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Literature summary extracted from

  • Thammahong, A.; Caffrey-Card, A.K.; Dhingra, S.; Obar, J.J.; Cramer, R.A.
    Aspergillus fumigatus trehalose-regulatory subunit homolog moonlights to mediate cell wall homeostasis through modulation of chitin synthase activity (2017), mBio, 8, e00056-17 .
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.16 additional information TslA alters CsmA localization and, consequently, its chitin synthase activity Aspergillus fumigatus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.16 UDP-N-acetyl-alpha-D-glucosamine + [(1->4)-N-acetyl-beta-D-glucosaminyl]n Aspergillus fumigatus
-
 UDP + [(1->4)-N-acetyl-beta-D-glucosaminyl]n+1
-
 ?
2.4.1.16 UDP-N-acetyl-alpha-D-glucosamine + [(1->4)-N-acetyl-beta-D-glucosaminyl]n Aspergillus fumigatus CEA17
-
 UDP + [(1->4)-N-acetyl-beta-D-glucosaminyl]n+1
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.16 Aspergillus fumigatus
-
-
-
2.4.1.16 Aspergillus fumigatus CEA17
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.16 mycelium
-
 Aspergillus fumigatus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.16 UDP-N-acetyl-alpha-D-glucosamine + [(1->4)-N-acetyl-beta-D-glucosaminyl]n
-
 Aspergillus fumigatus UDP + [(1->4)-N-acetyl-beta-D-glucosaminyl]n+1
-
 ?
2.4.1.16 UDP-N-acetyl-alpha-D-glucosamine + [(1->4)-N-acetyl-beta-D-glucosaminyl]n
-
 Aspergillus fumigatus CEA17 UDP + [(1->4)-N-acetyl-beta-D-glucosaminyl]n+1
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.16 CsmA
-
 Aspergillus fumigatus