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Literature summary extracted from

  • Pan, J.; Solbiati, J.; Ramamoorthy, G.; Hillerich, B.; Seidel, R.; Cronan, J.; Almo, S.; Poulter, C.
    Biosynthesis of squalene from farnesyl diphosphate in Bacteria Three steps catalyzed by three enzymes (2015), ACS Cent. Sci., 1, 77-82 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.4.99.17 squalene Streptomyces coelicolor
-
 hop-22(29)-ene
-
 ?
5.4.99.17 squalene Streptomyces coelicolor A3(2)
-
 hop-22(29)-ene
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.4.99.17 Streptomyces coelicolor
-
-
-
5.4.99.17 Streptomyces coelicolor A3(2)
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.99.17 additional information hydroxysqualene is a poor substrate Streptomyces coelicolor ?
-
 ?
5.4.99.17 additional information hydroxysqualene is a poor substrate Streptomyces coelicolor A3(2) ?
-
 ?
5.4.99.17 squalene
-
 Streptomyces coelicolor hop-22(29)-ene
-
 ?
5.4.99.17 squalene
-
 Streptomyces coelicolor A3(2) hop-22(29)-ene
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.4.99.17 SHC
-
 Streptomyces coelicolor
5.4.99.17 SQ-hopene cyclase
-
 Streptomyces coelicolor