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Literature summary extracted from

  • Park, J.H.; Kang, C.H.; Nawkar, G.M.; Lee, E.S.; Paeng, S.K.; Chae, H.B.; Chi, Y.H.; Kim, W.Y.; Yun, D.J.; Lee, S.Y.
    EMR, a cytosolic-abundant ring finger E3 ligase, mediates ER-associated protein degradation in Arabidopsis (2018), New Phytol., 220, 163-177 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.2.27 expression in Escherichia coli Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.2.27 cytosol
-
 Arabidopsis thaliana 5829
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.27 Arabidopsis thaliana A0A178UZG1 isoform EMR
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.27 [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [MLO12-Myc]-L-lysine
-
 Arabidopsis thaliana [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor MLO12-Myc]-N6-ubiquitinyl-L-lysine
-
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Synonyms

EC Number Synonyms Comment Organism
2.3.2.27 At4g26400
-
 Arabidopsis thaliana
2.3.2.27 EMR
-
 Arabidopsis thaliana
2.3.2.27 ERAD-mediating RING finger protein
-
 Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
2.3.2.27 Arabidopsis thaliana EMR is significantly upregulated under endoplasmic reticulum stress conditions up

General Information

EC Number General Information Comment Organism
2.3.2.27 physiological function tobacco leaf-produced EMR mediates mildew resistance locus O-12 degradation in a proteasome-dependent manner. EMR forms a complex with ubiquitin-conjugating enzyme UBC32. Mutation of EMR and RNAi increase the tolerance of plants to endoplasmic reticulum stress. EMR RNAi in a brassinosteroid signaling mutant protein background, leads to partial recovery of the brassinosteroid insensitive phenotypes as compared with the original mutant plants and increased ER stress tolerance Arabidopsis thaliana