Literature summary extracted from

Kaplan, A.; Gaschler, M.M.; Dunn, D.E.; Colligan, R.; Brown, L.M.; Palmer, A.G.; Lo, D.C.; Stockwell, B.R.
Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective (2015), Proc. Natl. Acad. Sci. USA, 112, E2245-E2252 .

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
5.3.4.1	16F16	irreversible inhibition	Rattus norvegicus
5.3.4.1	2-[[4-(cyclopropanecarbonyl)piperazin-1-yl]methyl]-1,2-benzothiazol-3(2H)-one	potent, reversible inhibition	Rattus norvegicus
5.3.4.1	4-(6-methylimidazo[1,2-a]pyridin-2-yl)benzene-1,2-diol	-	Rattus norvegicus
5.3.4.1	N-[2-methyl-2-(morpholin-4-yl)propyl]-1,2-benzothiazol-3-amine	-	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.3.4.1	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
5.3.4.1	PC-12 cell	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5.3.4.1	insulin	-	Rattus norvegicus	reduced insulin	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
5.3.4.1	PDI	-	Rattus norvegicus
5.3.4.1	protein disulfide isomerase	-	Rattus norvegicus

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Release 2023.1 (January 2023)