Literature summary extracted from

Eby, J.M.; Barse, L.; Henning, S.W.; Rabelink, M.J.; Klarquist, J.; Gilbert, E.R.; Hammer, A.M.; Fernandez, M.F.; Yung, N.; Khan, S.; Miller, H.G.; Kessler, E.R.; Garrett-Mayer, E.; Dilling, D.F.; Hoeben, R.C.; Le Poole, I.C.
alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 can support immune responses toward tumors overexpressing ganglioside D3 in mice (2017), Cancer Immunol. Immunother., 66, 63-75 .

Application

EC Number	Application	Comment	Organism
2.4.3.8	medicine	adenoviral enzyme can slow the growth of ganglioside GD3 expressing tumors in patients	Mus musculus

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.4.3.8	expressed in Escherichia coli TOP10 cells and HEK-293 cells	Mus musculus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.4.3.8	CMP-N-acetylneuraminate + ganglioside GM3	Mus musculus	-	CMP + ganglioside GD3	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.3.8	Mus musculus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.4.3.8	natural killer T cell	-	Mus musculus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.3.8	CMP-N-acetylneuraminate + ganglioside GM3	-	Mus musculus	CMP + ganglioside GD3	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.4.3.8	alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	-	Mus musculus
2.4.3.8	GD3 synthase	-	Mus musculus
2.4.3.8	SIAT8	-	Mus musculus

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Release 2023.1 (January 2023)