BRENDA - Enzyme Database

Classification of glycosidases that hydrolyze the specific positions and types of sugar moieties in ginsenosides

Shin, K.; Oh, D.; Crit. Rev. Biotechnol. 36, 1036-1049 (2016) View publication on PubMed

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
3.2.1.B23
ginsenoside C-K + H2O
Rhizobium sp.
-
protopanaxadiol + D-glucose
-
-
?
3.2.1.B23
ginsenoside C-O + H2O
Bifidobacterium choerinum
-
ginsenoside F2 + L-arabinopyranose
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
Thermus thermophilus
-
ginsenoside F2 + D-glucose
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
Bifidobacterium longum
-
ginsenoside F2 + D-glucose
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
Flavobacterium johnsoniae
-
ginsenoside F2 + D-glucose
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
Bifidobacterium longum H-1
-
ginsenoside F2 + D-glucose
-
-
?
3.2.1.B23
ginsenoside G75 + H2O
Thermus thermophilus
-
ginsenoside C-K + D-glucose
-
-
?
3.2.1.B23
ginsenoside Mc + H2O
Caldicellulosiruptor saccharolyticus
-
ginsenoside C-K + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Mc + H2O
Rhodanobacter ginsenosidimutans
-
ginsenoside C-K + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Mc1 + H2O
Rhodanobacter ginsenosidimutans
-
ginsenoside F2 + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Thermus thermophilus
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Trichoderma viride
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Aspergillus sp.
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Bifidobacterium longum
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Lissachatina fulica
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Passalora fulva
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Pseudothermotoga thermarum
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Flavobacterium johnsoniae
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Aspergillus niger
-
ginsenoside Rg3 + 2 D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Pseudonocardia sp.
-
ginsenoside Rg3 + 2 D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Microbacterium esteraromaticum
-
ginsenoside Rg3 + 2 D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Bifidobacterium longum H-1
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Pseudothermotoga thermarum DSM 5069T
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
Trichoderma viride
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
Bifidobacterium longum
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
Bifidobacterium choerinum
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
Microbacterium esteraromaticum
-
ginsenoside Rg3 + D-glucose + L-arabinopyranose
-
-
?
3.2.1.B23
ginsenoside Rb3 + H2O
Pseudonocardia sp.
-
ginsenoside Rg3 + D-glucose + D-xylose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Bifidobacterium breve
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Trichoderma viride
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Caldicellulosiruptor saccharolyticus
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Bifidobacterium longum
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Panax ginseng
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Leuconostoc sp.
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Rhodanobacter ginsenosidimutans
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Bifidobacterium longum H-1
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rd + H2O
Pseudonocardia sp.
-
ginsenoside Rg3 + D-glucose
-
-
?
3.2.1.B23
ginsenoside Re + H2O
Mucilaginibacter sp. QM49
-
ginsenoside Rg2 + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rg1 + H2O
Mucilaginibacter sp. QM49
-
ginsenoside Rh1 + D-glucose
-
-
?
3.2.1.B23
additional information
Thermus thermophilus
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Trichoderma viride
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Aspergillus sp.
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Bifidobacterium longum
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Lissachatina fulica
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Passalora fulva
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Pseudothermotoga thermarum
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Flavobacterium johnsoniae
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Bifidobacterium breve
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
?
-
-
?
3.2.1.B23
additional information
Trichoderma viride
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
?
-
-
?
3.2.1.B23
additional information
Caldicellulosiruptor saccharolyticus
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
?
-
-
?
3.2.1.B23
additional information
Bifidobacterium longum
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
?
-
-
?
3.2.1.B23
additional information
Bifidobacterium choerinum
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
?
-
-
?
3.2.1.B23
additional information
Bifidobacterium longum H-1
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Bifidobacterium longum H-1
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
?
-
-
?
3.2.1.B23
additional information
Pseudothermotoga thermarum DSM 5069T
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
Sphingomonas sp.
-
ginsenoside G17 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
Sphingopyxis alaskensis
-
ginsenoside G17 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
Esteya vermicola
via ginsenoside G17
ginsenoside G75 + 2 D-glucose
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
Esteya vermicola CNU120806
via ginsenoside G17
ginsenoside G75 + 2 D-glucose
-
-
?
3.2.1.191
ginsenoside Rb2 + H2O
Sphingomonas sp.
-
ginsenoside C-O + D-glucose
-
-
?
3.2.1.191
ginsenoside Rb2 + H2O
Sphingopyxis alaskensis
-
ginsenoside C-O + D-glucose
-
-
?
3.2.1.191
ginsenoside Rc + H2O
Sphingomonas sp.
-
ginsenoside C-Mc1 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rc + H2O
Sphingopyxis alaskensis
-
ginsenoside C-Mc1 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rd + H2O
Esteya vermicola
via ginsenosside F2
ginsenoside C-K + 2 D-glucose
-
-
?
3.2.1.191
ginsenoside Rd + H2O
Sphingomonas sp.
-
ginsenoside F2 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rd + H2O
Sphingopyxis alaskensis
-
ginsenoside F2 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rd + H2O
Esteya vermicola CNU120806
via ginsenosside F2
ginsenoside C-K + 2 D-glucose
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
Fusarium sp.
-
ginsenoside Rh2 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
Fusarium proliferatum
-
ginsenoside Rh2 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
Panax ginseng
-
ginsenoside Rh2 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
Sphingopyxis alaskensis
-
ginsenoside Rh2 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
Fusarium proliferatum ECU2042
-
ginsenoside Rh2 + D-glucose
-
-
?
3.2.1.191
additional information
Aspergillus niger
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Fusarium sp.
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Sphingomonas sp.
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Fusarium proliferatum
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Panax ginseng
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Terrabacter ginsenosidimutans
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Sphingopyxis alaskensis
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Esteya vermicola
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Esteya vermicola CNU120806
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Fusarium proliferatum ECU2042
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.193
ginsenoside F2 + H2O
Sphingomonas leidyi
-
ginsenoside C-K + D-glucose
-
-
?
3.2.1.193
ginsenoside F2 + H2O
Aspergillus oryzae
-
ginsenoside C-K + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Saccharolobus solfataricus
via ginsenoside F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Aspergillus sp.
via ginsenoside F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Leuconostoc citreum
via ginsenoside F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Sulfolobus acidocaldarius
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Leuconostoc mesenteroides
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Lactiplantibacillus pentosus
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Microbacterium esteraromaticum
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Fusobacterium sp.
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Companilactobacillus paralimentarius
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Sphingomonas leidyi
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Aspergillus niger
via ginsenosides Rd and F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Aspergillus oryzae
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Pseudarthrobacter chlorophenolicus
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Intrasporangium sp.
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Globisporangium irregulare
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Nocardioides panaciterrulae
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Sphingomonas leidyi
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Byssochlamys spectabilis
-
ginsenoside Rg3 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Citrus limon
-
ginsenoside Rg3 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Aspergillus sp.
via ginsenoside F2
ginsenoside Rh2 + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Byssochlamys spectabilis 229-7
-
ginsenoside Rg3 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Lactiplantibacillus pentosus 6105
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Intrasporangium sp. GS603
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Leuconostoc mesenteroides DC102
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Leuconostoc citreum LH1
via ginsenoside F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Aspergillus niger g.848
via ginsenosides Rd and F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Aspergillus oryzae
-
ginsenoside F2 + D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Pseudarthrobacter chlorophenolicus
-
ginsenoside F2 + D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Globisporangium irregulare
-
ginsenoside F2 + D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Sulfolobus acidocaldarius
-
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Microbacterium esteraromaticum
-
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Saccharolobus solfataricus
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Aspergillus sp.
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Aspergillus niger
via ginsenosides Rd and F2
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Citrus limon
-
ginsenoside Rg3 + D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Aspergillus sp.
via ginsenoside F2
ginsenoside Rh2 + 2 D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Aspergillus niger g.848
via ginsenosides Rd and F2
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb3 + H2O
Aspergillus niger
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + xylose
-
-
?
3.2.1.193
ginsenoside Rb3 + H2O
Aspergillus niger g.848
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + xylose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Aspergillus oryzae
-
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Pseudarthrobacter chlorophenolicus
-
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Globisporangium irregulare
-
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Nocardioides panaciterrulae
-
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Aspergillus niger
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Saccharolobus solfataricus
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Aspergillus sp.
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Citrus limon
-
ginsenoside Rg3 + D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Aspergillus sp.
via ginsenoside F2
ginsenoside Rh2 + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Aspergillus niger g.848
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rd + H2O
Byssochlamys spectabilis
-
ginsenoside Rg3 + D-glucose
-
-
?
3.2.1.193
ginsenoside Rd + H2O
Byssochlamys spectabilis 229-7
-
ginsenoside Rg3 + D-glucose
-
-
?
3.2.1.193
additional information
Aspergillus niger
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Byssochlamys spectabilis
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Sulfolobus acidocaldarius
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Leuconostoc mesenteroides
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Lactiplantibacillus pentosus
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Saccharolobus solfataricus
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Aspergillus oryzae
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Aspergillus sp.
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Microbacterium esteraromaticum
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Citrus limon
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Leuconostoc citreum
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Fusobacterium sp.
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Pseudarthrobacter chlorophenolicus
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Intrasporangium sp.
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Globisporangium irregulare
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Nocardioides panaciterrulae
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Companilactobacillus paralimentarius
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Sphingomonas leidyi
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Byssochlamys spectabilis 229-7
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Lactiplantibacillus pentosus 6105
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Intrasporangium sp. GS603
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Leuconostoc mesenteroides DC102
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Leuconostoc citreum LH1
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Aspergillus niger g.848
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.194
ginsenoside R1 + H2O
Aspergillus sp.
-
ginsenoside F1 + D-glucose + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Re + H2O
Pyrococcus furiosus
-
ginsenoside Rg1 + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Re + H2O
Aspergillus sp.
-
ginsenoside F1 + D-glucose + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Re + H2O
Penicillium decumbens
-
ginsenoside F1 + D-glucose + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Rf + H2O
Aspergillus niger
-
ginsenoside Rh1 + D-glucose
-
-
?
3.2.1.194
ginsenoside Rf + H2O
Pyrococcus furiosus
-
ginsenoside Rh1 + D-glucose
-
-
?
3.2.1.194
ginsenoside Rf + H2O
Aspergillus sp.
-
protopanaxatriol + 2 D-glucose
-
-
?
3.2.1.194
ginsenoside Rf + H2O
Penicillium decumbens
-
protopanaxatriol + 2 D-glucose
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
Penicillium decumbens
-
ginsenoside F1 + D-glucose
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
Fusarium subglutinans
-
ginsenoside F1 + D-glucose
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
Penicillium sclerotiorum
-
ginsenoside F1 + D-glucose
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
Sanguibacter keddieii
-
ginsenoside F1 + D-glucose
-
-
?
3.2.1.194
ginsenoside Rg2 + 2 H2O
Penicillium decumbens
-
protopanaxatriol + D-glucose + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
Pyrococcus furiosus
-
ginsenoside Rh1 + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
Thermoanaerobacterium thermosaccharolyticum
-
ginsenoside Rh1 + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
Absidia sp. (in: Fungi)
-
ginsenoside Rh1 + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
Aspergillus sp.
-
protopanaxatriol + D-glucose + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Rh1 + H2O
Penicillium decumbens
-
protopanaxatriol + D-glucose
-
-
?
3.2.1.194
additional information
Pyrococcus furiosus
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1
?
-
-
?
3.2.1.194
additional information
Aspergillus niger
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1. This conversion has been conducted by beta-glycosidase from Aspergillus niger
?
-
-
?
3.2.1.194
additional information
Absidia sp. (in: Fungi)
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2
?
-
-
?
3.2.1.194
additional information
Pyrococcus furiosus
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2. This conversion was performed using b-glycosidase from Pyrococcus furiosus
?
-
-
?
3.2.1.194
additional information
Pyrococcus furiosus
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
?
-
-
?
3.2.1.194
additional information
Thermoanaerobacterium thermosaccharolyticum
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
?
-
-
?
3.2.1.194
additional information
Penicillium decumbens
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
?
-
-
?
3.2.1.194
additional information
Fusarium subglutinans
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
?
-
-
?
3.2.1.194
additional information
Penicillium sclerotiorum
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
?
-
-
?
3.2.1.194
additional information
Sanguibacter keddieii
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
?
-
-
?
3.2.1.194
additional information
Aspergillus sp.
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-ii enzymes convert ginsenosides Rg1 and Rh1, containing only the inner glucose without the outer sugar at C-6, are converted to ginsenosides F1 and aglycone protopanaxatriol (APPT), respectively, by hydrolyzing the inner glucose linked to C-6 but not the glucose linked to C-20 in the PPT-type ginsenosides with the hydrolysis pattern of F. Ginsenosidase type IV-ii enzymes also hydrolyze the outer glucose of ginsenoside Rf, which has the outer and inner glucose at C-6 with the hydrolysis pattern of E-1; the outer rhamnose of ginsenosides Re and Rg2, which have the outer rhamnose and inner glucose at C-6 with the hydrolysis attern of E-2, and the outer xylose of notoginsenosides R1 and R2, which contain the outer xylose and inner glucose at C-6 with the hydrolysis pattern of E-3
?
-
-
?
3.2.1.194
notoginsenoside R1 + H2O
Pyrococcus furiosus
-
ginsenoside Rg1 + D-xylose
-
-
?
3.2.1.194
notoginsenoside R1 + H2O
Thermoanaerobacterium thermosaccharolyticum
-
ginsenoside Rg1 + D-xylose
-
-
?
3.2.1.195
ginsenoside Re + H2O
Penicillium sp.
-
ginsenoside Rh1 + D-glucose + L-rhamnose
-
-
?
3.2.1.195
ginsenoside Re + H2O
Actinosynnema mirum
-
ginsenoside Rh1 + D-glucose + L-rhamnose
-
-
?
3.2.1.195
ginsenoside Rg1 + H2O
Penicillium sp.
via ginsenoside Rh1
protopanaxatriol + 2 D-glucose
-
-
?
3.2.1.195
ginsenoside Rg1 + H2O
Actinosynnema mirum
via ginsenoside Rh1
protopanaxatriol + 2 D-glucose
-
-
?
3.2.1.195
additional information
Penicillium sp.
ginsenosidase type V enzymes hydrolyze the sugars linked to C-20 and C-6 in the PPD-type ginsenosides with the hydrolysis patterns of B, E and F. Crude enzyme from Penicillium sp. and beta-glucosidase from Actinosynnema mirum convert ginsenosides Re and Rg1 to Rh1 and APPT, respectively
?
-
-
?
3.2.1.195
additional information
Actinosynnema mirum
ginsenosidase type V enzymes hydrolyze the sugars linked to C-20 and C-6 in the PPD-type ginsenosides with the hydrolysis patterns of B, E and F. Crude enzyme from Penicillium sp. and beta-glucosidase from Actinosynnema mirum convert ginsenosides Re and Rg1 to Rh1 and APPT, respectively
?
-
-
?
Organism
EC Number
Organism
UniProt
Commentary
Textmining
3.2.1.B23
Aspergillus niger
-
-
-
3.2.1.B23
Aspergillus sp.
-
-
-
3.2.1.B23
Bifidobacterium breve
-
-
-
3.2.1.B23
Bifidobacterium choerinum
-
-
-
3.2.1.B23
Bifidobacterium longum
-
-
-
3.2.1.B23
Bifidobacterium longum H-1
-
-
-
3.2.1.B23
Caldicellulosiruptor saccharolyticus
-
-
-
3.2.1.B23
Flavobacterium johnsoniae
-
-
-
3.2.1.B23
Leuconostoc sp.
-
-
-
3.2.1.B23
Lissachatina fulica
-
-
-
3.2.1.B23
Microbacterium esteraromaticum
-
-
-
3.2.1.B23
Mucilaginibacter sp. QM49
-
-
-
3.2.1.B23
Panax ginseng
-
-
-
3.2.1.B23
Passalora fulva
-
-
-
3.2.1.B23
Pseudonocardia sp.
-
-
-
3.2.1.B23
Pseudothermotoga thermarum
-
-
-
3.2.1.B23
Pseudothermotoga thermarum DSM 5069T
-
-
-
3.2.1.B23
Rhizobium sp.
-
-
-
3.2.1.B23
Rhodanobacter ginsenosidimutans
-
-
-
3.2.1.B23
Thermus thermophilus
-
-
-
3.2.1.B23
Trichoderma viride
-
-
-
3.2.1.191
Aspergillus niger
-
-
-
3.2.1.191
Esteya vermicola
-
-
-
3.2.1.191
Esteya vermicola CNU120806
-
-
-
3.2.1.191
Fusarium proliferatum
-
-
-
3.2.1.191
Fusarium proliferatum ECU2042
-
-
-
3.2.1.191
Fusarium sp.
-
-
-
3.2.1.191
Panax ginseng
-
-
-
3.2.1.191
Sphingomonas sp.
-
-
-
3.2.1.191
Sphingopyxis alaskensis
-
-
-
3.2.1.191
Terrabacter ginsenosidimutans
-
-
-
3.2.1.193
Aspergillus niger
-
-
-
3.2.1.193
Aspergillus niger g.848
-
-
-
3.2.1.193
Aspergillus oryzae
-
-
-
3.2.1.193
Aspergillus sp.
-
-
-
3.2.1.193
Byssochlamys spectabilis
-
i.e. Paecilomyces bainier
-
3.2.1.193
Byssochlamys spectabilis 229-7
-
i.e. Paecilomyces bainier
-
3.2.1.193
Citrus limon
-
-
-
3.2.1.193
Companilactobacillus paralimentarius
-
-
-
3.2.1.193
Fusobacterium sp.
-
-
-
3.2.1.193
Globisporangium irregulare
-
-
-
3.2.1.193
Intrasporangium sp.
-
-
-
3.2.1.193
Intrasporangium sp. GS603
-
-
-
3.2.1.193
Lactiplantibacillus pentosus
-
-
-
3.2.1.193
Lactiplantibacillus pentosus 6105
-
-
-
3.2.1.193
Leuconostoc citreum
-
isolated from kimchi
-
3.2.1.193
Leuconostoc citreum LH1
-
isolated from kimchi
-
3.2.1.193
Leuconostoc mesenteroides
-
-
-
3.2.1.193
Leuconostoc mesenteroides DC102
-
-
-
3.2.1.193
Microbacterium esteraromaticum
-
-
-
3.2.1.193
Nocardioides panaciterrulae
-
sp. nov., isolated from soil of a ginseng field
-
3.2.1.193
Pseudarthrobacter chlorophenolicus
-
-
-
3.2.1.193
Saccharolobus solfataricus
-
-
-
3.2.1.193
Sphingomonas leidyi
-
-
-
3.2.1.193
Sulfolobus acidocaldarius
-
-
-
3.2.1.194
Absidia sp. (in: Fungi)
-
-
-
3.2.1.194
Aspergillus niger
-
-
-
3.2.1.194
Aspergillus sp.
-
-
-
3.2.1.194
Fusarium subglutinans
-
-
-
3.2.1.194
Penicillium decumbens
-
-
-
3.2.1.194
Penicillium sclerotiorum
-
-
-
3.2.1.194
Pyrococcus furiosus
-
-
-
3.2.1.194
Sanguibacter keddieii
-
-
-
3.2.1.194
Thermoanaerobacterium thermosaccharolyticum
-
-
-
3.2.1.195
Actinosynnema mirum
-
-
-
3.2.1.195
Penicillium sp.
-
-
-
Purification (Commentary)
EC Number
Purification (Commentary)
Organism
3.2.1.191
native enzyme
Esteya vermicola
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
3.2.1.B23
3
-
pH 5.0, 50°C
Panax ginseng
3.2.1.B23
4
-
pH 8.0, 30°C
Mucilaginibacter sp. QM49
3.2.1.B23
5
-
pH 6.5, 90°C
Thermus thermophilus
3.2.1.B23
8
-
pH 6.8, 37°C
Bifidobacterium longum
3.2.1.B23
9
-
pH 5.5, 37°C
Bifidobacterium breve
3.2.1.B23
15
-
pH 7.5, 37°C
Rhodanobacter ginsenosidimutans
3.2.1.B23
18
-
pH 6.0, 45°C
Passalora fulva
3.2.1.B23
22
-
pH 5.5, 35°C
Bifidobacterium longum
3.2.1.B23
24
-
pH 5.5, 45°C
Passalora fulva
3.2.1.B23
26
-
pH 6.0, 37°C
Leuconostoc sp.
3.2.1.B23
28
-
pH 5.5, 80°C
Caldicellulosiruptor saccharolyticus
3.2.1.B23
40
-
pH 7.0, 37°C
Pseudonocardia sp.
3.2.1.B23
61
-
pH 7.0, 40°C
Microbacterium esteraromaticum
3.2.1.B23
67
-
pH 4.7, 37°C
Bifidobacterium longum
3.2.1.B23
140
-
pH 4.8, 90°C
Pseudothermotoga thermarum
3.2.1.B23
250
-
pH 5.6, 70°C
Lissachatina fulica
3.2.1.191
2
-
pH 5.0, 60°C, substrate ginsenoside Rg3
Panax ginseng
3.2.1.191
76
-
purified enzyme, pH 7.0, 37°C
Terrabacter ginsenosidimutans
3.2.1.191
290
-
purified native enzyme, pH 5.0, 50°C
Esteya vermicola
3.2.1.191
309
-
pH 5.5, 40°C
Sphingopyxis alaskensis
3.2.1.193
29
-
pH 7.0, 40°C
Microbacterium esteraromaticum
3.2.1.193
137
-
pH 3.5, 60°C
Byssochlamys spectabilis
3.2.1.193
2020
-
pH 5.5, 90°C
Saccharolobus solfataricus
3.2.1.194
1
-
pH 5.0, 40°C
Absidia sp. (in: Fungi)
3.2.1.194
2
-
pH 5.5, 95°C
Pyrococcus furiosus
3.2.1.194
2
-
substrate ginsenoside Rf, pH 6.0, 40°C
Aspergillus sp.
3.2.1.194
4
-
substrate ginsenoside Rf, pH 7.5, 37°C
Aspergillus niger
3.2.1.194
4.5
-
pH 6.5, 60°C
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
136
-
pH 6.0, 50°C
Fusarium subglutinans
3.2.1.194
136
-
pH 6.0, 50°C
Penicillium sclerotiorum
3.2.1.194
912
-
pH 6.0, 40°C
Pyrococcus furiosus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
3.2.1.B23
ginsenoside C-K + H2O
-
753334
Rhizobium sp.
protopanaxadiol + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside C-O + H2O
-
753334
Bifidobacterium choerinum
ginsenoside F2 + L-arabinopyranose
-
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
-
753334
Thermus thermophilus
ginsenoside F2 + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
-
753334
Bifidobacterium longum
ginsenoside F2 + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
-
753334
Flavobacterium johnsoniae
ginsenoside F2 + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
-
753334
Bifidobacterium longum H-1
ginsenoside F2 + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside G75 + H2O
-
753334
Thermus thermophilus
ginsenoside C-K + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Mc + H2O
-
753334
Caldicellulosiruptor saccharolyticus
ginsenoside C-K + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Mc + H2O
-
753334
Rhodanobacter ginsenosidimutans
ginsenoside C-K + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Mc1 + H2O
-
753334
Rhodanobacter ginsenosidimutans
ginsenoside F2 + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Thermus thermophilus
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Trichoderma viride
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Aspergillus sp.
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Bifidobacterium longum
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Lissachatina fulica
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Passalora fulva
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Pseudothermotoga thermarum
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Flavobacterium johnsoniae
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Bifidobacterium longum H-1
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Pseudothermotoga thermarum DSM 5069T
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Aspergillus niger
ginsenoside Rg3 + 2 D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Pseudonocardia sp.
ginsenoside Rg3 + 2 D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Microbacterium esteraromaticum
ginsenoside Rg3 + 2 D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
-
753334
Trichoderma viride
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
-
753334
Bifidobacterium longum
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
-
753334
Bifidobacterium choerinum
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
-
753334
Microbacterium esteraromaticum
ginsenoside Rg3 + D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.B23
ginsenoside Rb3 + H2O
-
753334
Pseudonocardia sp.
ginsenoside Rg3 + D-glucose + D-xylose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Bifidobacterium breve
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Trichoderma viride
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Caldicellulosiruptor saccharolyticus
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Bifidobacterium longum
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Panax ginseng
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Leuconostoc sp.
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Rhodanobacter ginsenosidimutans
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Bifidobacterium longum H-1
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rd + H2O
-
753334
Pseudonocardia sp.
ginsenoside Rg3 + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Re + H2O
-
753334
Mucilaginibacter sp. QM49
ginsenoside Rg2 + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rg1 + H2O
-
753334
Mucilaginibacter sp. QM49
ginsenoside Rh1 + D-glucose
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Thermus thermophilus
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Trichoderma viride
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Aspergillus sp.
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Bifidobacterium longum
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Lissachatina fulica
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Passalora fulva
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Pseudothermotoga thermarum
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Flavobacterium johnsoniae
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
753334
Bifidobacterium breve
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
753334
Trichoderma viride
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
753334
Caldicellulosiruptor saccharolyticus
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
753334
Bifidobacterium longum
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
753334
Bifidobacterium choerinum
?
-
-
-
?
3.2.1.B23
additional information
hydrolysis of the C-20 inner Glc
753334
Aspergillus niger
?
-
-
-
?
3.2.1.B23
additional information
hydrolysis of the C-20 inner Glc
753334
Pseudonocardia sp.
?
-
-
-
?
3.2.1.B23
additional information
hydrolysis of the C-20 inner Glc
753334
Rhizobium sp.
?
-
-
-
?
3.2.1.B23
additional information
hydrolysis of the C-20 inner Glc
753334
Microbacterium esteraromaticum
?
-
-
-
?
3.2.1.B23
additional information
hydrolysis of the C-20 inner Glc
753334
Mucilaginibacter sp. QM49
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Bifidobacterium longum H-1
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
753334
Bifidobacterium longum H-1
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Pseudothermotoga thermarum DSM 5069T
?
-
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
-
753334
Sphingomonas sp.
ginsenoside G17 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
-
753334
Sphingopyxis alaskensis
ginsenoside G17 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
via ginsenoside G17
753334
Terrabacter ginsenosidimutans
ginsenoside G75 + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
via ginsenoside G17
753334
Esteya vermicola
ginsenoside G75 + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
via ginsenoside G17
753334
Esteya vermicola CNU120806
ginsenoside G75 + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb2 + H2O
-
753334
Sphingomonas sp.
ginsenoside C-O + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb2 + H2O
-
753334
Sphingopyxis alaskensis
ginsenoside C-O + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb2 + H2O
via ginsenoside C-O
753334
Terrabacter ginsenosidimutans
ginsenoside C-Y + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb3 + H2O
via ginsenoside C-Mx1
753334
Terrabacter ginsenosidimutans
ginsenoside C-Mx + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rc + H2O
-
753334
Sphingomonas sp.
ginsenoside C-Mc1 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rc + H2O
-
753334
Sphingopyxis alaskensis
ginsenoside C-Mc1 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rc + H2O
via ginsenoside C-Mc1
753334
Terrabacter ginsenosidimutans
ginsenoside C-Mc + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
via ginsenoside F2
753334
Esteya vermicola
ginsenoside C-K + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
via ginsenosside F2
753334
Terrabacter ginsenosidimutans
ginsenoside C-K + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
via ginsenosside F2
753334
Esteya vermicola
ginsenoside C-K + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
via ginsenoside F2
753334
Esteya vermicola CNU120806
ginsenoside C-K + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
via ginsenosside F2
753334
Esteya vermicola CNU120806
ginsenoside C-K + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
-
753334
Sphingomonas sp.
ginsenoside F2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
-
753334
Sphingopyxis alaskensis
ginsenoside F2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
-
753334
Fusarium sp.
ginsenoside Rh2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
-
753334
Fusarium proliferatum
ginsenoside Rh2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
-
753334
Panax ginseng
ginsenoside Rh2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
-
753334
Sphingopyxis alaskensis
ginsenoside Rh2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
-
753334
Fusarium proliferatum ECU2042
ginsenoside Rh2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
via ginsenoside Rh2
753334
Terrabacter ginsenosidimutans
protopanaxadiol aglycone + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
via ginsenoside Rh2, hydrolysis of the inner glucose at C-3
753334
Aspergillus niger
protopanaxadiol aglycone + 2 D-glucose
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Aspergillus niger
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Fusarium sp.
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Sphingomonas sp.
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Fusarium proliferatum
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Panax ginseng
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Terrabacter ginsenosidimutans
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Sphingopyxis alaskensis
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Esteya vermicola
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Aspergillus niger
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Fusarium sp.
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Sphingomonas sp.
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Fusarium proliferatum
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Panax ginseng
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Terrabacter ginsenosidimutans
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Esteya vermicola
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides. beta-Glucosidase from Sphingopyxis alaskensis hydrolyzes only the outer glucose at C-3 in ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to product G17, C-O, C-Mc1, F2 and Rh2, respectively, without further hydrolysis
753334
Sphingopyxis alaskensis
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Esteya vermicola CNU120806
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Esteya vermicola CNU120806
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Fusarium proliferatum ECU2042
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Fusarium proliferatum ECU2042
?
-
-
-
?
3.2.1.193
ginsenoside F2 + H2O
-
753334
Sphingomonas leidyi
ginsenoside C-K + D-glucose
-
-
-
?
3.2.1.193
ginsenoside F2 + H2O
-
753334
Aspergillus oryzae
ginsenoside C-K + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenoside F2
753334
Saccharolobus solfataricus
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenoside F2
753334
Aspergillus sp.
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenoside F2
753334
Leuconostoc citreum
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Sulfolobus acidocaldarius
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Leuconostoc mesenteroides
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Lactiplantibacillus pentosus
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Microbacterium esteraromaticum
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Fusobacterium sp.
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Companilactobacillus paralimentarius
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Sphingomonas leidyi
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides Rd and F2
753334
Aspergillus niger
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Lactiplantibacillus pentosus 6105
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Leuconostoc mesenteroides DC102
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenoside F2
753334
Leuconostoc citreum LH1
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides Rd and F2
753334
Aspergillus niger g.848
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Aspergillus oryzae
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Pseudarthrobacter chlorophenolicus
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Intrasporangium sp.
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Globisporangium irregulare
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Nocardioides panaciterrulae
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Sphingomonas leidyi
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Intrasporangium sp. GS603
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Byssochlamys spectabilis
ginsenoside Rg3 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Citrus limon
ginsenoside Rg3 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Byssochlamys spectabilis 229-7
ginsenoside Rg3 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenoside F2
753334
Aspergillus sp.
ginsenoside Rh2 + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
-
753334
Aspergillus oryzae
ginsenoside F2 + D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
-
753334
Pseudarthrobacter chlorophenolicus
ginsenoside F2 + D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
-
753334
Globisporangium irregulare
ginsenoside F2 + D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
-
753334
Sulfolobus acidocaldarius
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
-
753334
Microbacterium esteraromaticum
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
via ginsenoside F2
753334
Saccharolobus solfataricus
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
via ginsenoside F2
753334
Aspergillus sp.
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
via ginsenosides Rd and F2
753334
Aspergillus niger
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
via ginsenosides Rd and F2
753334
Aspergillus niger g.848
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
-
753334
Citrus limon
ginsenoside Rg3 + D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
via ginsenoside F2
753334
Aspergillus sp.
ginsenoside Rh2 + 2 D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb3 + H2O
via ginsenoside F2
753334
Aspergillus niger
ginsenoside C-K + 2 D-glucose + xylose
-
-
-
?
3.2.1.193
ginsenoside Rb3 + H2O
via ginsenoside F2
753334
Aspergillus niger g.848
ginsenoside C-K + 2 D-glucose + xylose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
-
753334
Aspergillus oryzae
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
-
753334
Pseudarthrobacter chlorophenolicus
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
-
753334
Globisporangium irregulare
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
-
753334
Nocardioides panaciterrulae
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
via ginsenoside F2
753334
Aspergillus niger
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
via ginsenoside F2
753334
Saccharolobus solfataricus
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
via ginsenoside F2
753334
Aspergillus sp.
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
via ginsenoside F2
753334
Aspergillus niger g.848
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
-
753334
Citrus limon
ginsenoside Rg3 + D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
via ginsenoside F2
753334
Aspergillus sp.
ginsenoside Rh2 + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rd + H2O
-
753334
Byssochlamys spectabilis
ginsenoside Rg3 + D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rd + H2O
-
753334
Byssochlamys spectabilis 229-7
ginsenoside Rg3 + D-glucose
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Aspergillus niger
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Byssochlamys spectabilis
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Sulfolobus acidocaldarius
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Leuconostoc mesenteroides
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Lactiplantibacillus pentosus
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Saccharolobus solfataricus
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Aspergillus oryzae
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Aspergillus sp.
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Microbacterium esteraromaticum
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Citrus limon
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Leuconostoc citreum
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Fusobacterium sp.
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Pseudarthrobacter chlorophenolicus
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Intrasporangium sp.
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Globisporangium irregulare
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Nocardioides panaciterrulae
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Companilactobacillus paralimentarius
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Sphingomonas leidyi
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Byssochlamys spectabilis 229-7
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Lactiplantibacillus pentosus 6105
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Intrasporangium sp. GS603
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Leuconostoc mesenteroides DC102
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Leuconostoc citreum LH1
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Aspergillus niger g.848
?
-
-
-
?
3.2.1.194
ginsenoside R1 + H2O
-
753334
Aspergillus sp.
ginsenoside F1 + D-glucose + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Re + H2O
-
753334
Pyrococcus furiosus
ginsenoside Rg1 + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Re + H2O
-
753334
Aspergillus sp.
ginsenoside F1 + D-glucose + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Re + H2O
-
753334
Penicillium decumbens
ginsenoside F1 + D-glucose + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Rf + H2O
-
753334
Aspergillus niger
ginsenoside Rh1 + D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rf + H2O
-
753334
Pyrococcus furiosus
ginsenoside Rh1 + D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rf + H2O
-
753334
Aspergillus sp.
protopanaxatriol + 2 D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rf + H2O
-
753334
Penicillium decumbens
protopanaxatriol + 2 D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
-
753334
Penicillium decumbens
ginsenoside F1 + D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
-
753334
Fusarium subglutinans
ginsenoside F1 + D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
-
753334
Penicillium sclerotiorum
ginsenoside F1 + D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
-
753334
Sanguibacter keddieii
ginsenoside F1 + D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rg2 + 2 H2O
-
753334
Penicillium decumbens
protopanaxatriol + D-glucose + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
-
753334
Pyrococcus furiosus
ginsenoside Rh1 + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
-
753334
Thermoanaerobacterium thermosaccharolyticum
ginsenoside Rh1 + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
-
753334
Absidia sp. (in: Fungi)
ginsenoside Rh1 + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
-
753334
Aspergillus sp.
protopanaxatriol + D-glucose + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Rh1 + H2O
-
753334
Penicillium decumbens
protopanaxatriol + D-glucose
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1
753334
Pyrococcus furiosus
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1. This conversion has been conducted by beta-glycosidase from Aspergillus niger
753334
Aspergillus niger
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2
753334
Absidia sp. (in: Fungi)
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2. This conversion was performed using b-glycosidase from Pyrococcus furiosus
753334
Pyrococcus furiosus
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
753334
Pyrococcus furiosus
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
753334
Thermoanaerobacterium thermosaccharolyticum
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
753334
Penicillium decumbens
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
753334
Fusarium subglutinans
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
753334
Penicillium sclerotiorum
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
753334
Sanguibacter keddieii
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-ii enzymes convert ginsenosides Rg1 and Rh1, containing only the inner glucose without the outer sugar at C-6, are converted to ginsenosides F1 and aglycone protopanaxatriol (APPT), respectively, by hydrolyzing the inner glucose linked to C-6 but not the glucose linked to C-20 in the PPT-type ginsenosides with the hydrolysis pattern of F. Ginsenosidase type IV-ii enzymes also hydrolyze the outer glucose of ginsenoside Rf, which has the outer and inner glucose at C-6 with the hydrolysis pattern of E-1; the outer rhamnose of ginsenosides Re and Rg2, which have the outer rhamnose and inner glucose at C-6 with the hydrolysis attern of E-2, and the outer xylose of notoginsenosides R1 and R2, which contain the outer xylose and inner glucose at C-6 with the hydrolysis pattern of E-3
753334
Aspergillus sp.
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1. This conversion has been conducted by beta-glycosidase from Pyrococcus furiosus
753334
Pyrococcus furiosus
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2. This conversion is performed using beta-glycosidase from Pyrococcus furiosus
753334
Pyrococcus furiosus
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides. beta-Gglycosidase from Pyrococcus furiosus shows broad substrate specificity that hydrolyzes the outer residue glucose and rhamnose and xylose at C-6
753334
Pyrococcus furiosus
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides. beta-Xylosidase from Thermoanaerobacterium thermosaccharolyticum converts notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1 by selectively hydrolyzing only the outer xylose at C-6
753334
Thermoanaerobacterium thermosaccharolyticum
?
-
-
-
?
3.2.1.194
notoginsenoside R1 + H2O
-
753334
Pyrococcus furiosus
ginsenoside Rg1 + D-xylose
-
-
-
?
3.2.1.194
notoginsenoside R1 + H2O
-
753334
Thermoanaerobacterium thermosaccharolyticum
ginsenoside Rg1 + D-xylose
-
-
-
?
3.2.1.195
ginsenoside Re + H2O
-
753334
Penicillium sp.
ginsenoside Rh1 + D-glucose + L-rhamnose
-
-
-
?
3.2.1.195
ginsenoside Re + H2O
-
753334
Actinosynnema mirum
ginsenoside Rh1 + D-glucose + L-rhamnose
-
-
-
?
3.2.1.195
ginsenoside Rg1 + H2O
via ginsenoside Rh1
753334
Penicillium sp.
protopanaxatriol + 2 D-glucose
-
-
-
?
3.2.1.195
ginsenoside Rg1 + H2O
via ginsenoside Rh1
753334
Actinosynnema mirum
protopanaxatriol + 2 D-glucose
-
-
-
?
3.2.1.195
additional information
ginsenosidase type V enzymes hydrolyze the sugars linked to C-20 and C-6 in the PPD-type ginsenosides with the hydrolysis patterns of B, E and F. Crude enzyme from Penicillium sp. and beta-glucosidase from Actinosynnema mirum convert ginsenosides Re and Rg1 to Rh1 and APPT, respectively
753334
Penicillium sp.
?
-
-
-
?
3.2.1.195
additional information
ginsenosidase type V enzymes hydrolyze the sugars linked to C-20 and C-6 in the PPD-type ginsenosides with the hydrolysis patterns of B, E and F. Crude enzyme from Penicillium sp. and beta-glucosidase from Actinosynnema mirum convert ginsenosides Re and Rg1 to Rh1 and APPT, respectively
753334
Actinosynnema mirum
?
-
-
-
?
Subunits
EC Number
Subunits
Commentary
Organism
3.2.1.B23
?
x * 56000
Rhodanobacter ginsenosidimutans
3.2.1.B23
?
x * 57000
Bifidobacterium longum
3.2.1.B23
?
x * 57000
Pseudothermotoga thermarum
3.2.1.B23
?
x * 49000
Thermus thermophilus
3.2.1.B23
?
x * 58000
Caldicellulosiruptor saccharolyticus
3.2.1.B23
?
x * 58000
Leuconostoc sp.
3.2.1.B23
?
x * 80000
Caldicellulosiruptor saccharolyticus
3.2.1.B23
?
x * 80000
Passalora fulva
3.2.1.B23
?
x * 88000
Microbacterium esteraromaticum
3.2.1.B23
?
x * 60000
Aspergillus sp.
3.2.1.B23
?
x * 86000
Panax ginseng
3.2.1.B23
?
x * 120000
Lissachatina fulica
3.2.1.B23
?
x * 77000
Bifidobacterium breve
3.2.1.B23
?
x * 79000
Pseudonocardia sp.
3.2.1.B23
?
x * 81000
Bifidobacterium longum
3.2.1.B23
?
x * 82000
Flavobacterium johnsoniae
3.2.1.B23
?
x * 85000
Mucilaginibacter sp. QM49
3.2.1.B23
?
x * 87000
Microbacterium esteraromaticum
3.2.1.B23
?
x * 90000
Passalora fulva
3.2.1.B23
?
x * 95000
Bifidobacterium longum
3.2.1.191
?
x * 51000
Sphingopyxis alaskensis
3.2.1.191
?
x * 49000
Sphingomonas sp.
3.2.1.191
?
x * 70000
Terrabacter ginsenosidimutans
3.2.1.191
?
x * 59000
Panax ginseng
3.2.1.193
?
x * 45000
Leuconostoc citreum
3.2.1.193
?
x * 45000
Pseudarthrobacter chlorophenolicus
3.2.1.193
?
x * 57000
Sulfolobus acidocaldarius
3.2.1.193
?
x * 57000
Saccharolobus solfataricus
3.2.1.193
?
x * 12000, native enzyme
Byssochlamys spectabilis
3.2.1.193
?
x * 74000
Aspergillus niger
3.2.1.193
?
x * 79000
Microbacterium esteraromaticum
3.2.1.194
?
x * 40000
Penicillium sclerotiorum
3.2.1.194
?
x * 56000
Aspergillus sp.
3.2.1.194
?
x * 53000
Absidia sp. (in: Fungi)
3.2.1.194
?
x * 59000
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
?
x * 54000
Pyrococcus furiosus
3.2.1.194
?
x * 67000
Sanguibacter keddieii
3.2.1.194
?
x * 85000
Fusarium subglutinans
3.2.1.194
?
x * 93000
Aspergillus niger
3.2.1.195
?
x * 65000
Actinosynnema mirum
Synonyms
EC Number
Synonyms
Commentary
Organism
3.2.1.B23
alpha-L-arabinofuranosidase
-
Caldicellulosiruptor saccharolyticus
3.2.1.B23
alpha-L-arabinofuranosidase
-
Bifidobacterium longum
3.2.1.B23
alpha-L-arabinofuranosidase
-
Panax ginseng
3.2.1.B23
alpha-L-arabinofuranosidase
-
Leuconostoc sp.
3.2.1.B23
alpha-L-arabinofuranosidase
-
Rhodanobacter ginsenosidimutans
3.2.1.B23
alpha-L-arabinopyranosidase
-
Bifidobacterium breve
3.2.1.B23
alpha-L-arabinopyranosidase
-
Caldicellulosiruptor saccharolyticus
3.2.1.B23
alpha-L-arabinopyranosidase
-
Bifidobacterium longum
3.2.1.B23
beta-galactosidase
-
Caldicellulosiruptor saccharolyticus
3.2.1.B23
beta-glucosidase
-
Thermus thermophilus
3.2.1.B23
beta-glucosidase
-
Pseudonocardia sp.
3.2.1.B23
beta-glucosidase
-
Aspergillus sp.
3.2.1.B23
beta-glucosidase
-
Microbacterium esteraromaticum
3.2.1.B23
beta-glucosidase
-
Bifidobacterium longum
3.2.1.B23
beta-glucosidase
-
Lissachatina fulica
3.2.1.B23
beta-glucosidase
-
Pseudothermotoga thermarum
3.2.1.B23
beta-glucosidase
-
Flavobacterium johnsoniae
3.2.1.B23
beta-glucosidase
-
Mucilaginibacter sp. QM49
3.2.1.B23
beta-glucosidase GI
-
Passalora fulva
3.2.1.B23
beta-glucosidase GII
-
Passalora fulva
3.2.1.B23
ginsenosidase type II
-
Thermus thermophilus
3.2.1.B23
ginsenosidase type II
-
Aspergillus niger
3.2.1.B23
ginsenosidase type II
-
Pseudonocardia sp.
3.2.1.B23
ginsenosidase type II
-
Rhizobium sp.
3.2.1.B23
ginsenosidase type II
-
Bifidobacterium breve
3.2.1.B23
ginsenosidase type II
-
Trichoderma viride
3.2.1.B23
ginsenosidase type II
-
Aspergillus sp.
3.2.1.B23
ginsenosidase type II
-
Caldicellulosiruptor saccharolyticus
3.2.1.B23
ginsenosidase type II
-
Microbacterium esteraromaticum
3.2.1.B23
ginsenosidase type II
-
Bifidobacterium longum
3.2.1.B23
ginsenosidase type II
-
Lissachatina fulica
3.2.1.B23
ginsenosidase type II
-
Panax ginseng
3.2.1.B23
ginsenosidase type II
-
Passalora fulva
3.2.1.B23
ginsenosidase type II
-
Leuconostoc sp.
3.2.1.B23
ginsenosidase type II
-
Pseudothermotoga thermarum
3.2.1.B23
ginsenosidase type II
-
Flavobacterium johnsoniae
3.2.1.B23
ginsenosidase type II
-
Bifidobacterium choerinum
3.2.1.B23
ginsenosidase type II
-
Rhodanobacter ginsenosidimutans
3.2.1.B23
ginsenosidase type II
-
Mucilaginibacter sp. QM49
3.2.1.B23
ginsenosidase type II-i-1
-
Thermus thermophilus
3.2.1.B23
ginsenosidase type II-i-1
-
Trichoderma viride
3.2.1.B23
ginsenosidase type II-i-1
-
Aspergillus sp.
3.2.1.B23
ginsenosidase type II-i-1
-
Bifidobacterium longum
3.2.1.B23
ginsenosidase type II-i-1
-
Lissachatina fulica
3.2.1.B23
ginsenosidase type II-i-1
-
Passalora fulva
3.2.1.B23
ginsenosidase type II-i-1
-
Pseudothermotoga thermarum
3.2.1.B23
ginsenosidase type II-i-1
-
Flavobacterium johnsoniae
3.2.1.B23
ginsenosidase type II-i-2
-
Bifidobacterium breve
3.2.1.B23
ginsenosidase type II-i-2
-
Trichoderma viride
3.2.1.B23
ginsenosidase type II-i-2
-
Caldicellulosiruptor saccharolyticus
3.2.1.B23
ginsenosidase type II-i-2
-
Bifidobacterium longum
3.2.1.B23
ginsenosidase type II-i-2
-
Bifidobacterium choerinum
3.2.1.B23
ginsenosidase type II-i-4
-
Trichoderma viride
3.2.1.B23
ginsenosidase type II-i-4
-
Caldicellulosiruptor saccharolyticus
3.2.1.B23
ginsenosidase type II-i-4
-
Bifidobacterium longum
3.2.1.B23
ginsenosidase type II-i-4
-
Panax ginseng
3.2.1.B23
ginsenosidase type II-i-4
-
Leuconostoc sp.
3.2.1.B23
ginsenosidase type II-i-4
-
Rhodanobacter ginsenosidimutans
3.2.1.B23
ginsenosidase type II-ii
-
Aspergillus niger
3.2.1.B23
ginsenosidase type II-ii
-
Pseudonocardia sp.
3.2.1.B23
ginsenosidase type II-ii
-
Rhizobium sp.
3.2.1.B23
ginsenosidase type II-ii
-
Microbacterium esteraromaticum
3.2.1.B23
ginsenosidase type II-ii
-
Mucilaginibacter sp. QM49
3.2.1.191
beta-glucosidase
-
Sphingomonas sp.
3.2.1.191
beta-glucosidase
-
Panax ginseng
3.2.1.191
beta-glucosidase
-
Sphingopyxis alaskensis
3.2.1.191
beta-glucosidase
-
Esteya vermicola
3.2.1.191
ginsenosidase type III-ii
-
Aspergillus niger
3.2.1.191
ginsenosidase type III-ii
-
Fusarium sp.
3.2.1.191
ginsenosidase type III-ii
-
Sphingomonas sp.
3.2.1.191
ginsenosidase type III-ii
-
Fusarium proliferatum
3.2.1.191
ginsenosidase type III-ii
-
Panax ginseng
3.2.1.191
ginsenosidase type III-ii
-
Terrabacter ginsenosidimutans
3.2.1.191
ginsenosidase type III-ii
-
Sphingopyxis alaskensis
3.2.1.191
ginsenosidase type III-ii
-
Esteya vermicola
3.2.1.193
beta-glucosidase
-
Byssochlamys spectabilis
3.2.1.193
beta-glucosidase
-
Sulfolobus acidocaldarius
3.2.1.193
beta-glucosidase
-
Saccharolobus solfataricus
3.2.1.193
beta-glucosidase
-
Aspergillus sp.
3.2.1.193
beta-glucosidase
-
Microbacterium esteraromaticum
3.2.1.193
beta-glucosidase
-
Leuconostoc citreum
3.2.1.193
beta-glucosidase
-
Fusobacterium sp.
3.2.1.193
beta-glucosidase
-
Pseudarthrobacter chlorophenolicus
3.2.1.193
ginsenosidase type I
-
Aspergillus niger
3.2.1.193
ginsenosidase type I
-
Byssochlamys spectabilis
3.2.1.193
ginsenosidase type I
-
Sulfolobus acidocaldarius
3.2.1.193
ginsenosidase type I
-
Leuconostoc mesenteroides
3.2.1.193
ginsenosidase type I
-
Lactiplantibacillus pentosus
3.2.1.193
ginsenosidase type I
-
Saccharolobus solfataricus
3.2.1.193
ginsenosidase type I
-
Aspergillus oryzae
3.2.1.193
ginsenosidase type I
-
Aspergillus sp.
3.2.1.193
ginsenosidase type I
-
Microbacterium esteraromaticum
3.2.1.193
ginsenosidase type I
-
Citrus limon
3.2.1.193
ginsenosidase type I
-
Leuconostoc citreum
3.2.1.193
ginsenosidase type I
-
Fusobacterium sp.
3.2.1.193
ginsenosidase type I
-
Pseudarthrobacter chlorophenolicus
3.2.1.193
ginsenosidase type I
-
Intrasporangium sp.
3.2.1.193
ginsenosidase type I
-
Globisporangium irregulare
3.2.1.193
ginsenosidase type I
-
Nocardioides panaciterrulae
3.2.1.193
ginsenosidase type I
-
Companilactobacillus paralimentarius
3.2.1.193
ginsenosidase type I
-
Sphingomonas leidyi
3.2.1.193
ginsenosidase type-I
-
Aspergillus niger
3.2.1.194
alpha-L-rhamnosidase
-
Absidia sp. (in: Fungi)
3.2.1.194
beta-glucosidase
-
Pyrococcus furiosus
3.2.1.194
beta-glucosidase
-
Fusarium subglutinans
3.2.1.194
beta-glucosidase
-
Penicillium sclerotiorum
3.2.1.194
beta-glucosidase
-
Sanguibacter keddieii
3.2.1.194
beta-glycosidase
-
Aspergillus niger
3.2.1.194
beta-xylosidase
-
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
ginsenosidase type IV
-
Aspergillus sp.
3.2.1.194
ginsenosidase type IV-i-1
-
Aspergillus niger
3.2.1.194
ginsenosidase type IV-i-1
-
Pyrococcus furiosus
3.2.1.194
ginsenosidase type IV-i-2
-
Pyrococcus furiosus
3.2.1.194
ginsenosidase type IV-i-2
-
Absidia sp. (in: Fungi)
3.2.1.194
ginsenosidase type IV-i-3
-
Pyrococcus furiosus
3.2.1.194
ginsenosidase type IV-i-3
-
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
ginsenosidase type IV-ii
-
Aspergillus sp.
3.2.1.194
ginsenosidase type IV-ii
-
Penicillium decumbens
3.2.1.194
ginsenosidase type IV-ii
-
Fusarium subglutinans
3.2.1.194
ginsenosidase type IV-ii
-
Penicillium sclerotiorum
3.2.1.194
ginsenosidase type IV-ii
-
Sanguibacter keddieii
3.2.1.195
beta-glucosidase
-
Penicillium sp.
3.2.1.195
beta-glucosidase
-
Actinosynnema mirum
3.2.1.195
ginsenosidase type V
-
Penicillium sp.
3.2.1.195
ginsenosidase type V
-
Actinosynnema mirum
Temperature Optimum [°C]
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
3.2.1.B23
30
-
-
Mucilaginibacter sp. QM49
3.2.1.B23
35
-
-
Bifidobacterium longum
3.2.1.B23
37
-
-
Pseudonocardia sp.
3.2.1.B23
37
-
-
Bifidobacterium breve
3.2.1.B23
37
-
-
Bifidobacterium longum
3.2.1.B23
37
-
-
Leuconostoc sp.
3.2.1.B23
37
-
-
Flavobacterium johnsoniae
3.2.1.B23
37
-
-
Rhodanobacter ginsenosidimutans
3.2.1.B23
40
-
-
Microbacterium esteraromaticum
3.2.1.B23
45
-
-
Passalora fulva
3.2.1.B23
50
-
-
Aspergillus sp.
3.2.1.B23
50
-
-
Panax ginseng
3.2.1.B23
70
-
-
Lissachatina fulica
3.2.1.B23
80
-
-
Caldicellulosiruptor saccharolyticus
3.2.1.B23
90
-
-
Thermus thermophilus
3.2.1.B23
90
-
-
Pseudothermotoga thermarum
3.2.1.191
37
-
-
Sphingomonas sp.
3.2.1.191
37
-
-
Terrabacter ginsenosidimutans
3.2.1.191
40
-
-
Sphingopyxis alaskensis
3.2.1.191
50
-
-
Esteya vermicola
3.2.1.191
60
-
-
Panax ginseng
3.2.1.193
37
-
-
Leuconostoc citreum
3.2.1.193
37
-
-
Pseudarthrobacter chlorophenolicus
3.2.1.193
40
-
-
Microbacterium esteraromaticum
3.2.1.193
45
-
-
Aspergillus niger
3.2.1.193
60
-
-
Byssochlamys spectabilis
3.2.1.193
85
-
-
Sulfolobus acidocaldarius
3.2.1.193
90
-
-
Saccharolobus solfataricus
3.2.1.194
25
-
-
Sanguibacter keddieii
3.2.1.194
37
-
-
Aspergillus niger
3.2.1.194
40
-
-
Aspergillus sp.
3.2.1.194
40
-
-
Absidia sp. (in: Fungi)
3.2.1.194
50
-
-
Fusarium subglutinans
3.2.1.194
60
-
-
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
65
-
-
Penicillium sclerotiorum
3.2.1.194
95
-
-
Pyrococcus furiosus
3.2.1.195
37
-
-
Actinosynnema mirum
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.2.1.B23
4.7
-
-
Bifidobacterium longum
3.2.1.B23
4.8
-
-
Pseudothermotoga thermarum
3.2.1.B23
5
-
-
Aspergillus sp.
3.2.1.B23
5
-
-
Panax ginseng
3.2.1.B23
5.5
-
-
Bifidobacterium breve
3.2.1.B23
5.5
-
-
Caldicellulosiruptor saccharolyticus
3.2.1.B23
5.5
-
-
Bifidobacterium longum
3.2.1.B23
5.5
-
-
Passalora fulva
3.2.1.B23
5.6
-
-
Lissachatina fulica
3.2.1.B23
6
-
-
Caldicellulosiruptor saccharolyticus
3.2.1.B23
6
-
-
Passalora fulva
3.2.1.B23
6
-
-
Leuconostoc sp.
3.2.1.B23
6
-
-
Flavobacterium johnsoniae
3.2.1.B23
6.5
-
-
Thermus thermophilus
3.2.1.B23
6.8
-
-
Bifidobacterium longum
3.2.1.B23
7
-
-
Pseudonocardia sp.
3.2.1.B23
7
-
-
Microbacterium esteraromaticum
3.2.1.B23
7.5
-
-
Rhodanobacter ginsenosidimutans
3.2.1.B23
8
-
-
Mucilaginibacter sp. QM49
3.2.1.191
5
-
-
Sphingomonas sp.
3.2.1.191
5
-
-
Panax ginseng
3.2.1.191
5
-
-
Esteya vermicola
3.2.1.191
5.5
-
-
Sphingopyxis alaskensis
3.2.1.191
7
-
-
Terrabacter ginsenosidimutans
3.2.1.193
3.5
-
-
Byssochlamys spectabilis
3.2.1.193
5
-
-
Aspergillus niger
3.2.1.193
5.5
-
-
Sulfolobus acidocaldarius
3.2.1.193
5.5
-
-
Saccharolobus solfataricus
3.2.1.193
6
-
-
Leuconostoc citreum
3.2.1.193
6
-
-
Pseudarthrobacter chlorophenolicus
3.2.1.193
7
-
-
Microbacterium esteraromaticum
3.2.1.194
4.5
-
-
Penicillium sclerotiorum
3.2.1.194
5
-
-
Absidia sp. (in: Fungi)
3.2.1.194
5.5
-
-
Pyrococcus furiosus
3.2.1.194
6
-
-
Aspergillus sp.
3.2.1.194
6
-
-
Fusarium subglutinans
3.2.1.194
6.5
-
-
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
7.5
-
-
Aspergillus niger
3.2.1.194
8
-
-
Sanguibacter keddieii
3.2.1.195
7
-
-
Actinosynnema mirum
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
3.2.1.B23
ginsenoside C-K + H2O
Rhizobium sp.
-
protopanaxadiol + D-glucose
-
-
?
3.2.1.B23
ginsenoside C-O + H2O
Bifidobacterium choerinum
-
ginsenoside F2 + L-arabinopyranose
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
Thermus thermophilus
-
ginsenoside F2 + D-glucose
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
Bifidobacterium longum
-
ginsenoside F2 + D-glucose
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
Flavobacterium johnsoniae
-
ginsenoside F2 + D-glucose
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
Bifidobacterium longum H-1
-
ginsenoside F2 + D-glucose
-
-
?
3.2.1.B23
ginsenoside G75 + H2O
Thermus thermophilus
-
ginsenoside C-K + D-glucose
-
-
?
3.2.1.B23
ginsenoside Mc + H2O
Caldicellulosiruptor saccharolyticus
-
ginsenoside C-K + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Mc + H2O
Rhodanobacter ginsenosidimutans
-
ginsenoside C-K + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Mc1 + H2O
Rhodanobacter ginsenosidimutans
-
ginsenoside F2 + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Thermus thermophilus
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Trichoderma viride
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Aspergillus sp.
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Bifidobacterium longum
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Lissachatina fulica
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Passalora fulva
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Pseudothermotoga thermarum
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Flavobacterium johnsoniae
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Aspergillus niger
-
ginsenoside Rg3 + 2 D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Pseudonocardia sp.
-
ginsenoside Rg3 + 2 D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Microbacterium esteraromaticum
-
ginsenoside Rg3 + 2 D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Bifidobacterium longum H-1
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
Pseudothermotoga thermarum DSM 5069T
-
ginsenoside Rd + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
Trichoderma viride
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
Bifidobacterium longum
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
Bifidobacterium choerinum
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
Microbacterium esteraromaticum
-
ginsenoside Rg3 + D-glucose + L-arabinopyranose
-
-
?
3.2.1.B23
ginsenoside Rb3 + H2O
Pseudonocardia sp.
-
ginsenoside Rg3 + D-glucose + D-xylose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Bifidobacterium breve
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Trichoderma viride
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Caldicellulosiruptor saccharolyticus
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Bifidobacterium longum
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Panax ginseng
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Leuconostoc sp.
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Rhodanobacter ginsenosidimutans
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
Bifidobacterium longum H-1
-
ginsenoside Rd + L-arabinofuranose
-
-
?
3.2.1.B23
ginsenoside Rd + H2O
Pseudonocardia sp.
-
ginsenoside Rg3 + D-glucose
-
-
?
3.2.1.B23
ginsenoside Re + H2O
Mucilaginibacter sp. QM49
-
ginsenoside Rg2 + D-glucose
-
-
?
3.2.1.B23
ginsenoside Rg1 + H2O
Mucilaginibacter sp. QM49
-
ginsenoside Rh1 + D-glucose
-
-
?
3.2.1.B23
additional information
Thermus thermophilus
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Trichoderma viride
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Aspergillus sp.
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Bifidobacterium longum
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Lissachatina fulica
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Passalora fulva
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Pseudothermotoga thermarum
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Flavobacterium johnsoniae
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Bifidobacterium breve
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
?
-
-
?
3.2.1.B23
additional information
Trichoderma viride
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
?
-
-
?
3.2.1.B23
additional information
Caldicellulosiruptor saccharolyticus
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
?
-
-
?
3.2.1.B23
additional information
Bifidobacterium longum
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
?
-
-
?
3.2.1.B23
additional information
Bifidobacterium choerinum
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
?
-
-
?
3.2.1.B23
additional information
Bifidobacterium longum H-1
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.B23
additional information
Bifidobacterium longum H-1
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
?
-
-
?
3.2.1.B23
additional information
Pseudothermotoga thermarum DSM 5069T
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
?
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
Sphingomonas sp.
-
ginsenoside G17 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
Sphingopyxis alaskensis
-
ginsenoside G17 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
Esteya vermicola
via ginsenoside G17
ginsenoside G75 + 2 D-glucose
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
Esteya vermicola CNU120806
via ginsenoside G17
ginsenoside G75 + 2 D-glucose
-
-
?
3.2.1.191
ginsenoside Rb2 + H2O
Sphingomonas sp.
-
ginsenoside C-O + D-glucose
-
-
?
3.2.1.191
ginsenoside Rb2 + H2O
Sphingopyxis alaskensis
-
ginsenoside C-O + D-glucose
-
-
?
3.2.1.191
ginsenoside Rc + H2O
Sphingomonas sp.
-
ginsenoside C-Mc1 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rc + H2O
Sphingopyxis alaskensis
-
ginsenoside C-Mc1 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rd + H2O
Esteya vermicola
via ginsenosside F2
ginsenoside C-K + 2 D-glucose
-
-
?
3.2.1.191
ginsenoside Rd + H2O
Sphingomonas sp.
-
ginsenoside F2 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rd + H2O
Sphingopyxis alaskensis
-
ginsenoside F2 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rd + H2O
Esteya vermicola CNU120806
via ginsenosside F2
ginsenoside C-K + 2 D-glucose
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
Fusarium sp.
-
ginsenoside Rh2 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
Fusarium proliferatum
-
ginsenoside Rh2 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
Panax ginseng
-
ginsenoside Rh2 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
Sphingopyxis alaskensis
-
ginsenoside Rh2 + D-glucose
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
Fusarium proliferatum ECU2042
-
ginsenoside Rh2 + D-glucose
-
-
?
3.2.1.191
additional information
Aspergillus niger
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Fusarium sp.
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Sphingomonas sp.
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Fusarium proliferatum
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Panax ginseng
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Terrabacter ginsenosidimutans
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Sphingopyxis alaskensis
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Esteya vermicola
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Esteya vermicola CNU120806
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.191
additional information
Fusarium proliferatum ECU2042
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
?
-
-
?
3.2.1.193
ginsenoside F2 + H2O
Sphingomonas leidyi
-
ginsenoside C-K + D-glucose
-
-
?
3.2.1.193
ginsenoside F2 + H2O
Aspergillus oryzae
-
ginsenoside C-K + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Saccharolobus solfataricus
via ginsenoside F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Aspergillus sp.
via ginsenoside F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Leuconostoc citreum
via ginsenoside F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Sulfolobus acidocaldarius
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Leuconostoc mesenteroides
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Lactiplantibacillus pentosus
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Microbacterium esteraromaticum
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Fusobacterium sp.
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Companilactobacillus paralimentarius
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Sphingomonas leidyi
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Aspergillus niger
via ginsenosides Rd and F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Aspergillus oryzae
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Pseudarthrobacter chlorophenolicus
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Intrasporangium sp.
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Globisporangium irregulare
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Nocardioides panaciterrulae
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Sphingomonas leidyi
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Byssochlamys spectabilis
-
ginsenoside Rg3 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Citrus limon
-
ginsenoside Rg3 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Aspergillus sp.
via ginsenoside F2
ginsenoside Rh2 + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Byssochlamys spectabilis 229-7
-
ginsenoside Rg3 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Lactiplantibacillus pentosus 6105
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Intrasporangium sp. GS603
-
ginsenoside F2 + 2 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Leuconostoc mesenteroides DC102
via ginsenosides F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Leuconostoc citreum LH1
via ginsenoside F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
Aspergillus niger g.848
via ginsenosides Rd and F2
ginsenoside C-K + 3 D-glucose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Aspergillus oryzae
-
ginsenoside F2 + D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Pseudarthrobacter chlorophenolicus
-
ginsenoside F2 + D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Globisporangium irregulare
-
ginsenoside F2 + D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Sulfolobus acidocaldarius
-
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Microbacterium esteraromaticum
-
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Saccharolobus solfataricus
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Aspergillus sp.
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Aspergillus niger
via ginsenosides Rd and F2
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Citrus limon
-
ginsenoside Rg3 + D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Aspergillus sp.
via ginsenoside F2
ginsenoside Rh2 + 2 D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
Aspergillus niger g.848
via ginsenosides Rd and F2
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
?
3.2.1.193
ginsenoside Rb3 + H2O
Aspergillus niger
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + xylose
-
-
?
3.2.1.193
ginsenoside Rb3 + H2O
Aspergillus niger g.848
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + xylose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Aspergillus oryzae
-
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Pseudarthrobacter chlorophenolicus
-
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Globisporangium irregulare
-
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Nocardioides panaciterrulae
-
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Aspergillus niger
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Saccharolobus solfataricus
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Aspergillus sp.
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Citrus limon
-
ginsenoside Rg3 + D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Aspergillus sp.
via ginsenoside F2
ginsenoside Rh2 + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rc + H2O
Aspergillus niger g.848
via ginsenoside F2
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
?
3.2.1.193
ginsenoside Rd + H2O
Byssochlamys spectabilis
-
ginsenoside Rg3 + D-glucose
-
-
?
3.2.1.193
ginsenoside Rd + H2O
Byssochlamys spectabilis 229-7
-
ginsenoside Rg3 + D-glucose
-
-
?
3.2.1.193
additional information
Aspergillus niger
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Byssochlamys spectabilis
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Sulfolobus acidocaldarius
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Leuconostoc mesenteroides
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Lactiplantibacillus pentosus
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Saccharolobus solfataricus
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Aspergillus oryzae
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Aspergillus sp.
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Microbacterium esteraromaticum
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Citrus limon
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Leuconostoc citreum
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Fusobacterium sp.
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Pseudarthrobacter chlorophenolicus
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Intrasporangium sp.
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Globisporangium irregulare
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Nocardioides panaciterrulae
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Companilactobacillus paralimentarius
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Sphingomonas leidyi
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Byssochlamys spectabilis 229-7
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Lactiplantibacillus pentosus 6105
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Intrasporangium sp. GS603
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Leuconostoc mesenteroides DC102
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Leuconostoc citreum LH1
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.193
additional information
Aspergillus niger g.848
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
?
-
-
?
3.2.1.194
ginsenoside R1 + H2O
Aspergillus sp.
-
ginsenoside F1 + D-glucose + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Re + H2O
Pyrococcus furiosus
-
ginsenoside Rg1 + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Re + H2O
Aspergillus sp.
-
ginsenoside F1 + D-glucose + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Re + H2O
Penicillium decumbens
-
ginsenoside F1 + D-glucose + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Rf + H2O
Aspergillus niger
-
ginsenoside Rh1 + D-glucose
-
-
?
3.2.1.194
ginsenoside Rf + H2O
Pyrococcus furiosus
-
ginsenoside Rh1 + D-glucose
-
-
?
3.2.1.194
ginsenoside Rf + H2O
Aspergillus sp.
-
protopanaxatriol + 2 D-glucose
-
-
?
3.2.1.194
ginsenoside Rf + H2O
Penicillium decumbens
-
protopanaxatriol + 2 D-glucose
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
Penicillium decumbens
-
ginsenoside F1 + D-glucose
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
Fusarium subglutinans
-
ginsenoside F1 + D-glucose
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
Penicillium sclerotiorum
-
ginsenoside F1 + D-glucose
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
Sanguibacter keddieii
-
ginsenoside F1 + D-glucose
-
-
?
3.2.1.194
ginsenoside Rg2 + 2 H2O
Penicillium decumbens
-
protopanaxatriol + D-glucose + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
Pyrococcus furiosus
-
ginsenoside Rh1 + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
Thermoanaerobacterium thermosaccharolyticum
-
ginsenoside Rh1 + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
Absidia sp. (in: Fungi)
-
ginsenoside Rh1 + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
Aspergillus sp.
-
protopanaxatriol + D-glucose + L-rhamnose
-
-
?
3.2.1.194
ginsenoside Rh1 + H2O
Penicillium decumbens
-
protopanaxatriol + D-glucose
-
-
?
3.2.1.194
additional information
Pyrococcus furiosus
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1
?
-
-
?
3.2.1.194
additional information
Aspergillus niger
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1. This conversion has been conducted by beta-glycosidase from Aspergillus niger
?
-
-
?
3.2.1.194
additional information
Absidia sp. (in: Fungi)
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2
?
-
-
?
3.2.1.194
additional information
Pyrococcus furiosus
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2. This conversion was performed using b-glycosidase from Pyrococcus furiosus
?
-
-
?
3.2.1.194
additional information
Pyrococcus furiosus
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
?
-
-
?
3.2.1.194
additional information
Thermoanaerobacterium thermosaccharolyticum
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
?
-
-
?
3.2.1.194
additional information
Penicillium decumbens
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
?
-
-
?
3.2.1.194
additional information
Fusarium subglutinans
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
?
-
-
?
3.2.1.194
additional information
Penicillium sclerotiorum
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
?
-
-
?
3.2.1.194
additional information
Sanguibacter keddieii
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
?
-
-
?
3.2.1.194
additional information
Aspergillus sp.
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-ii enzymes convert ginsenosides Rg1 and Rh1, containing only the inner glucose without the outer sugar at C-6, are converted to ginsenosides F1 and aglycone protopanaxatriol (APPT), respectively, by hydrolyzing the inner glucose linked to C-6 but not the glucose linked to C-20 in the PPT-type ginsenosides with the hydrolysis pattern of F. Ginsenosidase type IV-ii enzymes also hydrolyze the outer glucose of ginsenoside Rf, which has the outer and inner glucose at C-6 with the hydrolysis pattern of E-1; the outer rhamnose of ginsenosides Re and Rg2, which have the outer rhamnose and inner glucose at C-6 with the hydrolysis attern of E-2, and the outer xylose of notoginsenosides R1 and R2, which contain the outer xylose and inner glucose at C-6 with the hydrolysis pattern of E-3
?
-
-
?
3.2.1.194
notoginsenoside R1 + H2O
Pyrococcus furiosus
-
ginsenoside Rg1 + D-xylose
-
-
?
3.2.1.194
notoginsenoside R1 + H2O
Thermoanaerobacterium thermosaccharolyticum
-
ginsenoside Rg1 + D-xylose
-
-
?
3.2.1.195
ginsenoside Re + H2O
Penicillium sp.
-
ginsenoside Rh1 + D-glucose + L-rhamnose
-
-
?
3.2.1.195
ginsenoside Re + H2O
Actinosynnema mirum
-
ginsenoside Rh1 + D-glucose + L-rhamnose
-
-
?
3.2.1.195
ginsenoside Rg1 + H2O
Penicillium sp.
via ginsenoside Rh1
protopanaxatriol + 2 D-glucose
-
-
?
3.2.1.195
ginsenoside Rg1 + H2O
Actinosynnema mirum
via ginsenoside Rh1
protopanaxatriol + 2 D-glucose
-
-
?
3.2.1.195
additional information
Penicillium sp.
ginsenosidase type V enzymes hydrolyze the sugars linked to C-20 and C-6 in the PPD-type ginsenosides with the hydrolysis patterns of B, E and F. Crude enzyme from Penicillium sp. and beta-glucosidase from Actinosynnema mirum convert ginsenosides Re and Rg1 to Rh1 and APPT, respectively
?
-
-
?
3.2.1.195
additional information
Actinosynnema mirum
ginsenosidase type V enzymes hydrolyze the sugars linked to C-20 and C-6 in the PPD-type ginsenosides with the hydrolysis patterns of B, E and F. Crude enzyme from Penicillium sp. and beta-glucosidase from Actinosynnema mirum convert ginsenosides Re and Rg1 to Rh1 and APPT, respectively
?
-
-
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
3.2.1.191
native enzyme
Esteya vermicola
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
3.2.1.B23
3
-
pH 5.0, 50°C
Panax ginseng
3.2.1.B23
4
-
pH 8.0, 30°C
Mucilaginibacter sp. QM49
3.2.1.B23
5
-
pH 6.5, 90°C
Thermus thermophilus
3.2.1.B23
8
-
pH 6.8, 37°C
Bifidobacterium longum
3.2.1.B23
9
-
pH 5.5, 37°C
Bifidobacterium breve
3.2.1.B23
15
-
pH 7.5, 37°C
Rhodanobacter ginsenosidimutans
3.2.1.B23
18
-
pH 6.0, 45°C
Passalora fulva
3.2.1.B23
22
-
pH 5.5, 35°C
Bifidobacterium longum
3.2.1.B23
24
-
pH 5.5, 45°C
Passalora fulva
3.2.1.B23
26
-
pH 6.0, 37°C
Leuconostoc sp.
3.2.1.B23
28
-
pH 5.5, 80°C
Caldicellulosiruptor saccharolyticus
3.2.1.B23
40
-
pH 7.0, 37°C
Pseudonocardia sp.
3.2.1.B23
61
-
pH 7.0, 40°C
Microbacterium esteraromaticum
3.2.1.B23
67
-
pH 4.7, 37°C
Bifidobacterium longum
3.2.1.B23
140
-
pH 4.8, 90°C
Pseudothermotoga thermarum
3.2.1.B23
250
-
pH 5.6, 70°C
Lissachatina fulica
3.2.1.191
2
-
pH 5.0, 60°C, substrate ginsenoside Rg3
Panax ginseng
3.2.1.191
76
-
purified enzyme, pH 7.0, 37°C
Terrabacter ginsenosidimutans
3.2.1.191
290
-
purified native enzyme, pH 5.0, 50°C
Esteya vermicola
3.2.1.191
309
-
pH 5.5, 40°C
Sphingopyxis alaskensis
3.2.1.193
29
-
pH 7.0, 40°C
Microbacterium esteraromaticum
3.2.1.193
137
-
pH 3.5, 60°C
Byssochlamys spectabilis
3.2.1.193
2020
-
pH 5.5, 90°C
Saccharolobus solfataricus
3.2.1.194
1
-
pH 5.0, 40°C
Absidia sp. (in: Fungi)
3.2.1.194
2
-
pH 5.5, 95°C
Pyrococcus furiosus
3.2.1.194
2
-
substrate ginsenoside Rf, pH 6.0, 40°C
Aspergillus sp.
3.2.1.194
4
-
substrate ginsenoside Rf, pH 7.5, 37°C
Aspergillus niger
3.2.1.194
4.5
-
pH 6.5, 60°C
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
136
-
pH 6.0, 50°C
Fusarium subglutinans
3.2.1.194
136
-
pH 6.0, 50°C
Penicillium sclerotiorum
3.2.1.194
912
-
pH 6.0, 40°C
Pyrococcus furiosus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
3.2.1.B23
ginsenoside C-K + H2O
-
753334
Rhizobium sp.
protopanaxadiol + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside C-O + H2O
-
753334
Bifidobacterium choerinum
ginsenoside F2 + L-arabinopyranose
-
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
-
753334
Thermus thermophilus
ginsenoside F2 + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
-
753334
Bifidobacterium longum
ginsenoside F2 + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
-
753334
Flavobacterium johnsoniae
ginsenoside F2 + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside G17 + H2O
-
753334
Bifidobacterium longum H-1
ginsenoside F2 + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside G75 + H2O
-
753334
Thermus thermophilus
ginsenoside C-K + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Mc + H2O
-
753334
Caldicellulosiruptor saccharolyticus
ginsenoside C-K + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Mc + H2O
-
753334
Rhodanobacter ginsenosidimutans
ginsenoside C-K + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Mc1 + H2O
-
753334
Rhodanobacter ginsenosidimutans
ginsenoside F2 + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Thermus thermophilus
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Trichoderma viride
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Aspergillus sp.
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Bifidobacterium longum
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Lissachatina fulica
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Passalora fulva
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Pseudothermotoga thermarum
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Flavobacterium johnsoniae
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Bifidobacterium longum H-1
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Pseudothermotoga thermarum DSM 5069T
ginsenoside Rd + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Aspergillus niger
ginsenoside Rg3 + 2 D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Pseudonocardia sp.
ginsenoside Rg3 + 2 D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb1 + H2O
-
753334
Microbacterium esteraromaticum
ginsenoside Rg3 + 2 D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
-
753334
Trichoderma viride
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
-
753334
Bifidobacterium longum
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
-
753334
Bifidobacterium choerinum
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rb2 + H2O
-
753334
Microbacterium esteraromaticum
ginsenoside Rg3 + D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.B23
ginsenoside Rb3 + H2O
-
753334
Pseudonocardia sp.
ginsenoside Rg3 + D-glucose + D-xylose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Bifidobacterium breve
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Trichoderma viride
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Caldicellulosiruptor saccharolyticus
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Bifidobacterium longum
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Panax ginseng
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Leuconostoc sp.
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Rhodanobacter ginsenosidimutans
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rc + H2O
-
753334
Bifidobacterium longum H-1
ginsenoside Rd + L-arabinofuranose
-
-
-
?
3.2.1.B23
ginsenoside Rd + H2O
-
753334
Pseudonocardia sp.
ginsenoside Rg3 + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Re + H2O
-
753334
Mucilaginibacter sp. QM49
ginsenoside Rg2 + D-glucose
-
-
-
?
3.2.1.B23
ginsenoside Rg1 + H2O
-
753334
Mucilaginibacter sp. QM49
ginsenoside Rh1 + D-glucose
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Thermus thermophilus
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Trichoderma viride
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Aspergillus sp.
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Bifidobacterium longum
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Lissachatina fulica
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Passalora fulva
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Pseudothermotoga thermarum
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Flavobacterium johnsoniae
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
753334
Bifidobacterium breve
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
753334
Trichoderma viride
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
753334
Caldicellulosiruptor saccharolyticus
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
753334
Bifidobacterium longum
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
753334
Bifidobacterium choerinum
?
-
-
-
?
3.2.1.B23
additional information
hydrolysis of the C-20 inner Glc
753334
Aspergillus niger
?
-
-
-
?
3.2.1.B23
additional information
hydrolysis of the C-20 inner Glc
753334
Pseudonocardia sp.
?
-
-
-
?
3.2.1.B23
additional information
hydrolysis of the C-20 inner Glc
753334
Rhizobium sp.
?
-
-
-
?
3.2.1.B23
additional information
hydrolysis of the C-20 inner Glc
753334
Microbacterium esteraromaticum
?
-
-
-
?
3.2.1.B23
additional information
hydrolysis of the C-20 inner Glc
753334
Mucilaginibacter sp. QM49
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Bifidobacterium longum H-1
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
753334
Bifidobacterium longum H-1
?
-
-
-
?
3.2.1.B23
additional information
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1)
753334
Pseudothermotoga thermarum DSM 5069T
?
-
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
-
753334
Sphingomonas sp.
ginsenoside G17 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
-
753334
Sphingopyxis alaskensis
ginsenoside G17 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
via ginsenoside G17
753334
Terrabacter ginsenosidimutans
ginsenoside G75 + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
via ginsenoside G17
753334
Esteya vermicola
ginsenoside G75 + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb1 + H2O
via ginsenoside G17
753334
Esteya vermicola CNU120806
ginsenoside G75 + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb2 + H2O
-
753334
Sphingomonas sp.
ginsenoside C-O + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb2 + H2O
-
753334
Sphingopyxis alaskensis
ginsenoside C-O + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb2 + H2O
via ginsenoside C-O
753334
Terrabacter ginsenosidimutans
ginsenoside C-Y + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rb3 + H2O
via ginsenoside C-Mx1
753334
Terrabacter ginsenosidimutans
ginsenoside C-Mx + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rc + H2O
-
753334
Sphingomonas sp.
ginsenoside C-Mc1 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rc + H2O
-
753334
Sphingopyxis alaskensis
ginsenoside C-Mc1 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rc + H2O
via ginsenoside C-Mc1
753334
Terrabacter ginsenosidimutans
ginsenoside C-Mc + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
via ginsenoside F2
753334
Esteya vermicola
ginsenoside C-K + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
via ginsenosside F2
753334
Terrabacter ginsenosidimutans
ginsenoside C-K + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
via ginsenosside F2
753334
Esteya vermicola
ginsenoside C-K + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
via ginsenoside F2
753334
Esteya vermicola CNU120806
ginsenoside C-K + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
via ginsenosside F2
753334
Esteya vermicola CNU120806
ginsenoside C-K + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
-
753334
Sphingomonas sp.
ginsenoside F2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rd + H2O
-
753334
Sphingopyxis alaskensis
ginsenoside F2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
-
753334
Fusarium sp.
ginsenoside Rh2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
-
753334
Fusarium proliferatum
ginsenoside Rh2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
-
753334
Panax ginseng
ginsenoside Rh2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
-
753334
Sphingopyxis alaskensis
ginsenoside Rh2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
-
753334
Fusarium proliferatum ECU2042
ginsenoside Rh2 + D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
via ginsenoside Rh2
753334
Terrabacter ginsenosidimutans
protopanaxadiol aglycone + 2 D-glucose
-
-
-
?
3.2.1.191
ginsenoside Rg3 + H2O
via ginsenoside Rh2, hydrolysis of the inner glucose at C-3
753334
Aspergillus niger
protopanaxadiol aglycone + 2 D-glucose
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Aspergillus niger
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Fusarium sp.
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Sphingomonas sp.
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Fusarium proliferatum
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Panax ginseng
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Terrabacter ginsenosidimutans
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Sphingopyxis alaskensis
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Esteya vermicola
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Aspergillus niger
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Fusarium sp.
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Sphingomonas sp.
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Fusarium proliferatum
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Panax ginseng
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Terrabacter ginsenosidimutans
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Esteya vermicola
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides. beta-Glucosidase from Sphingopyxis alaskensis hydrolyzes only the outer glucose at C-3 in ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to product G17, C-O, C-Mc1, F2 and Rh2, respectively, without further hydrolysis
753334
Sphingopyxis alaskensis
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Esteya vermicola CNU120806
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Esteya vermicola CNU120806
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III are classified into types III-i and III-ii, which hydrolyze the outer glucose and inner glucose linked to C-3 in the PPD-type ginsenosides, respectively. Ginsenosidase type III-i converts ginsenosides Rb1, Rb2, Rc, Rd and Rg3 to G17, C-O, C-Mc1, F2 and Rh2, respectively, by hydrolyzing only the outer glucose linked to C-3 in the PPD-type ginsenosides
753334
Fusarium proliferatum ECU2042
?
-
-
-
?
3.2.1.191
additional information
ginsenosidase type III-i catalyzes the hydrolysis of only C-3 outer glucose in PPD-type gindenosides. Ginsenosidase type III-ii catalyzes the hydrolysis of outer and inner, or only inner glucose in PPD-type ginsenosides
753334
Fusarium proliferatum ECU2042
?
-
-
-
?
3.2.1.193
ginsenoside F2 + H2O
-
753334
Sphingomonas leidyi
ginsenoside C-K + D-glucose
-
-
-
?
3.2.1.193
ginsenoside F2 + H2O
-
753334
Aspergillus oryzae
ginsenoside C-K + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenoside F2
753334
Saccharolobus solfataricus
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenoside F2
753334
Aspergillus sp.
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenoside F2
753334
Leuconostoc citreum
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Sulfolobus acidocaldarius
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Leuconostoc mesenteroides
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Lactiplantibacillus pentosus
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Microbacterium esteraromaticum
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Fusobacterium sp.
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Companilactobacillus paralimentarius
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Sphingomonas leidyi
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides Rd and F2
753334
Aspergillus niger
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Lactiplantibacillus pentosus 6105
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides F2
753334
Leuconostoc mesenteroides DC102
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenoside F2
753334
Leuconostoc citreum LH1
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenosides Rd and F2
753334
Aspergillus niger g.848
ginsenoside C-K + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Aspergillus oryzae
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Pseudarthrobacter chlorophenolicus
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Intrasporangium sp.
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Globisporangium irregulare
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Nocardioides panaciterrulae
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Sphingomonas leidyi
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Intrasporangium sp. GS603
ginsenoside F2 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Byssochlamys spectabilis
ginsenoside Rg3 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Citrus limon
ginsenoside Rg3 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
-
753334
Byssochlamys spectabilis 229-7
ginsenoside Rg3 + 2 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb1 + H2O
via ginsenoside F2
753334
Aspergillus sp.
ginsenoside Rh2 + 3 D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
-
753334
Aspergillus oryzae
ginsenoside F2 + D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
-
753334
Pseudarthrobacter chlorophenolicus
ginsenoside F2 + D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
-
753334
Globisporangium irregulare
ginsenoside F2 + D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
-
753334
Sulfolobus acidocaldarius
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
-
753334
Microbacterium esteraromaticum
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
via ginsenoside F2
753334
Saccharolobus solfataricus
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
via ginsenoside F2
753334
Aspergillus sp.
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
via ginsenosides Rd and F2
753334
Aspergillus niger
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
via ginsenosides Rd and F2
753334
Aspergillus niger g.848
ginsenoside C-K + 2 D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
-
753334
Citrus limon
ginsenoside Rg3 + D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb2 + H2O
via ginsenoside F2
753334
Aspergillus sp.
ginsenoside Rh2 + 2 D-glucose + L-arabinopyranose
-
-
-
?
3.2.1.193
ginsenoside Rb3 + H2O
via ginsenoside F2
753334
Aspergillus niger
ginsenoside C-K + 2 D-glucose + xylose
-
-
-
?
3.2.1.193
ginsenoside Rb3 + H2O
via ginsenoside F2
753334
Aspergillus niger g.848
ginsenoside C-K + 2 D-glucose + xylose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
-
753334
Aspergillus oryzae
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
-
753334
Pseudarthrobacter chlorophenolicus
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
-
753334
Globisporangium irregulare
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
-
753334
Nocardioides panaciterrulae
ginsenoside F2 + D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
via ginsenoside F2
753334
Aspergillus niger
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
via ginsenoside F2
753334
Saccharolobus solfataricus
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
via ginsenoside F2
753334
Aspergillus sp.
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
via ginsenoside F2
753334
Aspergillus niger g.848
ginsenoside C-K + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
-
753334
Citrus limon
ginsenoside Rg3 + D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rc + H2O
via ginsenoside F2
753334
Aspergillus sp.
ginsenoside Rh2 + 2 D-glucose + L-arabinofuranose
-
-
-
?
3.2.1.193
ginsenoside Rd + H2O
-
753334
Byssochlamys spectabilis
ginsenoside Rg3 + D-glucose
-
-
-
?
3.2.1.193
ginsenoside Rd + H2O
-
753334
Byssochlamys spectabilis 229-7
ginsenoside Rg3 + D-glucose
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Aspergillus niger
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Byssochlamys spectabilis
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Sulfolobus acidocaldarius
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Leuconostoc mesenteroides
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Lactiplantibacillus pentosus
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Saccharolobus solfataricus
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Aspergillus oryzae
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Aspergillus sp.
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Microbacterium esteraromaticum
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Citrus limon
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Leuconostoc citreum
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Fusobacterium sp.
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Pseudarthrobacter chlorophenolicus
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Intrasporangium sp.
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Globisporangium irregulare
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Nocardioides panaciterrulae
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Companilactobacillus paralimentarius
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Sphingomonas leidyi
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Byssochlamys spectabilis 229-7
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Lactiplantibacillus pentosus 6105
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Intrasporangium sp. GS603
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Leuconostoc mesenteroides DC102
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Leuconostoc citreum LH1
?
-
-
-
?
3.2.1.193
additional information
ginsenosidase type I enzymes simultaneously hydrolyze the sugars linked to C-20 and C-3 in the PPD-type ginsenosides and have broad hydrolysis patterns of A, B, C and D
753334
Aspergillus niger g.848
?
-
-
-
?
3.2.1.194
ginsenoside R1 + H2O
-
753334
Aspergillus sp.
ginsenoside F1 + D-glucose + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Re + H2O
-
753334
Pyrococcus furiosus
ginsenoside Rg1 + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Re + H2O
-
753334
Aspergillus sp.
ginsenoside F1 + D-glucose + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Re + H2O
-
753334
Penicillium decumbens
ginsenoside F1 + D-glucose + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Rf + H2O
-
753334
Aspergillus niger
ginsenoside Rh1 + D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rf + H2O
-
753334
Pyrococcus furiosus
ginsenoside Rh1 + D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rf + H2O
-
753334
Aspergillus sp.
protopanaxatriol + 2 D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rf + H2O
-
753334
Penicillium decumbens
protopanaxatriol + 2 D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
-
753334
Penicillium decumbens
ginsenoside F1 + D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
-
753334
Fusarium subglutinans
ginsenoside F1 + D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
-
753334
Penicillium sclerotiorum
ginsenoside F1 + D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rg1 + H2O
-
753334
Sanguibacter keddieii
ginsenoside F1 + D-glucose
-
-
-
?
3.2.1.194
ginsenoside Rg2 + 2 H2O
-
753334
Penicillium decumbens
protopanaxatriol + D-glucose + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
-
753334
Pyrococcus furiosus
ginsenoside Rh1 + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
-
753334
Thermoanaerobacterium thermosaccharolyticum
ginsenoside Rh1 + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
-
753334
Absidia sp. (in: Fungi)
ginsenoside Rh1 + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Rg2 + H2O
-
753334
Aspergillus sp.
protopanaxatriol + D-glucose + L-rhamnose
-
-
-
?
3.2.1.194
ginsenoside Rh1 + H2O
-
753334
Penicillium decumbens
protopanaxatriol + D-glucose
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1
753334
Pyrococcus furiosus
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1. This conversion has been conducted by beta-glycosidase from Aspergillus niger
753334
Aspergillus niger
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2
753334
Absidia sp. (in: Fungi)
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2. This conversion was performed using b-glycosidase from Pyrococcus furiosus
753334
Pyrococcus furiosus
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
753334
Pyrococcus furiosus
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
753334
Thermoanaerobacterium thermosaccharolyticum
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
753334
Penicillium decumbens
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
753334
Fusarium subglutinans
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
753334
Penicillium sclerotiorum
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
753334
Sanguibacter keddieii
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-ii enzymes convert ginsenosides Rg1 and Rh1, containing only the inner glucose without the outer sugar at C-6, are converted to ginsenosides F1 and aglycone protopanaxatriol (APPT), respectively, by hydrolyzing the inner glucose linked to C-6 but not the glucose linked to C-20 in the PPT-type ginsenosides with the hydrolysis pattern of F. Ginsenosidase type IV-ii enzymes also hydrolyze the outer glucose of ginsenoside Rf, which has the outer and inner glucose at C-6 with the hydrolysis pattern of E-1; the outer rhamnose of ginsenosides Re and Rg2, which have the outer rhamnose and inner glucose at C-6 with the hydrolysis attern of E-2, and the outer xylose of notoginsenosides R1 and R2, which contain the outer xylose and inner glucose at C-6 with the hydrolysis pattern of E-3
753334
Aspergillus sp.
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1. This conversion has been conducted by beta-glycosidase from Pyrococcus furiosus
753334
Pyrococcus furiosus
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2. This conversion is performed using beta-glycosidase from Pyrococcus furiosus
753334
Pyrococcus furiosus
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides. beta-Gglycosidase from Pyrococcus furiosus shows broad substrate specificity that hydrolyzes the outer residue glucose and rhamnose and xylose at C-6
753334
Pyrococcus furiosus
?
-
-
-
?
3.2.1.194
additional information
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides. beta-Xylosidase from Thermoanaerobacterium thermosaccharolyticum converts notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1 by selectively hydrolyzing only the outer xylose at C-6
753334
Thermoanaerobacterium thermosaccharolyticum
?
-
-
-
?
3.2.1.194
notoginsenoside R1 + H2O
-
753334
Pyrococcus furiosus
ginsenoside Rg1 + D-xylose
-
-
-
?
3.2.1.194
notoginsenoside R1 + H2O
-
753334
Thermoanaerobacterium thermosaccharolyticum
ginsenoside Rg1 + D-xylose
-
-
-
?
3.2.1.195
ginsenoside Re + H2O
-
753334
Penicillium sp.
ginsenoside Rh1 + D-glucose + L-rhamnose
-
-
-
?
3.2.1.195
ginsenoside Re + H2O
-
753334
Actinosynnema mirum
ginsenoside Rh1 + D-glucose + L-rhamnose
-
-
-
?
3.2.1.195
ginsenoside Rg1 + H2O
via ginsenoside Rh1
753334
Penicillium sp.
protopanaxatriol + 2 D-glucose
-
-
-
?
3.2.1.195
ginsenoside Rg1 + H2O
via ginsenoside Rh1
753334
Actinosynnema mirum
protopanaxatriol + 2 D-glucose
-
-
-
?
3.2.1.195
additional information
ginsenosidase type V enzymes hydrolyze the sugars linked to C-20 and C-6 in the PPD-type ginsenosides with the hydrolysis patterns of B, E and F. Crude enzyme from Penicillium sp. and beta-glucosidase from Actinosynnema mirum convert ginsenosides Re and Rg1 to Rh1 and APPT, respectively
753334
Penicillium sp.
?
-
-
-
?
3.2.1.195
additional information
ginsenosidase type V enzymes hydrolyze the sugars linked to C-20 and C-6 in the PPD-type ginsenosides with the hydrolysis patterns of B, E and F. Crude enzyme from Penicillium sp. and beta-glucosidase from Actinosynnema mirum convert ginsenosides Re and Rg1 to Rh1 and APPT, respectively
753334
Actinosynnema mirum
?
-
-
-
?
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
3.2.1.B23
?
x * 56000
Rhodanobacter ginsenosidimutans
3.2.1.B23
?
x * 57000
Bifidobacterium longum
3.2.1.B23
?
x * 57000
Pseudothermotoga thermarum
3.2.1.B23
?
x * 49000
Thermus thermophilus
3.2.1.B23
?
x * 58000
Caldicellulosiruptor saccharolyticus
3.2.1.B23
?
x * 58000
Leuconostoc sp.
3.2.1.B23
?
x * 80000
Caldicellulosiruptor saccharolyticus
3.2.1.B23
?
x * 80000
Passalora fulva
3.2.1.B23
?
x * 88000
Microbacterium esteraromaticum
3.2.1.B23
?
x * 60000
Aspergillus sp.
3.2.1.B23
?
x * 86000
Panax ginseng
3.2.1.B23
?
x * 120000
Lissachatina fulica
3.2.1.B23
?
x * 77000
Bifidobacterium breve
3.2.1.B23
?
x * 79000
Pseudonocardia sp.
3.2.1.B23
?
x * 81000
Bifidobacterium longum
3.2.1.B23
?
x * 82000
Flavobacterium johnsoniae
3.2.1.B23
?
x * 85000
Mucilaginibacter sp. QM49
3.2.1.B23
?
x * 87000
Microbacterium esteraromaticum
3.2.1.B23
?
x * 90000
Passalora fulva
3.2.1.B23
?
x * 95000
Bifidobacterium longum
3.2.1.191
?
x * 51000
Sphingopyxis alaskensis
3.2.1.191
?
x * 49000
Sphingomonas sp.
3.2.1.191
?
x * 70000
Terrabacter ginsenosidimutans
3.2.1.191
?
x * 59000
Panax ginseng
3.2.1.193
?
x * 45000
Leuconostoc citreum
3.2.1.193
?
x * 45000
Pseudarthrobacter chlorophenolicus
3.2.1.193
?
x * 57000
Sulfolobus acidocaldarius
3.2.1.193
?
x * 57000
Saccharolobus solfataricus
3.2.1.193
?
x * 12000, native enzyme
Byssochlamys spectabilis
3.2.1.193
?
x * 74000
Aspergillus niger
3.2.1.193
?
x * 79000
Microbacterium esteraromaticum
3.2.1.194
?
x * 40000
Penicillium sclerotiorum
3.2.1.194
?
x * 56000
Aspergillus sp.
3.2.1.194
?
x * 53000
Absidia sp. (in: Fungi)
3.2.1.194
?
x * 59000
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
?
x * 54000
Pyrococcus furiosus
3.2.1.194
?
x * 67000
Sanguibacter keddieii
3.2.1.194
?
x * 85000
Fusarium subglutinans
3.2.1.194
?
x * 93000
Aspergillus niger
3.2.1.195
?
x * 65000
Actinosynnema mirum
Temperature Optimum [°C] (protein specific)
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
3.2.1.B23
30
-
-
Mucilaginibacter sp. QM49
3.2.1.B23
35
-
-
Bifidobacterium longum
3.2.1.B23
37
-
-
Pseudonocardia sp.
3.2.1.B23
37
-
-
Bifidobacterium breve
3.2.1.B23
37
-
-
Bifidobacterium longum
3.2.1.B23
37
-
-
Leuconostoc sp.
3.2.1.B23
37
-
-
Flavobacterium johnsoniae
3.2.1.B23
37
-
-
Rhodanobacter ginsenosidimutans
3.2.1.B23
40
-
-
Microbacterium esteraromaticum
3.2.1.B23
45
-
-
Passalora fulva
3.2.1.B23
50
-
-
Aspergillus sp.
3.2.1.B23
50
-
-
Panax ginseng
3.2.1.B23
70
-
-
Lissachatina fulica
3.2.1.B23
80
-
-
Caldicellulosiruptor saccharolyticus
3.2.1.B23
90
-
-
Thermus thermophilus
3.2.1.B23
90
-
-
Pseudothermotoga thermarum
3.2.1.191
37
-
-
Sphingomonas sp.
3.2.1.191
37
-
-
Terrabacter ginsenosidimutans
3.2.1.191
40
-
-
Sphingopyxis alaskensis
3.2.1.191
50
-
-
Esteya vermicola
3.2.1.191
60
-
-
Panax ginseng
3.2.1.193
37
-
-
Leuconostoc citreum
3.2.1.193
37
-
-
Pseudarthrobacter chlorophenolicus
3.2.1.193
40
-
-
Microbacterium esteraromaticum
3.2.1.193
45
-
-
Aspergillus niger
3.2.1.193
60
-
-
Byssochlamys spectabilis
3.2.1.193
85
-
-
Sulfolobus acidocaldarius
3.2.1.193
90
-
-
Saccharolobus solfataricus
3.2.1.194
25
-
-
Sanguibacter keddieii
3.2.1.194
37
-
-
Aspergillus niger
3.2.1.194
40
-
-
Aspergillus sp.
3.2.1.194
40
-
-
Absidia sp. (in: Fungi)
3.2.1.194
50
-
-
Fusarium subglutinans
3.2.1.194
60
-
-
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
65
-
-
Penicillium sclerotiorum
3.2.1.194
95
-
-
Pyrococcus furiosus
3.2.1.195
37
-
-
Actinosynnema mirum
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.2.1.B23
4.7
-
-
Bifidobacterium longum
3.2.1.B23
4.8
-
-
Pseudothermotoga thermarum
3.2.1.B23
5
-
-
Aspergillus sp.
3.2.1.B23
5
-
-
Panax ginseng
3.2.1.B23
5.5
-
-
Bifidobacterium breve
3.2.1.B23
5.5
-
-
Caldicellulosiruptor saccharolyticus
3.2.1.B23
5.5
-
-
Bifidobacterium longum
3.2.1.B23
5.5
-
-
Passalora fulva
3.2.1.B23
5.6
-
-
Lissachatina fulica
3.2.1.B23
6
-
-
Caldicellulosiruptor saccharolyticus
3.2.1.B23
6
-
-
Passalora fulva
3.2.1.B23
6
-
-
Leuconostoc sp.
3.2.1.B23
6
-
-
Flavobacterium johnsoniae
3.2.1.B23
6.5
-
-
Thermus thermophilus
3.2.1.B23
6.8
-
-
Bifidobacterium longum
3.2.1.B23
7
-
-
Pseudonocardia sp.
3.2.1.B23
7
-
-
Microbacterium esteraromaticum
3.2.1.B23
7.5
-
-
Rhodanobacter ginsenosidimutans
3.2.1.B23
8
-
-
Mucilaginibacter sp. QM49
3.2.1.191
5
-
-
Sphingomonas sp.
3.2.1.191
5
-
-
Panax ginseng
3.2.1.191
5
-
-
Esteya vermicola
3.2.1.191
5.5
-
-
Sphingopyxis alaskensis
3.2.1.191
7
-
-
Terrabacter ginsenosidimutans
3.2.1.193
3.5
-
-
Byssochlamys spectabilis
3.2.1.193
5
-
-
Aspergillus niger
3.2.1.193
5.5
-
-
Sulfolobus acidocaldarius
3.2.1.193
5.5
-
-
Saccharolobus solfataricus
3.2.1.193
6
-
-
Leuconostoc citreum
3.2.1.193
6
-
-
Pseudarthrobacter chlorophenolicus
3.2.1.193
7
-
-
Microbacterium esteraromaticum
3.2.1.194
4.5
-
-
Penicillium sclerotiorum
3.2.1.194
5
-
-
Absidia sp. (in: Fungi)
3.2.1.194
5.5
-
-
Pyrococcus furiosus
3.2.1.194
6
-
-
Aspergillus sp.
3.2.1.194
6
-
-
Fusarium subglutinans
3.2.1.194
6.5
-
-
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
7.5
-
-
Aspergillus niger
3.2.1.194
8
-
-
Sanguibacter keddieii
3.2.1.195
7
-
-
Actinosynnema mirum
General Information
EC Number
General Information
Commentary
Organism
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Thermus thermophilus
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Pseudothermotoga thermarum
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 2, GH2
Microbacterium esteraromaticum
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Pseudonocardia sp.
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Microbacterium esteraromaticum
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Bifidobacterium longum
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Flavobacterium johnsoniae
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Mucilaginibacter sp. QM49
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 42, GH42
Caldicellulosiruptor saccharolyticus
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 51, GH51
Caldicellulosiruptor saccharolyticus
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 51, GH51
Bifidobacterium longum
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 51, GH51
Leuconostoc sp.
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 51, GH51
Rhodanobacter ginsenosidimutans
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
Trichoderma viride
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
Caldicellulosiruptor saccharolyticus
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
Bifidobacterium longum
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
Panax ginseng
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
Leuconostoc sp.
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
Rhodanobacter ginsenosidimutans
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
Bifidobacterium breve
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
Trichoderma viride
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
Caldicellulosiruptor saccharolyticus
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
Bifidobacterium longum
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
Bifidobacterium choerinum
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Thermus thermophilus
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Trichoderma viride
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Aspergillus sp.
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Bifidobacterium longum
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Lissachatina fulica
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Passalora fulva
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Pseudothermotoga thermarum
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Flavobacterium johnsoniae
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
Aspergillus niger
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
Pseudonocardia sp.
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
Rhizobium sp.
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
Microbacterium esteraromaticum
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
Mucilaginibacter sp. QM49
3.2.1.191
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Sphingomonas sp.
3.2.1.191
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Sphingopyxis alaskensis
3.2.1.191
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Aspergillus niger
3.2.1.191
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Fusarium sp.
3.2.1.191
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Terrabacter ginsenosidimutans
3.2.1.191
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Esteya vermicola
3.2.1.193
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Sulfolobus acidocaldarius
3.2.1.193
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Saccharolobus solfataricus
3.2.1.193
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Leuconostoc citreum
3.2.1.193
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Pseudarthrobacter chlorophenolicus
3.2.1.193
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Microbacterium esteraromaticum
3.2.1.194
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Pyrococcus furiosus
3.2.1.194
evolution
the enzyme belongs to the glycosyl hydrolase family 39, GH39
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Aspergillus niger
3.2.1.194
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Aspergillus sp.
3.2.1.194
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Sanguibacter keddieii
3.2.1.194
evolution
the enzyme belongs to the glycosyl hydrolase family 78, GH78
Absidia sp. (in: Fungi)
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1
Aspergillus niger
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1
Pyrococcus furiosus
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2
Pyrococcus furiosus
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2
Absidia sp. (in: Fungi)
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
Pyrococcus furiosus
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
Penicillium decumbens
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
Fusarium subglutinans
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
Penicillium sclerotiorum
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
Sanguibacter keddieii
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-ii enzymes convert ginsenosides Rg1 and Rh1, containing only the inner glucose without the outer sugar at C-6, are converted to ginsenosides F1 and aglycone protopanaxatriol (APPT), respectively, by hydrolyzing the inner glucose linked to C-6 but not the glucose linked to C-20 in the PPT-type ginsenosides with the hydrolysis pattern of F. Ginsenosidase type IV-ii enzymes also hydrolyze the outer glucose of ginsenoside Rf, which has the outer and inner glucose at C-6 with the hydrolysis pattern of E-1; the outer rhamnose of ginsenosides Re and Rg2, which have the outer rhamnose and inner glucose at C-6 with the hydrolysis attern of E-2, and the outer xylose of notoginsenosides R1 and R2, which contain the outer xylose and inner glucose at C-6 with the hydrolysis pattern of E-3
Aspergillus sp.
General Information (protein specific)
EC Number
General Information
Commentary
Organism
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Thermus thermophilus
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Pseudothermotoga thermarum
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 2, GH2
Microbacterium esteraromaticum
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Pseudonocardia sp.
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Microbacterium esteraromaticum
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Bifidobacterium longum
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Flavobacterium johnsoniae
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Mucilaginibacter sp. QM49
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 42, GH42
Caldicellulosiruptor saccharolyticus
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 51, GH51
Caldicellulosiruptor saccharolyticus
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 51, GH51
Bifidobacterium longum
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 51, GH51
Leuconostoc sp.
3.2.1.B23
evolution
the enzyme belongs to the glycosyl hydrolase family 51, GH51
Rhodanobacter ginsenosidimutans
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
Trichoderma viride
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
Caldicellulosiruptor saccharolyticus
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
Bifidobacterium longum
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
Panax ginseng
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
Leuconostoc sp.
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
Rhodanobacter ginsenosidimutans
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
Bifidobacterium breve
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
Trichoderma viride
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
Caldicellulosiruptor saccharolyticus
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
Bifidobacterium longum
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
Bifidobacterium choerinum
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Thermus thermophilus
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Trichoderma viride
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Aspergillus sp.
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Bifidobacterium longum
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Lissachatina fulica
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Passalora fulva
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Pseudothermotoga thermarum
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
Flavobacterium johnsoniae
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
Aspergillus niger
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
Pseudonocardia sp.
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
Rhizobium sp.
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
Microbacterium esteraromaticum
3.2.1.B23
physiological function
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
Mucilaginibacter sp. QM49
3.2.1.191
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Sphingomonas sp.
3.2.1.191
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Sphingopyxis alaskensis
3.2.1.191
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Aspergillus niger
3.2.1.191
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Fusarium sp.
3.2.1.191
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Terrabacter ginsenosidimutans
3.2.1.191
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Esteya vermicola
3.2.1.193
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Sulfolobus acidocaldarius
3.2.1.193
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Saccharolobus solfataricus
3.2.1.193
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Leuconostoc citreum
3.2.1.193
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Pseudarthrobacter chlorophenolicus
3.2.1.193
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Microbacterium esteraromaticum
3.2.1.194
evolution
the enzyme belongs to the glycosyl hydrolase family 1, GH1
Pyrococcus furiosus
3.2.1.194
evolution
the enzyme belongs to the glycosyl hydrolase family 39, GH39
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Aspergillus niger
3.2.1.194
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Aspergillus sp.
3.2.1.194
evolution
the enzyme belongs to the glycosyl hydrolase family 3, GH3
Sanguibacter keddieii
3.2.1.194
evolution
the enzyme belongs to the glycosyl hydrolase family 78, GH78
Absidia sp. (in: Fungi)
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1
Aspergillus niger
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-1 enzymes convert ginsenoside Rf to Rh1 by the hydrolysis of only the outer glucose linked to C-20 and not the inner glucose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-1
Pyrococcus furiosus
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2
Pyrococcus furiosus
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-2 enzymes convert ginsenosides Re and Rg2 to ginsenosides Rg1 and Rh1, respectively, by hydrolyzing only the outer rhamnose linked to C-6 in the PPT-type ginsenosides with the hydrolysis pattern of E-2
Absidia sp. (in: Fungi)
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
Pyrococcus furiosus
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
Thermoanaerobacterium thermosaccharolyticum
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
Penicillium decumbens
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
Fusarium subglutinans
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
Penicillium sclerotiorum
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-i-3 enzymes convert notoginsenosides R1 and R2 to ginsenosides Rg1 and Rh1, respectively, with the hydrolysis pattern of E-3 through the hydrolysis of the outer xylose linked to C-6 without further hydrolysis in the PPT-type ginsenosides
Sanguibacter keddieii
3.2.1.194
physiological function
ginsenosidase type IV hydrolyzes the sugars linked to C-6 in the PPT-type ginsenosides. Ginsenosidase type IV enzymes are subdivided into types IV-i-1, IV-i-2, IV-i-3, and IV-ii. Ginsenosidase type IV-ii enzymes convert ginsenosides Rg1 and Rh1, containing only the inner glucose without the outer sugar at C-6, are converted to ginsenosides F1 and aglycone protopanaxatriol (APPT), respectively, by hydrolyzing the inner glucose linked to C-6 but not the glucose linked to C-20 in the PPT-type ginsenosides with the hydrolysis pattern of F. Ginsenosidase type IV-ii enzymes also hydrolyze the outer glucose of ginsenoside Rf, which has the outer and inner glucose at C-6 with the hydrolysis pattern of E-1; the outer rhamnose of ginsenosides Re and Rg2, which have the outer rhamnose and inner glucose at C-6 with the hydrolysis attern of E-2, and the outer xylose of notoginsenosides R1 and R2, which contain the outer xylose and inner glucose at C-6 with the hydrolysis pattern of E-3
Aspergillus sp.