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Literature summary extracted from
- Distribution of 1-aminocyclopropane-1-carboxylate deaminase and d-cysteine desulfhydrase genes among type species of the genus Methylobacterium (2018), Antonie van Leeuwenhoek, 111, 1723-1734 .
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.5.99.7 | gene acdS, DNA and amino acid sequence determination and analysis, genotyping and phylogenetic analysis | Methylobacterium goesingense |
| 3.5.99.7 | gene acdS, DNA and amino acid sequence determination and analysis, genotyping and phylogenetic analysis | Methylobacterium gregans |
| 3.5.99.7 | gene acdS, DNA and amino acid sequence determination and analysis, genotyping and phylogenetic analysis | Methylobacterium longum |
| 3.5.99.7 | gene acdS, DNA and amino acid sequence determination and analysis, genotyping and phylogenetic analysis | Methylobacterium marchantiae |
| 3.5.99.7 | gene acdS, DNA and amino acid sequence determination and analysis, genotyping and phylogenetic analysis | Methylobacterium mesophilicum |
| 3.5.99.7 | gene acdS, DNA and amino acid sequence determination and analysis, genotyping and phylogenetic analysis | Methylobacterium brachiatum |
| 3.5.99.7 | gene acdS, DNA and amino acid sequence determination and analysis, genotyping and phylogenetic analysis | Methylobacterium fujisawaense |
| 3.5.99.7 | gene acdS, DNA and amino acid sequence determination and analysis, genotyping and phylogenetic analysis | Methylobacterium tardum |
| 3.5.99.7 | gene acdS, DNA and amino acid sequence determination and analysis, genotyping and phylogenetic analysis | Methylobacterium gnaphalii |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.4.1.15 | 0.46 | - |
D-cysteine | pH 7.4, 30°C | Methylorubrum extorquens |  |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.4.1.15 | 72000 | - |
PAGE | Methylorubrum extorquens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.99.7 | Methylobacterium brachiatum | A0A346M1A9 | - |
- |
| 3.5.99.7 | Methylobacterium brachiatum B0021 | A0A346M1A9 | - |
- |
| 3.5.99.7 | Methylobacterium fujisawaense | A0A346M1B0 | - |
- |
| 3.5.99.7 | Methylobacterium fujisawaense 0-31 | A0A346M1B0 | - |
- |
| 3.5.99.7 | Methylobacterium gnaphalii | A0A512JJT7 | - |
- |
| 3.5.99.7 | Methylobacterium goesingense | A0A2H4NI51 | - |
- |
| 3.5.99.7 | Methylobacterium goesingense iEII3 | A0A2H4NI51 | - |
- |
| 3.5.99.7 | Methylobacterium gregans | A0A2H4NI69 | - |
- |
| 3.5.99.7 | Methylobacterium gregans 002-074 | A0A2H4NI69 | - |
- |
| 3.5.99.7 | Methylobacterium longum | A0A2H4NI68 | - |
- |
| 3.5.99.7 | Methylobacterium longum 440 | A0A2H4NI68 | - |
- |
| 3.5.99.7 | Methylobacterium marchantiae | A0A2H4NI67 | - |
- |
| 3.5.99.7 | Methylobacterium marchantiae JT1 | A0A2H4NI67 | - |
- |
| 3.5.99.7 | Methylobacterium mesophilicum | A0A2H4NI93 | - |
- |
| 3.5.99.7 | Methylobacterium mesophilicum A47 | A0A2H4NI93 | - |
- |
| 3.5.99.7 | Methylobacterium tardum | A0A346M1B1 | - |
- |
| 3.5.99.7 | Methylobacterium tardum RB677 | A0A346M1B1 | - |
- |
| 4.4.1.15 | Methylorubrum extorquens | C5AQP6 | - |
- |
| 4.4.1.15 | Methylorubrum extorquens DSM 1338 | C5AQP6 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.4.1.15 | D-cysteine + H2O | - |
Methylorubrum extorquens | sulfide + NH3 + pyruvate | - |
? | |
| 4.4.1.15 | D-cysteine + H2O | - |
Methylorubrum extorquens DSM 1338 | sulfide + NH3 + pyruvate | - |
? | |
| 4.4.1.15 | additional information | no substrate: L-cysteine, 1-aminocyclopropane-1-carboxylate | Methylorubrum extorquens | ? | - |
? | |
| 4.4.1.15 | additional information | no substrate: L-cysteine, 1-aminocyclopropane-1-carboxylate | Methylorubrum extorquens DSM 1338 | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.5.99.7 | ACC deaminase | - |
Methylobacterium goesingense |
| 3.5.99.7 | ACC deaminase | - |
Methylobacterium gregans |
| 3.5.99.7 | ACC deaminase | - |
Methylobacterium longum |
| 3.5.99.7 | ACC deaminase | - |
Methylobacterium marchantiae |
| 3.5.99.7 | ACC deaminase | - |
Methylobacterium mesophilicum |
| 3.5.99.7 | ACC deaminase | - |
Methylobacterium brachiatum |
| 3.5.99.7 | ACC deaminase | - |
Methylobacterium fujisawaense |
| 3.5.99.7 | ACC deaminase | - |
Methylobacterium tardum |
| 3.5.99.7 | ACC deaminase | - |
Methylobacterium gnaphalii |
| 3.5.99.7 | AcdS | - |
Methylobacterium goesingense |
| 3.5.99.7 | AcdS | - |
Methylobacterium gregans |
| 3.5.99.7 | AcdS | - |
Methylobacterium longum |
| 3.5.99.7 | AcdS | - |
Methylobacterium marchantiae |
| 3.5.99.7 | AcdS | - |
Methylobacterium mesophilicum |
| 3.5.99.7 | AcdS | - |
Methylobacterium brachiatum |
| 3.5.99.7 | AcdS | - |
Methylobacterium fujisawaense |
| 3.5.99.7 | AcdS | - |
Methylobacterium tardum |
| 3.5.99.7 | aspB | - |
Methylobacterium gnaphalii |
| 4.4.1.15 | DCyD | - |
Methylorubrum extorquens |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 4.4.1.15 | 65 | - |
- |
Methylorubrum extorquens |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.4.1.15 | 5.2 | - |
D-cysteine | pH 7.4, 30°C | Methylorubrum extorquens | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.4.1.15 | 9 | - |
- |
Methylorubrum extorquens |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.5.99.7 | evolution | distribution of 1-aminocyclopropane-1-carboxylate deaminase genes among type species of the genus Methylobacterium, overview | Methylobacterium goesingense |
| 3.5.99.7 | evolution | distribution of 1-aminocyclopropane-1-carboxylate deaminase genes among type species of the genus Methylobacterium, overview | Methylobacterium gregans |
| 3.5.99.7 | evolution | distribution of 1-aminocyclopropane-1-carboxylate deaminase genes among type species of the genus Methylobacterium, overview | Methylobacterium longum |
| 3.5.99.7 | evolution | distribution of 1-aminocyclopropane-1-carboxylate deaminase genes among type species of the genus Methylobacterium, overview | Methylobacterium marchantiae |
| 3.5.99.7 | evolution | distribution of 1-aminocyclopropane-1-carboxylate deaminase genes among type species of the genus Methylobacterium, overview | Methylobacterium mesophilicum |
| 3.5.99.7 | evolution | distribution of 1-aminocyclopropane-1-carboxylate deaminase genes among type species of the genus Methylobacterium, overview | Methylobacterium brachiatum |
| 3.5.99.7 | evolution | distribution of 1-aminocyclopropane-1-carboxylate deaminase genes among type species of the genus Methylobacterium, overview | Methylobacterium fujisawaense |
| 3.5.99.7 | evolution | distribution of 1-aminocyclopropane-1-carboxylate deaminase genes among type species of the genus Methylobacterium, overview | Methylobacterium tardum |
| 3.5.99.7 | evolution | distribution of 1-aminocyclopropane-1-carboxylate deaminase genes among type species of the genus Methylobacterium, overview | Methylobacterium gnaphalii |
kcat/KM [mM/s]
| EC Number | kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.4.1.15 | 11.3 | - |
D-cysteine | pH 7.4, 30°C | Methylorubrum extorquens | |
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Release 2023.1 (January 2023)
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