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Literature summary extracted from

  • Lopez, T.; Dalton, K.; Frydman, J.
    The mechanism and function of group II chaperonins (2015), J. Mol. Biol., 427, 2919-2930 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.7 ATP + H2O + a folded polypeptide Methanococcus maripaludis
-
ADP + phosphate + an unfolded polypeptide
-
?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.7 Methanococcus maripaludis Q877G8
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.7 ATP + H2O + a folded polypeptide
-
Methanococcus maripaludis ADP + phosphate + an unfolded polypeptide
-
?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.7 CCT
-
Methanococcus maripaludis
5.6.1.7 chaperonin
-
Methanococcus maripaludis
5.6.1.7 CPN
-
Methanococcus maripaludis
5.6.1.7 TriC
-
Methanococcus maripaludis

General Information

EC Number General Information Comment Organism
5.6.1.7 physiological function the enzyme is absolutely required for folding many essential proteins, including cytoskeletal proteins such as tubulin and actin, as well as cell cycle regulators such as CDC20 and CDH1 Methanococcus maripaludis