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Literature summary extracted from

  • Cao, W.; Ma, W.; Zhang, B.; Wang, X.; Chen, K.; Li, Y.; Ouyang, P.
    Improved pinocembrin production in Escherichia coli by engineering fatty acid synthesis (2016), J. Ind. Microbiol. Biotechnol., 43, 557-566 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.179 expressed in Escherichia coli BL21(DE3) cells Escherichia coli
2.3.1.180 expressed in Escherichia coli BL21(DE3) cells Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.179 cerulenin
-
 Escherichia coli
2.3.1.180 cerulenin
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.179 a (Z)-hexadec-9-enoyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein] Escherichia coli
-
 a (Z)-3-oxooctadeca-11-enoyl-[acyl-carrier protein] + CO2 + an [acyl-carrier protein]
-
 ?
2.3.1.180 acetyl-CoA + a malonyl-[acyl-carrier protein] Escherichia coli
-
 an acetoacetyl-[acyl-carrier protein] + CoA + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.179 Escherichia coli P0AAI5
-
-
2.3.1.180 Escherichia coli P0A6R0
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.179 a (Z)-hexadec-9-enoyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein]
-
 Escherichia coli a (Z)-3-oxooctadeca-11-enoyl-[acyl-carrier protein] + CO2 + an [acyl-carrier protein]
-
 ?
2.3.1.180 acetyl-CoA + a malonyl-[acyl-carrier protein]
-
 Escherichia coli an acetoacetyl-[acyl-carrier protein] + CoA + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.179 ? x * 43000, SDS-PAGE Escherichia coli
2.3.1.180 ? x * 34000, SDS-PAGE Escherichia coli

Synonyms

EC Number Synonyms Comment Organism
2.3.1.179 beta-ketoacyl-ACP synthase II
-
 Escherichia coli
2.3.1.179 FabF
-
 Escherichia coli
2.3.1.180 beta-ketoacyl-ACP synthase III
-
 Escherichia coli
2.3.1.180 FabH
-
 Escherichia coli

General Information

EC Number General Information Comment Organism
2.3.1.179 metabolism enzyme overexpression increases pinocembrin production in recombinant Escherichia coli Escherichia coli
2.3.1.180 metabolism enzyme overexpression increases pinocembrin production in recombinant Escherichia coli Escherichia coli