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Literature summary extracted from

  • Li, Y.; Yun, J.; Liu, L.; Li, Y.; Wang, X.
    Identification of two genes encoding for the late acyltransferases of lipid A in Klebsiella pneumoniae (2016), Curr. Microbiol., 73, 732-738 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.241 overexpression in Escherichia coli Klebsiella pneumoniae

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.241 Klebsiella pneumoniae B5XXK1
-
-
2.3.1.241 Klebsiella pneumoniae B5Y0A8
-
-
2.3.1.241 Klebsiella pneumoniae 342 B5XXK1
-
-
2.3.1.241 Klebsiella pneumoniae 342 B5Y0A8
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.241 a dodecanoyl-[acyl-carrier protein] + Kdo2-lipid IVA LpxL1 transfers a C12:0 acyl chain to the 2-O at the (3R)-hydroxytetradecanoyl chain on the 2'-glucosaminyl moity of Kdo2-lipid IVA Klebsiella pneumoniae dodecanoyl-Kdo2-lipid IVA + an [acyl-carrier protein]
-
 ?
2.3.1.241 a dodecanoyl-[acyl-carrier protein] + Kdo2-lipid IVA LpxL1 transfers a C12:0 acyl chain to the 2-O at the (3R)-hydroxytetradecanoyl chain on the 2'-glucosaminyl moity of Kdo2-lipid IVA Klebsiella pneumoniae 342 dodecanoyl-Kdo2-lipid IVA + an [acyl-carrier protein]
-
 ?
2.3.1.241 a tetradecanoyl-[acyl-carrier protein] + Kdo2-lipid IVA
-
 Klebsiella pneumoniae tetradecanoyl-Kdo2-lipid IVA + an [acyl-carrier protein]
-
 ?
2.3.1.241 a tetradecanoyl-[acyl-carrier protein] + Kdo2-lipid IVA
-
 Klebsiella pneumoniae 342 tetradecanoyl-Kdo2-lipid IVA + an [acyl-carrier protein]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.241 lpxL_1
-
 Klebsiella pneumoniae
2.3.1.241 lpxL_2
-
 Klebsiella pneumoniae

General Information

EC Number General Information Comment Organism
2.3.1.241 physiological function the enzyme might play an important role in the biosynthesis of lipid A and the innate immune system recognition in Klebsiella pneumoniae Klebsiella pneumoniae