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Literature summary extracted from

  • Kim, H.J.; Qiao, Q.; Toop, H.D.; Morris, J.C.; Don, A.S.
    A fluorescent assay for ceramide synthase activity (2012), J. Lipid Res., 53, 1701-1707 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.299 FTY720 competitive inhibitor Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.299 endoplasmic reticulum
-
 Homo sapiens 5783
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.1.299 Mg2+ 2 mM used in assay conditions Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.299 stearoyl-CoA + NBD-labelled sphinganine Homo sapiens NBD-labelled sphinganine is (2S,3R)-2-amino-18-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)octadecane-1,3-diol N-(stearoyl)-sphinganine + CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.299 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.299 brain highest expression Homo sapiens
-
2.3.1.299 HEK-293 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.299 stearoyl-CoA + NBD-labelled sphinganine NBD-labelled sphinganine is (2S,3R)-2-amino-18-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)octadecane-1,3-diol Homo sapiens N-(stearoyl)-sphinganine + CoA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.299 CerS1
-
 Homo sapiens
2.3.1.299 LASS1
-
 Homo sapiens