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Literature summary extracted from

  • Yu, H.; Lai, H.J.; Lin, T.W.; Chen, C.S.; Lo, S.J.
    Loss of DNase II function in the gonad is associated with a higher expression of antimicrobial genes in Caenorhabditis elegans (2015), Biochem. J., 470, 145-154 .
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
3.1.22.1 Caenorhabditis elegans P34387
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3.1.22.1 Caenorhabditis elegans Q17778
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Source Tissue

EC Number Source Tissue Comment Organism Textmining

Synonyms

EC Number Synonyms Comment Organism
3.1.22.1 crn-7
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Caenorhabditis elegans
3.1.22.1 Nuc-1
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Caenorhabditis elegans

General Information

EC Number General Information Comment Organism
3.1.22.1 malfunction loss of CRN-7 leads to up-regulation of antimicrobial genes Caenorhabditis elegans
3.1.22.1 malfunction loss of NUC-1 leads to up-regulation of antimicrobial genes Caenorhabditis elegans
3.1.22.1 physiological function the enzyme plays a role in degrading apoptotic DNA in distinct sites of the gonad, and acts as negative regulators of innate immunity Caenorhabditis elegans