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Literature summary extracted from

  • Du, T.; Ouyang, H.; Voglmeir, J.; Wilson, I.B.H.; Jin, C.
    Aspergillus fumigatus Mnn9 is responsible for mannan synthesis and required for covalent linkage of mannoprotein to the cell wall (2019), Fungal Genet. Biol., 128, 20-28 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.232 Aspergillus fumigatus Q4WIL2 i.e. Aspergillus fumigatus strain YJ-407
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2.4.1.232 Aspergillus fumigatus ATCC MYA-4609 Q4WIL2 i.e. Aspergillus fumigatus strain YJ-407
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Synonyms

EC Number Synonyms Comment Organism
2.4.1.232 AFUA_2G01450 genme name Aspergillus fumigatus
2.4.1.232 Mnn9
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 Aspergillus fumigatus

General Information

EC Number General Information Comment Organism
2.4.1.232 malfunction deletion of the mnn9 gene results in an increased sensitivity to calcofluor white, Congo red, or hygromycin B as well as in reduced cell wall components and abnormal polarity. Although there is no major effect on N-glycan synthesis, covalently-linked cell wall mannoprotein Mp1 is significantly reduced in the mutant Aspergillus fumigatus
2.4.1.232 physiological function Mnn9 is required for mannan and mannoprotein biosynthesis. The enzyme is essential for cell wall integrity, morphogenesis, and proper localization of cell wall mannoprotein Aspergillus fumigatus