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Literature summary extracted from

  • Li, W.; Zhang, F.; Wu, R.; Jia, L.; Li, G.; Guo, Y.; Liu, C.; Wang, G.
    A novel N-methyltransferase in Arabidopsis appears to feed a conserved pathway for nicotinate detoxification among land plants and is associated with lignin biosynthesis (2017), Plant Physiol., 174, 1492-1504 .
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.1.1.7 0.0387
-
 nicotinate pH 7.5, 28°C Arabidopsis thaliana

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.7 Arabidopsis thaliana Q9SCP7
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.7 additional information product N-methylnicotinate accumulates predominantly in inflorescence tissues Arabidopsis thaliana
-
2.1.1.7 silique
-
 Arabidopsis thaliana
-
2.1.1.7 stem
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.7 S-adenosyl-L-methionine + nicotinate
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + N-methylnicotinate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.7 At3g53140
-
 Arabidopsis thaliana
2.1.1.7 NANMT
-
 Arabidopsis thaliana
2.1.1.7 T4D2.70
-
 Arabidopsis thaliana

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.1.1.7 3.52
-
 nicotinate pH 7.5, 28°C Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
2.1.1.7 physiological function homozygous mutant lines show marked reductions in N-methylnicotinate accumulation in inflorescence tissues, whereas the levels of nicotinate, glucosylated nicotinate, nicotinate mononucleotide, and NAD are increased. Overexpressing lines have higher N-methylnicotinate content and lower nicotinate, glucosylated nicotinate, nicotinate mononucleotide, and NAD contents Arabidopsis thaliana

kcat/KM [mM/s]

EC Number kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
2.1.1.7 91
-
 nicotinate pH 7.5, 28°C Arabidopsis thaliana