EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.5.1.2 | (2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl dihydrogen phosphate | - |
Escherichia coli | |
6.5.1.2 | (2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl dihydrogen phosphate | - |
Haemophilus influenzae | |
6.5.1.2 | (2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl dihydrogen phosphate | - |
Mycobacterium tuberculosis | |
6.5.1.2 | (2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl dihydrogen phosphate | - |
Mycoplasma pneumoniae | |
6.5.1.2 | (2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl dihydrogen phosphate | - |
Staphylococcus aureus | |
6.5.1.2 | (2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl dihydrogen phosphate | - |
Streptococcus pneumoniae | |
6.5.1.2 | (3aR,5R,6R,6aS)-5-[6-amino-2-(methylsulfanyl)-9H-purin-9-yl]-6-hydroxy-2-sulfanyltetrahydro-2H-2lambda-5-furo[2,3-d][1,3,2]dioxaphosphol-2-one | - |
Escherichia coli | |
6.5.1.2 | (3aR,5R,6R,6aS)-5-[6-amino-2-(methylsulfanyl)-9H-purin-9-yl]-6-hydroxy-2-sulfanyltetrahydro-2H-2lambda-5-furo[2,3-d][1,3,2]dioxaphosphol-2-one | - |
Mycobacterium tuberculosis | |
6.5.1.2 | (3aR,5R,6R,6aS)-5-[6-amino-2-(methylsulfanyl)-9H-purin-9-yl]-6-hydroxy-2-sulfanyltetrahydro-2H-2lambda-5-furo[2,3-d][1,3,2]dioxaphosphol-2-one | - |
Mycoplasma pneumoniae | |
6.5.1.2 | (3aR,5R,6R,6aS)-5-[6-amino-2-(methylsulfanyl)-9H-purin-9-yl]-6-hydroxy-2-sulfanyltetrahydro-2H-2lambda-5-furo[2,3-d][1,3,2]dioxaphosphol-2-one | - |
Staphylococcus aureus | |
6.5.1.2 | (3aR,5R,6R,6aS)-5-[6-amino-2-(methylsulfanyl)-9H-purin-9-yl]-6-hydroxy-2-sulfanyltetrahydro-2H-2lambda-5-furo[2,3-d][1,3,2]dioxaphosphol-2-one | - |
Streptococcus pneumoniae | |
6.5.1.2 | (3aR,5R,6R,6aS)-5-[6-amino-2-(methylsulfanyl)-9H-purin-9-yl]-6-hydroxy-2-sulfanyltetrahydro-2H-2lambda5-furo[2,3-d][1,3,2]dioxaphosphol-2-one | - |
Haemophilus influenzae | |
6.5.1.2 | 2-(butylsulfanyl)-5'-deoxyadenosine | - |
Escherichia coli | |
6.5.1.2 | 2-(butylsulfanyl)-5'-deoxyadenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 2-(butylsulfanyl)-5'-deoxyadenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 2-(butylsulfanyl)-5'-deoxyadenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 2-(butylsulfanyl)-5'-deoxyadenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 2-(butylsulfanyl)adenosine | - |
Escherichia coli | |
6.5.1.2 | 2-(butylsulfanyl)adenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 2-(butylsulfanyl)adenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 2-(butylsulfanyl)adenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 2-(butylsulfanyl)adenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 2-(cyclobutylmethoxy)-5'-deoxy-5'-fluoroadenosine | - |
Escherichia coli | |
6.5.1.2 | 2-(cyclobutylmethoxy)-5'-deoxy-5'-fluoroadenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 2-(cyclobutylmethoxy)-5'-deoxy-5'-fluoroadenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 2-(cyclobutylmethoxy)-5'-deoxy-5'-fluoroadenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 2-(cyclobutylmethoxy)-5'-deoxy-5'-fluoroadenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 2-(cyclopentyloxy)-3',5'-dideoxy-3'-[(3,5-dichlorophenyl)methyl]adenosine | - |
Escherichia coli | |
6.5.1.2 | 2-(cyclopentyloxy)-3',5'-dideoxy-3'-[(3,5-dichlorophenyl)methyl]adenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 2-(cyclopentyloxy)-3',5'-dideoxy-3'-[(3,5-dichlorophenyl)methyl]adenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 2-(cyclopentyloxy)-3',5'-dideoxy-3'-[(3,5-dichlorophenyl)methyl]adenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 2-(cyclopentyloxy)-3',5'-dideoxy-3'-[(3,5-dichlorophenyl)methyl]adenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 2-(cyclopentyloxy)-3',5'-dideoxy-5'-fluoro-3'-(1H-triaziren-1-yl)adenosine | - |
Escherichia coli | |
6.5.1.2 | 2-(cyclopentyloxy)-3',5'-dideoxy-5'-fluoro-3'-(1H-triaziren-1-yl)adenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 2-(cyclopentyloxy)-3',5'-dideoxy-5'-fluoro-3'-(1H-triaziren-1-yl)adenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 2-(cyclopentyloxy)-3',5'-dideoxy-5'-fluoro-3'-(1H-triaziren-1-yl)adenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 2-(cyclopentyloxy)-3',5'-dideoxy-5'-fluoro-3'-(1H-triaziren-1-yl)adenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 2-(cyclopentyloxy)-5'-deoxy-5'-fluoroadenosine | - |
Escherichia coli | |
6.5.1.2 | 2-(cyclopentyloxy)-5'-deoxy-5'-fluoroadenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 2-(cyclopentyloxy)-5'-deoxy-5'-fluoroadenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 2-(cyclopentyloxy)-5'-deoxy-5'-fluoroadenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 2-(cyclopentyloxy)-5'-deoxy-5'-fluoroadenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 2-(cyclopentyloxy)-5'-deoxyadenosine | - |
Escherichia coli | |
6.5.1.2 | 2-(cyclopentyloxy)-5'-deoxyadenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 2-(cyclopentyloxy)-5'-deoxyadenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 2-(cyclopentyloxy)-5'-deoxyadenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 2-(cyclopentyloxy)-5'-deoxyadenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 2-(cyclopentyloxy)adenosine | - |
Escherichia coli | |
6.5.1.2 | 2-(cyclopentyloxy)adenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 2-(cyclopentyloxy)adenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 2-(cyclopentyloxy)adenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 2-(cyclopentyloxy)adenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 2-(cyclopentylsulfanyl)adenosine | - |
Escherichia coli | |
6.5.1.2 | 2-(cyclopentylsulfanyl)adenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 2-(cyclopentylsulfanyl)adenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 2-(cyclopentylsulfanyl)adenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 2-(cyclopentylsulfanyl)adenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 2-[(bicyclo[3.1.0]hexan-3-yl)oxy]-5'-deoxyadenosine | - |
Escherichia coli | |
6.5.1.2 | 2-[(bicyclo[3.1.0]hexan-3-yl)oxy]-5'-deoxyadenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 2-[(bicyclo[3.1.0]hexan-3-yl)oxy]-5'-deoxyadenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 2-[(bicyclo[3.1.0]hexan-3-yl)oxy]-5'-deoxyadenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 2-[(bicyclo[3.1.0]hexan-3-yl)oxy]-5'-deoxyadenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 2-[(decahydronaphthalen-2-yl)oxy]-5'-deoxyadenosine | - |
Escherichia coli | |
6.5.1.2 | 2-[(decahydronaphthalen-2-yl)oxy]-5'-deoxyadenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 2-[(decahydronaphthalen-2-yl)oxy]-5'-deoxyadenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 2-[(decahydronaphthalen-2-yl)oxy]-5'-deoxyadenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 2-[(decahydronaphthalen-2-yl)oxy]-5'-deoxyadenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 2-[(decahydronaphthalen-2-yl)oxy]adenosine | - |
Escherichia coli | |
6.5.1.2 | 2-[(decahydronaphthalen-2-yl)oxy]adenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 2-[(decahydronaphthalen-2-yl)oxy]adenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 2-[(decahydronaphthalen-2-yl)oxy]adenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 2-[(decahydronaphthalen-2-yl)oxy]adenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 3'-chloro-2-(cyclopentyloxy)-3',5'-dideoxyadenosine | - |
Escherichia coli | |
6.5.1.2 | 3'-chloro-2-(cyclopentyloxy)-3',5'-dideoxyadenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 3'-chloro-2-(cyclopentyloxy)-3',5'-dideoxyadenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 3'-chloro-2-(cyclopentyloxy)-3',5'-dideoxyadenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 3'-chloro-2-(cyclopentyloxy)-3',5'-dideoxyadenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 3'-chloro-2-(cyclopentyloxy)-3'-deoxyadenosine | - |
Escherichia coli | |
6.5.1.2 | 3'-chloro-2-(cyclopentyloxy)-3'-deoxyadenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 3'-chloro-2-(cyclopentyloxy)-3'-deoxyadenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 3'-chloro-2-(cyclopentyloxy)-3'-deoxyadenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 3'-chloro-2-(cyclopentyloxy)-3'-deoxyadenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 3'-chloro-3',5'-dideoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | - |
Escherichia coli | |
6.5.1.2 | 3'-chloro-3',5'-dideoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 3'-chloro-3',5'-dideoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 3'-chloro-3',5'-dideoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 3'-chloro-3',5'-dideoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | - |
Escherichia coli | |
6.5.1.2 | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | - |
Haemophilus influenzae | |
6.5.1.2 | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | - |
Mycobacterium tuberculosis | |
6.5.1.2 | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | - |
Staphylococcus aureus | |
6.5.1.2 | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | - |
Streptococcus pneumoniae | |
6.5.1.2 | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | - |
Escherichia coli | |
6.5.1.2 | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | - |
Haemophilus influenzae | |
6.5.1.2 | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | - |
Mycobacterium tuberculosis | |
6.5.1.2 | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | - |
Staphylococcus aureus | |
6.5.1.2 | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | - |
Streptococcus pneumoniae | |
6.5.1.2 | 5'-deoxy-2-phenoxyadenosine | - |
Escherichia coli | |
6.5.1.2 | 5'-deoxy-2-phenoxyadenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 5'-deoxy-2-phenoxyadenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 5'-deoxy-2-phenoxyadenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 5'-deoxy-2-phenoxyadenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 5'-deoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | - |
Escherichia coli | |
6.5.1.2 | 5'-deoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 5'-deoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 5'-deoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 5'-deoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 5'-deoxy-2-[(trans-4-methylcyclohexyl)oxy]adenosine | - |
Escherichia coli | |
6.5.1.2 | 5'-deoxy-2-[(trans-4-methylcyclohexyl)oxy]adenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 5'-deoxy-2-[(trans-4-methylcyclohexyl)oxy]adenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 5'-deoxy-2-[(trans-4-methylcyclohexyl)oxy]adenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 5'-deoxy-2-[(trans-4-methylcyclohexyl)oxy]adenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 5'-deoxy-2-[(tricyclo[3.3.1.1~3,7~]decan-2-yl)methoxy]adenosine | - |
Escherichia coli | |
6.5.1.2 | 5'-deoxy-2-[(tricyclo[3.3.1.1~3,7~]decan-2-yl)methoxy]adenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 5'-deoxy-2-[(tricyclo[3.3.1.1~3,7~]decan-2-yl)methoxy]adenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 5'-deoxy-2-[(tricyclo[3.3.1.1~3,7~]decan-2-yl)methoxy]adenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 5'-deoxy-2-[(tricyclo[3.3.1.1~3,7~]decan-2-yl)methoxy]adenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 5'-deoxy-5'-fluoro-2-[(1,3-thiazol-2-yl)methoxy]adenosine | - |
Escherichia coli | |
6.5.1.2 | 5'-deoxy-5'-fluoro-2-[(1,3-thiazol-2-yl)methoxy]adenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 5'-deoxy-5'-fluoro-2-[(1,3-thiazol-2-yl)methoxy]adenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 5'-deoxy-5'-fluoro-2-[(1,3-thiazol-2-yl)methoxy]adenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 5'-deoxy-5'-fluoro-2-[(1,3-thiazol-2-yl)methoxy]adenosine | - |
Streptococcus pneumoniae | |
6.5.1.2 | 5'-deoxy-5'-fluoro-2-[[1-(hydroxymethyl)cyclopropyl]methoxy]adenosine | - |
Escherichia coli | |
6.5.1.2 | 5'-deoxy-5'-fluoro-2-[[1-(hydroxymethyl)cyclopropyl]methoxy]adenosine | - |
Haemophilus influenzae | |
6.5.1.2 | 5'-deoxy-5'-fluoro-2-[[1-(hydroxymethyl)cyclopropyl]methoxy]adenosine | - |
Mycoplasma pneumoniae | |
6.5.1.2 | 5'-deoxy-5'-fluoro-2-[[1-(hydroxymethyl)cyclopropyl]methoxy]adenosine | - |
Staphylococcus aureus | |
6.5.1.2 | 5'-deoxy-5'-fluoro-2-[[1-(hydroxymethyl)cyclopropyl]methoxy]adenosine | - |
Streptococcus pneumoniae |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.5.1.2 | NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | Staphylococcus aureus | - |
(deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
6.5.1.2 | NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | Haemophilus influenzae | - |
(deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
6.5.1.2 | NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | Escherichia coli | - |
(deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
6.5.1.2 | NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | Streptococcus pneumoniae | - |
(deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
6.5.1.2 | NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | Mycobacterium tuberculosis | - |
(deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
6.5.1.2 | NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | Mycoplasma pneumoniae | - |
(deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.5.1.2 | Escherichia coli | - |
- |
- |
6.5.1.2 | Haemophilus influenzae | - |
- |
- |
6.5.1.2 | Mycobacterium tuberculosis | - |
- |
- |
6.5.1.2 | Mycoplasma pneumoniae | - |
- |
- |
6.5.1.2 | Staphylococcus aureus | - |
- |
- |
6.5.1.2 | Streptococcus pneumoniae | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.5.1.2 | NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | - |
Staphylococcus aureus | (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
6.5.1.2 | NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | - |
Haemophilus influenzae | (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
6.5.1.2 | NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | - |
Escherichia coli | (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
6.5.1.2 | NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | - |
Streptococcus pneumoniae | (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
6.5.1.2 | NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | - |
Mycobacterium tuberculosis | (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
6.5.1.2 | NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | - |
Mycoplasma pneumoniae | (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.5.1.2 | beta-NAD+ -dependent DNA ligase | - |
Staphylococcus aureus |
6.5.1.2 | beta-NAD+ -dependent DNA ligase | - |
Haemophilus influenzae |
6.5.1.2 | beta-NAD+ -dependent DNA ligase | - |
Escherichia coli |
6.5.1.2 | beta-NAD+ -dependent DNA ligase | - |
Streptococcus pneumoniae |
6.5.1.2 | beta-NAD+ -dependent DNA ligase | - |
Mycobacterium tuberculosis |
6.5.1.2 | beta-NAD+-dependent DNA ligase | - |
Mycoplasma pneumoniae |
6.5.1.2 | LigA | - |
Staphylococcus aureus |
6.5.1.2 | LigA | - |
Haemophilus influenzae |
6.5.1.2 | LigA | - |
Escherichia coli |
6.5.1.2 | LigA | - |
Streptococcus pneumoniae |
6.5.1.2 | LigA | - |
Mycobacterium tuberculosis |
6.5.1.2 | LigA | - |
Mycoplasma pneumoniae |
6.5.1.2 | NAD+-dependent DNA ligase | - |
Staphylococcus aureus |
6.5.1.2 | NAD+-dependent DNA ligase | - |
Haemophilus influenzae |
6.5.1.2 | NAD+-dependent DNA ligase | - |
Escherichia coli |
6.5.1.2 | NAD+-dependent DNA ligase | - |
Streptococcus pneumoniae |
6.5.1.2 | NAD+-dependent DNA ligase | - |
Mycobacterium tuberculosis |
6.5.1.2 | NAD+-dependent DNA ligase | - |
Mycoplasma pneumoniae |
6.5.1.2 | NDL | - |
Staphylococcus aureus |
6.5.1.2 | NDL | - |
Haemophilus influenzae |
6.5.1.2 | NDL | - |
Escherichia coli |
6.5.1.2 | NDL | - |
Streptococcus pneumoniae |
6.5.1.2 | NDL | - |
Mycobacterium tuberculosis |
6.5.1.2 | NDL | - |
Mycoplasma pneumoniae |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
6.5.1.2 | NAD+ | - |
Staphylococcus aureus | |
6.5.1.2 | NAD+ | - |
Haemophilus influenzae | |
6.5.1.2 | NAD+ | - |
Escherichia coli | |
6.5.1.2 | NAD+ | - |
Streptococcus pneumoniae | |
6.5.1.2 | NAD+ | - |
Mycobacterium tuberculosis | |
6.5.1.2 | NAD+ | - |
Mycoplasma pneumoniae |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
6.5.1.2 | 0.00001 | - |
pH and temperature not specified in the publication | Mycoplasma pneumoniae | 5'-deoxy-2-[(trans-4-methylcyclohexyl)oxy]adenosine | |
6.5.1.2 | 0.00001 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 2-(cyclopentyloxy)-3',5'-dideoxy-3'-[(3,5-dichlorophenyl)methyl]adenosine | |
6.5.1.2 | 0.00002 | - |
pH and temperature not specified in the publication | Mycoplasma pneumoniae | 2-(cyclobutylmethoxy)-5'-deoxy-5'-fluoroadenosine | |
6.5.1.2 | 0.00002 | - |
pH and temperature not specified in the publication | Mycoplasma pneumoniae | 2-(cyclopentyloxy)-5'-deoxyadenosine | |
6.5.1.2 | 0.00002 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 3'-chloro-3',5'-dideoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | |
6.5.1.2 | 0.00003 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 3'-chloro-3',5'-dideoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | |
6.5.1.2 | 0.00004 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 2-[(decahydronaphthalen-2-yl)oxy]-5'-deoxyadenosine | |
6.5.1.2 | 0.00004 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 3'-chloro-2-(cyclopentyloxy)-3',5'-dideoxyadenosine | |
6.5.1.2 | 0.00004 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 3'-chloro-2-(cyclopentyloxy)-3',5'-dideoxyadenosine | |
6.5.1.2 | 0.00004 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 5'-deoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | |
6.5.1.2 | 0.00005 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 2-(cyclobutylmethoxy)-5'-deoxy-5'-fluoroadenosine | |
6.5.1.2 | 0.00005 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 5'-deoxy-2-[(trans-4-methylcyclohexyl)oxy]adenosine | |
6.5.1.2 | 0.00006 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 2-(cyclobutylmethoxy)-5'-deoxy-5'-fluoroadenosine | |
6.5.1.2 | 0.00006 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 2-[(bicyclo[3.1.0]hexan-3-yl)oxy]-5'-deoxyadenosine | |
6.5.1.2 | 0.00006 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 5'-deoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | |
6.5.1.2 | 0.00006 | - |
pH and temperature not specified in the publication | Mycoplasma pneumoniae | 5'-deoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | |
6.5.1.2 | 0.00007 | - |
pH and temperature not specified in the publication | Mycoplasma pneumoniae | 2-(butylsulfanyl)adenosine | |
6.5.1.2 | 0.00007 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 2-(cyclopentyloxy)-3',5'-dideoxy-5'-fluoro-3'-(1H-triaziren-1-yl)adenosine | |
6.5.1.2 | 0.00008 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 2-(butylsulfanyl)adenosine | |
6.5.1.2 | 0.00008 | - |
pH and temperature not specified in the publication | Haemophilus influenzae | 2-(cyclobutylmethoxy)-5'-deoxy-5'-fluoroadenosine | |
6.5.1.2 | 0.00008 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 2-(cyclopentyloxy)-5'-deoxyadenosine | |
6.5.1.2 | 0.00008 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 2-[(decahydronaphthalen-2-yl)oxy]adenosine | |
6.5.1.2 | 0.00008 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 3'-chloro-2-(cyclopentyloxy)-3'-deoxyadenosine | |
6.5.1.2 | 0.00008 | - |
pH and temperature not specified in the publication | Haemophilus influenzae | 5'-deoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | |
6.5.1.2 | 0.00009 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 2-(cyclopentyloxy)-3',5'-dideoxy-5'-fluoro-3'-(1H-triaziren-1-yl)adenosine | |
6.5.1.2 | 0.00011 | - |
pH and temperature not specified in the publication | Haemophilus influenzae | 2-(cyclopentyloxy)-5'-deoxyadenosine | |
6.5.1.2 | 0.00011 | - |
pH and temperature not specified in the publication | Haemophilus influenzae | 5'-deoxy-2-[(trans-4-methylcyclohexyl)oxy]adenosine | |
6.5.1.2 | 0.00011 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 3'-chloro-2-(cyclopentyloxy)-3'-deoxyadenosine | |
6.5.1.2 | 0.00012 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 2-(cyclopentyloxy)-5'-deoxyadenosine | |
6.5.1.2 | 0.00012 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 2-(cyclopentyloxy)-5'-deoxy-5'-fluoroadenosine | |
6.5.1.2 | 0.00012 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 2-(cyclopentyloxy)-5'-deoxy-5'-fluoroadenosine | |
6.5.1.2 | 0.00013 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 2-(butylsulfanyl)-5'-deoxyadenosine | |
6.5.1.2 | 0.00013 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 2-(cyclopentyloxy)-3',5'-dideoxy-3'-[(3,5-dichlorophenyl)methyl]adenosine | |
6.5.1.2 | 0.00013 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 2-[(bicyclo[3.1.0]hexan-3-yl)oxy]-5'-deoxyadenosine | |
6.5.1.2 | 0.00014 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 2-(butylsulfanyl)adenosine | |
6.5.1.2 | 0.00014 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 5'-deoxy-2-phenoxyadenosine | |
6.5.1.2 | 0.00015 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 2-(cyclopentyloxy)adenosine | |
6.5.1.2 | 0.00016 | - |
pH and temperature not specified in the publication | Escherichia coli | 2-(cyclobutylmethoxy)-5'-deoxy-5'-fluoroadenosine | |
6.5.1.2 | 0.00016 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 5'-deoxy-2-[(trans-4-methylcyclohexyl)oxy]adenosine | |
6.5.1.2 | 0.00017 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 2-(butylsulfanyl)-5'-deoxyadenosine | |
6.5.1.2 | 0.00018 | - |
pH and temperature not specified in the publication | Escherichia coli | 5'-deoxy-2-[(spiro[2.2]pentan-1-yl)methoxy]adenosine | |
6.5.1.2 | 0.0002 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 5'-deoxy-2-[(tricyclo[3.3.1.1~3,7~]decan-2-yl)methoxy]adenosine | |
6.5.1.2 | 0.00026 | - |
pH and temperature not specified in the publication | Haemophilus influenzae | 2-[(decahydronaphthalen-2-yl)oxy]-5'-deoxyadenosine | |
6.5.1.2 | 0.00032 | - |
pH and temperature not specified in the publication | Escherichia coli | 5'-deoxy-2-[(trans-4-methylcyclohexyl)oxy]adenosine | |
6.5.1.2 | 0.00037 | - |
pH and temperature not specified in the publication | Escherichia coli | 2-(cyclopentyloxy)-5'-deoxyadenosine | |
6.5.1.2 | 0.00037 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 5'-deoxy-5'-fluoro-2-[[1-(hydroxymethyl)cyclopropyl]methoxy]adenosine | |
6.5.1.2 | 0.00038 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 2-(cyclopentylsulfanyl)adenosine | |
6.5.1.2 | 0.0004 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 5'-deoxy-5'-fluoro-2-[[1-(hydroxymethyl)cyclopropyl]methoxy]adenosine | |
6.5.1.2 | 0.0004 | - |
pH and temperature not specified in the publication | Haemophilus influenzae | 2-[(decahydronaphthalen-2-yl)oxy]adenosine | |
6.5.1.2 | 0.00043 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 2-(cyclopentyloxy)adenosine | |
6.5.1.2 | 0.00044 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 2-(cyclopentylsulfanyl)adenosine | |
6.5.1.2 | 0.00051 | - |
pH and temperature not specified in the publication | Haemophilus influenzae | 2-(butylsulfanyl)adenosine | |
6.5.1.2 | 0.00051 | - |
pH and temperature not specified in the publication | Haemophilus influenzae | 2-(cyclopentyloxy)adenosine | |
6.5.1.2 | 0.00087 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 5'-deoxy-5'-fluoro-2-[(1,3-thiazol-2-yl)methoxy]adenosine | |
6.5.1.2 | 0.00091 | - |
pH and temperature not specified in the publication | Staphylococcus aureus | 5'-deoxy-5'-fluoro-2-[(1,3-thiazol-2-yl)methoxy]adenosine | |
6.5.1.2 | 0.00127 | - |
pH and temperature not specified in the publication | Escherichia coli | 2-(butylsulfanyl)adenosine | |
6.5.1.2 | 0.0015 | - |
pH and temperature not specified in the publication | Escherichia coli | (3aR,5R,6R,6aS)-5-[6-amino-2-(methylsulfanyl)-9H-purin-9-yl]-6-hydroxy-2-sulfanyltetrahydro-2H-2lambda-5-furo[2,3-d][1,3,2]dioxaphosphol-2-one | |
6.5.1.2 | 0.0017 | - |
pH and temperature not specified in the publication | Haemophilus influenzae | 5'-deoxy-2-[(tricyclo[3.3.1.1~3,7~]decan-2-yl)methoxy]adenosine | |
6.5.1.2 | 0.00267 | - |
pH and temperature not specified in the publication | Streptococcus pneumoniae | 5'-deoxy-2-phenoxyadenosine | |
6.5.1.2 | 0.016 | - |
pH and temperature not specified in the publication | Mycobacterium tuberculosis | (2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl dihydrogen phosphate | |
6.5.1.2 | 0.073 | - |
pH and temperature not specified in the publication | Mycobacterium tuberculosis | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | |
6.5.1.2 | 0.12 | - |
pH and temperature not specified in the publication | Escherichia coli | (2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl dihydrogen phosphate | |
6.5.1.2 | 0.138 | - |
pH and temperature not specified in the publication | Escherichia coli | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium | |
6.5.1.2 | 0.2 | - |
pH and temperature not specified in the publication | Mycobacterium tuberculosis | 3-[[[[(2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]oxy](hydroxy)phosphoryl]carbamoyl]-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridin-1-ium |