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Literature summary extracted from

  • Xin, D.; Ge, X.; Sun, Z.; Viikari, L.; Zhang, J.
    Competitive inhibition of cellobiohydrolase I by manno-oligosaccharides (2015), Enzyme Microb. Technol., 68, 62-68 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.91 Mannan
-
Thermoascus aurantiacus
3.2.1.91 mannobiose strong inhibition, effect on enzyme kinetics, overview Thermoascus aurantiacus
3.2.1.91 Mannotetraose effect on enzyme kinetics, overview Thermoascus aurantiacus
3.2.1.91 Mannotriose effect on enzyme kinetics, overview Thermoascus aurantiacus
3.2.1.91 additional information manno-oligosaccharides, MOS, are competitive inhibitors ofthe CBHI. The negative effects of mannan and manno-oligosaccharides (MOS) on the hydrolytic action of cellulases indicates that the inhibitory effect is at least partly attributed to the inhibition of Ta Cel7A (CBHI), but not on beta-glucosidase Thermoascus aurantiacus
3.2.1.91 xylan both soluble and insoluble xylans inhibit the activities of CBHI Thermoascus aurantiacus
3.2.1.91 xylo-oligosaccharides XOS, competitive inhibitors of CBHI from Thermoascus aurantiacus Thermoascus aurantiacus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.91 0.67
-
4-nitrophenyl beta-D-cellobioside pH 5.0, 50°C Thermoascus aurantiacus

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.91 Thermoascus aurantiacus A7WNU2
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.91 4-nitrophenyl beta-D-cellobioside + H2O
-
Thermoascus aurantiacus 4-nitrophenol + D-cellobiose
-
?
3.2.1.91 avicel + H2O microcrystalline cellulose, Avicel PH-101, at 2% Thermoascus aurantiacus D-glucose + ?
-
?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.91 CBHI
-
Thermoascus aurantiacus
3.2.1.91 Cel7A
-
Thermoascus aurantiacus
3.2.1.91 cellobiohydrolase I
-
Thermoascus aurantiacus
3.2.1.91 glucanase
-
Thermoascus aurantiacus
3.2.1.91 Ta Cel7A
-
Thermoascus aurantiacus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.2.1.91 50
-
-
Thermoascus aurantiacus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.91 5
-
-
Thermoascus aurantiacus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.2.1.91 additional information
-
additional information inhibition kinetics Thermoascus aurantiacus