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Literature summary extracted from

  • Zargari, M.; Sharafeddin, F.; Mahrooz, A.; Alizadeh, A.; Masoumi, P.
    The common variant Q192R at the paraoxonase 1 (PON1) gene and its activity are responsible for a portion of the altered antioxidant status in type 2 diabetes (2016), Exp. Biol. Med., 241, 1489-1496 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
3.1.1.2 Q192R the mutation is related to vascular disease and variation in the enzyme activity Homo sapiens
3.1.8.1 Q192R the mutation is related to vascular disease and variation in the enzyme activity Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.2 Ca2+ 1 mM used in assay conditions Homo sapiens
3.1.8.1 Ca2+ 2 mM used in assay conditions Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.2 Homo sapiens
-
-
-
3.1.8.1 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.2 phenyl acetate + H2O
-
 Homo sapiens phenol + acetate
-
 ?
3.1.8.1 paraoxon + H2O
-
 Homo sapiens 4-nitrophenol + diethyl phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.2 PON-aryl
-
 Homo sapiens
3.1.8.1 PON-para
-
 Homo sapiens