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Literature summary extracted from

  • Grell, T.A.J.; Bell, B.N.; Nguyen, C.; Dowling, D.P.; Bruender, N.A.; Bandarian, V.; Drennan, C.L.
    Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity (2018), Protein Sci., 28, 202-215 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.3.99.3 expression in Escherichia coli Escherichia coli

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
4.3.99.3 the crystal structure of the enzyme is determined to 2.1 A resolution by multi-wavelength anomalous dispersion Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.3.99.3 6-carboxy-5,6,7,8-tetrahydropterin Escherichia coli
-
7-carboxy-7-carbaguanine + NH3
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.3.99.3 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.99.3 6-carboxy-5,6,7,8-tetrahydropterin
-
Escherichia coli 7-carboxy-7-carbaguanine + NH3
-
?

Synonyms

EC Number Synonyms Comment Organism
4.3.99.3 queE
-
Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
4.3.99.3 S-adenosyl-L-methionine S-adenosyl-L-methionine-dependent radical enzyme Escherichia coli