Any feedback?
Literature summary extracted from
- ATP binding enables substrate release from multidrug resistance protein 1 (2018), Cell, 172, 81-89 .
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.6.2.2 | leukotriene C4 | - |
Bos taurus |  |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 7.6.2.2 | expressed in Sf9 insect cells | Bos taurus |
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 7.6.2.2 | E1454Q | inactive | Bos taurus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.6.2.2 | ATP + H2O + xenobiotic[side 1] | Bos taurus | - |
ADP + phosphate + xenobiotic[side 2] | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.6.2.2 | Bos taurus | Q8HXQ5 | - |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 7.6.2.2 | Sepharose 4 column chromatography and Superose 6 gel filtration | Bos taurus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.6.2.2 | ATP + H2O + xenobiotic[side 1] | - |
Bos taurus | ADP + phosphate + xenobiotic[side 2] | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 7.6.2.2 | MRP1 | - |
Bos taurus |
| 7.6.2.2 | multidrug resistance protein 1 | - |
Bos taurus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
