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Literature summary extracted from

  • Sharma, R.; Singhal, S.; Cheng, J.; Yang, Y.; Sharma, A.; Zimniak, P.; Awasthi, S.; Awasthi, Y.
    RLIP76 is the major ATP-dependent transporter of glutathione-conjugates and doxorubicin in human erythrocytes (2001), Arch. Biochem. Biophys., 391, 171-179 .
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.6.2.3 plasma membrane
-
 Homo sapiens 5886
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.6.2.3 ATP + H2O + glutathione-S-conjugate[side 1] Homo sapiens
-
 ADP + phosphate + glutathione-S-conjugate[side 2]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.6.2.3 Homo sapiens Q15311
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.6.2.3 erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.6.2.3 ATP + H2O + 4-hydroxynonenal-glutathione[side 1]
-
 Homo sapiens ADP + phosphate + 4-hydroxynonenal-glutathione[side 2]
-
 ?
7.6.2.3 ATP + H2O + doxorubicin[side 1] best substrate Homo sapiens ADP + phosphate + doxorubicin[side 2]
-
 ?
7.6.2.3 ATP + H2O + glutathione-S-conjugate[side 1]
-
 Homo sapiens ADP + phosphate + glutathione-S-conjugate[side 2]
-
 ?
7.6.2.3 ATP + H2O + leukotriene C4[side 1] worst substrate Homo sapiens ADP + phosphate + leukotriene C4[side 2]
-
 ?
7.6.2.3 ATP + H2O + S-(2,4-dinitrophenyl)glutathione[side 1] second best substrate Homo sapiens ADP + phosphate + S-(2,4-dinitrophenyl)glutathione[side 2]
-
 ?

Subunits

EC Number Subunits Comment Organism
7.6.2.3 ? x * 95000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
7.6.2.3 RLIP76
-
 Homo sapiens