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Literature summary extracted from

  • Mugita, N.; Nambu, T.; Takahashi, K.; Wang, P.L.; Komasa, Y.
    Proteases, actinidin, papain and trypsin reduce oral biofilm on the tongue in elderly subjects and in vitro (2017), Arch. Oral Biol., 82, 233-240 .
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.21.4 medicine dental plaque is a causative factor for oral disease and a potential reservoir for respiratory infection in the elderly. Therefore, there is a critical need for the development of effective methods to remove oral biofilm. Proteases reduce oral biofilm in vivo in elderly subjects. Tablets containing actinidin remove tongue coating in elderly subjects. Oral Actinomyces biofilm is significantly reduced by the proteases papain, actinidin and trypsin. Papain and trypsin effectively digest the major fimbrial proteins, FimP and FimA, from Actinomyces. Actinidin, papain and trypsin reduce multispecies biofilm that is reconstructed in vitro. Papain and trypsin inhibit formation of multispecies biofilm in vitro Sus scrofa
3.4.22.2 medicine dental plaque is a causative factor for oral disease and a potential reservoir for respiratory infection in the elderly. Therefore, there is a critical need for the development of effective methods to remove oral biofilm. Proteases reduce oral biofilm in vivo in elderly subjects. Tablets containing actinidin remove tongue coating in elderly subjects. Oral Actinomyces biofilm is significantly reduced by the proteases papain, actinidin and trypsin. Papain and trypsin effectively digest the major fimbrial proteins, FimP and FimA, from Actinomyces. Actinidin, papain and trypsin reduce multispecies biofilm that is reconstructed in vitro. Papain and trypsin inhibit formation of multispecies biofilm in vitro Carica papaya
3.4.22.14 medicine dental plaque is a causative factor for oral disease and a potential reservoir for respiratory infection in the elderly. Therefore, there is a critical need for the development of effective methods to remove oral biofilm. Proteases reduce oral biofilm in vivo in elderly subjects. Tablets containing actinidin remove tongue coating in elderly subjects. Oral Actinomyces biofilm is significantly reduced by the proteases papain, actinidin and trypsin. Papain and trypsin effectively digest the major fimbrial proteins, FimP and FimA, from Actinomyces. Actinidin, papain and trypsin reduce multispecies biofilm that is reconstructed in vitro. Papain and trypsin inhibit formation of multispecies biofilm in vitro Actinidia chinensis

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.4 Sus scrofa P00761
-
-
3.4.22.2 Carica papaya P00784
-
-
3.4.22.14 Actinidia chinensis P00785
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.4 pancreas
-
 Sus scrofa
-

Synonyms

EC Number Synonyms Comment Organism
3.4.22.14 actinidin
-
 Actinidia chinensis