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Literature summary extracted from

  • Gao, T.; Gu, S.; Liu, F.; Li, L.; Wang, Z.; Yang, J.; Li, G.
    Investigation of MTH1 activity via mismatch-based DNA chain elongation (2016), Anal. Chim. Acta, 905, 66-71 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.55 N4-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine i.e. TH588 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.55 8-oxo-dGTP + H2O Homo sapiens
-
 8-oxo-dGMP + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.55 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.55 MCF-10A cell
-
 Homo sapiens
-
3.6.1.55 MCF-7 cell
-
 Homo sapiens
-
3.6.1.55 MDA-MB-231 cell
-
 Homo sapiens
-
3.6.1.55 T-47D cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.55 8-oxo-dGTP + H2O
-
 Homo sapiens 8-oxo-dGMP + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.6.1.55 8-oxo-dGTPase
-
 Homo sapiens
3.6.1.55 MTH1
-
 Homo sapiens
3.6.1.55 MutT homolog 1
-
 Homo sapiens