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Literature summary extracted from

  • Bhatt, A.; Kremer, L.; Dai, A.Z.; Sacchettini, J.C.; Jacobs, W.R.
    Conditional depletion of KasA, a key enzyme of mycolic acid biosynthesis, leads to mycobacterial cell lysis (2005), J. Bacteriol., 187, 7596-7606 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.293 Mycolicibacterium smegmatis
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2.3.1.293 Mycolicibacterium smegmatis mc2155
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Synonyms

EC Number Synonyms Comment Organism
2.3.1.293 beta-ketoacyl-acyl carrier protein synthase
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 Mycolicibacterium smegmatis
2.3.1.293 KasA
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 Mycolicibacterium smegmatis

General Information

EC Number General Information Comment Organism
2.3.1.293 malfunction depletion of the enzyme leads to mycobacterial cell lysis and inhibition of alpha and epoxy mycolate biosynthesis and to accumulation of alpha'-mycolates Mycolicibacterium smegmatis
2.3.1.293 metabolism key enzyme of mycolic acid biosynthesis Mycolicibacterium smegmatis