyme activity is present in third instar larvae and adult flies but is absent in late pupae Drosophila melanogaster
-
2.4.2.64 reticulocyte
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.64 guanine34 in tRNA + queuine
-
 Drosophila melanogaster queuine34 in tRNA + guanine
-
 ?
2.4.2.64 guanine34 in tRNA + queuine
-
 Oryctolagus cuniculus queuine34 in tRNA + guanine
-
 ?
2.4.2.64 guanine34 in tRNA + queuine the enzyme replaces a guanine in the anticodon of tRNAs for Asn, Asp, His, and Tyr. In the absence of queuine, this enzyme catalyzes an exchange between free guanine with guanine Drosophila melanogaster queuine34 in tRNA + guanine
-
 ?
2.4.2.64 guanine34 in tRNA + queuine the enzyme replaces a guanine in the anticodon of tRNAs for Asn, Asp, His, and Tyr. In the absence of queuine, this enzyme catalyzes an exchange between free guanine with guanine Oryctolagus cuniculus queuine34 in tRNA + guanine
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.2.64 7.4
-
-
 Drosophila melanogaster

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.4.2.64 6.2 7.8 pH 6.2: about 50% of maximal activity, pH 7.8: about 50% of maximal activity Drosophila melanogaster