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Literature summary extracted from

  • Kaur, G.; Subramanian, S.
    Evolutionary analysis of a novel zinc ribbon in the N-terminal region of threonine synthase (2017), Cell Cycle, 16, 1918-1926 .
    View publication on PubMedView publication on EuropePMC

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.2.3.1 Zn2+ contains a zinc ribbon domain Mycobacterium tuberculosis
4.2.3.1 Zn2+ contains a zinc ribbon domain Arabidopsis thaliana
4.2.3.1 Zn2+ contains a zinc ribbon domain Escherichia coli
4.2.3.1 Zn2+ contains a zinc ribbon domain Aquifex aeolicus
4.2.3.1 Zn2+ contains a zinc ribbon domain Burkholderia thailandensis
4.2.3.1 Zn2+ contains a zinc ribbon domain Saccharomyces cerevisiae
4.2.3.1 Zn2+ contains a zinc ribbon domain Brucella melitensis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.3.1 O-phospho-L-homoserine + H2O Mycobacterium tuberculosis
-
 L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O Thermus thermophilus
-
 L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O Arabidopsis thaliana
-
 L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O Escherichia coli
-
 L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O Aquifex aeolicus
-
 L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O Burkholderia thailandensis
-
 L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O Saccharomyces cerevisiae
-
 L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O Brucella melitensis
-
 L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O Brucella melitensis 16M
-
 L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O Burkholderia thailandensis ATCC 700388
-
 L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O Mycobacterium tuberculosis H37Rv
-
 L-threonine + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.1 Aquifex aeolicus O66740
-
-
4.2.3.1 Arabidopsis thaliana Q9S7B5
-
-
4.2.3.1 Brucella melitensis Q8YFS0 biotype 1
-
4.2.3.1 Brucella melitensis 16M Q8YFS0 biotype 1
-
4.2.3.1 Burkholderia thailandensis Q2SWH9
-
-
4.2.3.1 Burkholderia thailandensis ATCC 700388 Q2SWH9
-
-
4.2.3.1 Escherichia coli P00934
-
-
4.2.3.1 Mycobacterium tuberculosis P9WG59
-
-
4.2.3.1 Mycobacterium tuberculosis H37Rv P9WG59
-
-
4.2.3.1 Saccharomyces cerevisiae P16120
-
-
4.2.3.1 Thermus thermophilus P83823
-
-
4.2.3.1 Thermus thermophilus Q5SL02
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.1 O-phospho-L-homoserine + H2O
-
 Mycobacterium tuberculosis L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O
-
 Thermus thermophilus L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O
-
 Arabidopsis thaliana L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O
-
 Escherichia coli L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O
-
 Aquifex aeolicus L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O
-
 Burkholderia thailandensis L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O
-
 Saccharomyces cerevisiae L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O
-
 Brucella melitensis L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O
-
 Brucella melitensis 16M L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O
-
 Burkholderia thailandensis ATCC 700388 L-threonine + phosphate
-
 ?
4.2.3.1 O-phospho-L-homoserine + H2O
-
 Mycobacterium tuberculosis H37Rv L-threonine + phosphate
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
4.2.3.1 pyridoxal 5'-phosphate
-
 Mycobacterium tuberculosis
4.2.3.1 pyridoxal 5'-phosphate
-
 Thermus thermophilus
4.2.3.1 pyridoxal 5'-phosphate
-
 Arabidopsis thaliana
4.2.3.1 pyridoxal 5'-phosphate
-
 Escherichia coli
4.2.3.1 pyridoxal 5'-phosphate
-
 Aquifex aeolicus
4.2.3.1 pyridoxal 5'-phosphate
-
 Burkholderia thailandensis
4.2.3.1 pyridoxal 5'-phosphate
-
 Saccharomyces cerevisiae
4.2.3.1 pyridoxal 5'-phosphate
-
 Brucella melitensis