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Literature summary extracted from

  • Cannone, G.; Xu, Y.; Beattie, T.; Bell, S.; Spagnolo, L.
    The architecture of an Okazaki fragment-processing holoenzyme from the archaeon Sulfolobus solfataricus (2015), Biochem. J., 465, 239-245 .
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
6.5.1.1 proliferating cell nuclear antigen
-
 Saccharolobus solfataricus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.5.1.1 expressed in Escherichia coli Rosetta (DE3) cells Saccharolobus solfataricus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.5.1.1 ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m Saccharolobus solfataricus
-
 (deoxyribonucleotide)n+m + AMP + diphosphate
-
 ?
6.5.1.1 ATP + [DNA ligase]-L-lysine Saccharolobus solfataricus
-
 [DNA ligase]-N6-(5'-adenylyl)-L-lysine + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.5.1.1 Saccharolobus solfataricus Q980T8
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.5.1.1 HisTrap column chromatography, and Superose 10/300 gel filtration Saccharolobus solfataricus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.5.1.1 ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m
-
 Saccharolobus solfataricus (deoxyribonucleotide)n+m + AMP + diphosphate
-
 ?
6.5.1.1 ATP + [DNA ligase]-L-lysine
-
 Saccharolobus solfataricus [DNA ligase]-N6-(5'-adenylyl)-L-lysine + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.5.1.1 ATP-dependent DNA ligase 1
-
 Saccharolobus solfataricus
6.5.1.1 LIG1
-
 Saccharolobus solfataricus
6.5.1.1 ligase 1
-
 Saccharolobus solfataricus