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Literature summary extracted from

  • Chen, E.H.; Hou, Q.L.; Wei, D.D.; Dou, W.; Liu, Z.; Yang, P.J.; Smagghe, G.; Wang, J.J.
    Tyrosine hydroxylase coordinates larval-pupal tanning and immunity in oriental fruit fly (Bactrocera dorsalis) (2018), Pest Manag. Sci., 74, 569-578 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.16.2 3-iodo-L-tyrosine
-
 Bactrocera dorsalis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.16.2 65300
-
 calculated from amino acid sequence Bactrocera dorsalis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.16.2 L-tyrosine + tetrahydrobiopterin + O2 Bactrocera dorsalis
-
 L-dopa + 4a-hydroxytetrahydrobiopterin + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.16.2 Bactrocera dorsalis
-
 oriental fruit fly
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.16.2 epidermis
-
 Bactrocera dorsalis
-
1.14.16.2 fat body
-
 Bactrocera dorsalis
-
1.14.16.2 larva
-
 Bactrocera dorsalis
-
1.14.16.2 pupa
-
 Bactrocera dorsalis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.16.2 L-tyrosine + tetrahydrobiopterin + O2
-
 Bactrocera dorsalis L-dopa + 4a-hydroxytetrahydrobiopterin + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
1.14.16.2 More x * 65300, calculated from amino acid sequence Bactrocera dorsalis

Synonyms

EC Number Synonyms Comment Organism
1.14.16.2 tyrosine hydroxylase
-
 Bactrocera dorsalis

pI Value

EC Number Organism Comment pI Value Maximum pI Value
1.14.16.2 Bactrocera dorsalis calculated from amino acid sequence
-
 5.4

Expression

EC Number Organism Comment Expression
1.14.16.2 Bactrocera dorsalis the enzyme is expressed in the epidermis during development or in the fat body after Beauveria bassiana infection up

General Information

EC Number General Information Comment Organism
1.14.16.2 malfunction enzyme suppression impairs Bactrocera dorsalis immunity Bactrocera dorsalis
1.14.16.2 physiological function tyrosine hydroxylase coordinates larval-pupal tanning and immunity in Bactrocera dorsalis Bactrocera dorsalis