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Literature summary extracted from

  • Sato, T.; Aokit, J.; Nagai, Y.; Dohmae, N.; Takio, K.; Doi, T.; Arai, H.; Inoue, K.
    Serine phospholipid-specific phospholipase a that is secreted from activated platelets. A new member of the lipase family (1997), J. Biol. Chem., 272, 2192-2198 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.111 expression in Sf9 cell Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.111 diisopropyl fluorophosphate
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.111 extracellular
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.111 Rattus norvegicus P97535
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.111 from extracellular medium of thrombin-activated blood platelets Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.111 blood platelet
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.111 1800
-
 substrate 1-oleoyl-sn-glycero-3-phophoserine, pH 7.5, 37°C Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.111 1-oleoyl-sn-glycero-3-phophoserine + H2O
-
 Rattus norvegicus glycerophosphoserine + oleate
-
 ?
3.1.1.111 additional information enzyme hydrolyzes a fatty acyl residue at the sn-1 position of lysophosphatidylserine and phosphatidylserine, but does not appreciably hydrolyze phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, phosphatidic acid, and triglyceride Rattus norvegicus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.111 ? x * 55000, SDS-PAGE Rattus norvegicus