Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • El Hiani, Y.; Negoda, A.; Linsdell, P.
    Cytoplasmic pathway followed by chloride ions to enter the CFTR channel pore (2016), Cell. Mol. Life Sci., 73, 1917-1925 .
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
5.6.1.6 A196C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
5.6.1.6 A252C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
5.6.1.6 A367C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
5.6.1.6 G194C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
5.6.1.6 G241C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
5.6.1.6 L188C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
5.6.1.6 L197C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
5.6.1.6 M244C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
5.6.1.6 M245C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
5.6.1.6 N186C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
5.6.1.6 N189C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
5.6.1.6 N306C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
5.6.1.6 S307C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
5.6.1.6 W356C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.6.1.6 plasma membrane
-
 Homo sapiens 5886
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.6 ATP + H2O + closed Cl- channel Homo sapiens
-
 ADP + phosphate + open Cl- channel
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.6 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.6 ATP + H2O + closed Cl- channel
-
 Homo sapiens ADP + phosphate + open Cl- channel
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.6 CFTR
-
 Homo sapiens
5.6.1.6 cystic fibrosis transmembrane conductance regulator
-
 Homo sapiens