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Literature summary extracted from
- Development and in vitro characterization of a papain loaded mucolytic self-emulsifying drug delivery system (SEDDS) (2017), Int. J. Pharm., 530, 346-353 .
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.4.22.2 | medicine | a potential new self-emulsifying drug delivery system with mucolytic features for oral administration is developed. Using hydrophobic ion pairing, papain can be successfully included in the system. Within all formulations papain exhibits a mucolytic effect and accelerates a higher permeation in porcine intestinal mucus. Additionally a prolonged mucosal residence confirms that upon incorporation of enzyme, self-emulsifying drug delivery systems are awarded with the ability to overcome the intestinal barrier more easily. This system can be presented as a promising carrier capable to transport a therapeutic ingredient across the mucus barrier and finally improve its bioavailability | Carica papaya |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.2 | Carica papaya | P00784 | - |
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