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Literature summary extracted from

  • Zebelo, S.; Song, Y.; Kloepper, J.W.; Fadamiro, H.
    Rhizobacteria activates (+)-delta-cadinene synthase genes and induces systemic resistance in cotton against beet armyworm (Spodoptera exigua) (2016), Plant Cell Environ., 39, 935-943 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.3.13 gene Cdn1-C1, real-time PCR expression analysis Gossypium hirsutum

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
4.2.3.13 crystal structure analysis, PDB ID 3G4F Gossypium hirsutum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.3.13 (2E,6E)-farnesyl diphosphate Gossypium hirsutum
-
(+)-delta-cadinene + diphosphate
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.13 Gossypium hirsutum
-
cultivar Max-9
-
4.2.3.13 Gossypium hirsutum P93665 var. Max-9
-
4.2.3.13 Gossypium hirsutum Q39760 var. Max-9
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.3.13 leaf
-
Gossypium hirsutum
-
4.2.3.13 additional information isozyme real-time PCR expression analysis in leaves of cotton from various plant treatments Gossypium hirsutum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.13 (2E,6E)-farnesyl diphosphate
-
Gossypium hirsutum (+)-delta-cadinene + diphosphate
-
?

Synonyms

EC Number Synonyms Comment Organism
4.2.3.13 CAD
-
Gossypium hirsutum
4.2.3.13 CDN1
-
Gossypium hirsutum
4.2.3.13 Cdn1-C1
-
Gossypium hirsutum
4.2.3.13 Cdn1-C14
-
Gossypium hirsutum
4.2.3.13 delta-cadinene synthase
-
Gossypium hirsutum

Expression

EC Number Organism Comment Expression
4.2.3.13 Gossypium hirsutum jasmonic acid induces the enzyme. Plant growth-promoting rhizobacteria (PGPR) treatment induces increased level of gossypol in cotton PGPR-treated plants. Cotton pathogen Spodoptera exigua shows reduced larval feeding and development on PGPR-treated plants up
4.2.3.13 Gossypium hirsutum Rhizobacteria (Bacillus spp.) increase (+)-delta-cadinene synthase gene expression 2fold as compared to the control up

General Information

EC Number General Information Comment Organism
4.2.3.13 evolution the CAD is encoded by a gene family, which is divided into two subfamilies CAD1-A and CAD1-C (Cdn1-C1, Cdn1-C14, Cdn1-A and Cdn1-C3), based on sequence similarities. The diploid genome of Gossypium arboreum contains about six members of CAD1- C and a single copy of CAD1-A Gossypium hirsutum
4.2.3.13 physiological function in cotton, (+)-delta-cadinene synthase (CAD) catalyses the cyclization of farnesyl diphosphate to (+)-delta-cadinene via a nerolidyl diphosphate intermediate and is the first step in the biosynthesis of gossypol and its precursor terpene aldehyde Gossypium hirsutum
4.2.3.13 physiological function in cotton, (+)-delta-cadinene synthase (CAD) catalyses the cyclization of farnesyl diphosphate to (+)-delta-cadinene via a nerolidyl diphosphate intermediate and is the first step in the biosynthesis of gossypol and its precursor terpene aldehyde. Increased enzyme expression due to jasmonic acid treatment or plant growth-promoting rhizobacteria (PGPR) treatment leads to increased levels of gossypol in plants. Cotton pathogen Spodoptera exigua shows reduced larval feeding and development on PGPR-treated plants Gossypium hirsutum
4.2.3.13 physiological function the enzyme distributes to systemic resistance in cotton against beet armyworm Spodoptera exigua Gossypium hirsutum