Literature summary extracted from

Leitao, J.; Esteves da Silva, J.
Firefly luciferase inhibition (2010), J. Photochem. Photobiol. B, 101, 1-8 .

Inhibitors

EC Number	Inhibitors	Comment	Organism
6.2.1.52	2-(4-benzoylphenyl)thiazole-4-carboxylic acid	competitive inhibitor	Photinus pyralis
6.2.1.52	2-benzothiazole sulfonic acid	competitive inhibitor	Photinus pyralis
6.2.1.52	2-Cyano-4-hydroxybenzothiazole	-	Photinus pyralis
6.2.1.52	2-Cyano-5-methoxybenzothiazole	-	Photinus pyralis
6.2.1.52	2-Cyano-6-chlorobenzothiazole	-	Photinus pyralis
6.2.1.52	2-cyano-6-hydroxybenzothiazole	-	Photinus pyralis
6.2.1.52	2-cyano-6-methoxybenzothiazole	-	Photinus pyralis
6.2.1.52	5'-O-[(N-dehydroluciferyl)-sulfamoyl]-adenosine	-	Photinus pyralis
6.2.1.52	5,5-dimethylluciferin	-	Photinus pyralis
6.2.1.52	5-(cis)-methylluciferin	-	Photinus pyralis
6.2.1.52	5-(trans)-methylluciferin	-	Photinus pyralis
6.2.1.52	6'-Acetylaminoluciferin	-	Photinus pyralis
6.2.1.52	6'-Aminoluciferin	-	Photinus pyralis
6.2.1.52	6'-Chloroluciferin	-	Photinus pyralis
6.2.1.52	6'-deshydroxyluciferin	-	Photinus pyralis
6.2.1.52	6'-Ethoxyluciferin	-	Photinus pyralis
6.2.1.52	6'-Methoxyluciferin	-	Photinus pyralis
6.2.1.52	6'-methylluciferin	-	Photinus pyralis
6.2.1.52	6-(4-hydoxyphenyl)hexanoic acid	competitive inhibitor	Photinus pyralis
6.2.1.52	6-Hydroxybenzothiazole	-	Photinus pyralis
6.2.1.52	6-methoxydehydroluciferin	-	Photinus pyralis
6.2.1.52	Benzothiazole	-	Photinus pyralis
6.2.1.52	D-naphthylluciferin	-	Photinus pyralis
6.2.1.52	D-quinolylluciferin	-	Photinus pyralis
6.2.1.52	Decarboxyluciferin	-	Photinus pyralis
6.2.1.52	dehydroluciferyl-CoA	-	Photinus pyralis
6.2.1.52	ethyl 2-benzothiazolesulfonate	competitive inhibitor towards luciferin, non-competitive inhibitor towards ATP	Photinus pyralis
6.2.1.52	Homoluciferin	-	Photinus pyralis
6.2.1.52	methyl 4-nitrobenzenesulfonate	-	Photinus pyralis
6.2.1.52	oxyluciferin	competitive inhibitor	Photinus pyralis

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
6.2.1.52	ATP + L-firefly luciferin + CoA	Photinus pyralis	-	AMP + diphosphate + L-firefly luciferyl-CoA	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.2.1.52	Photinus pyralis	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.2.1.52	ATP + L-firefly luciferin + CoA	-	Photinus pyralis	AMP + diphosphate + L-firefly luciferyl-CoA	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
6.2.1.52	long-chain fattyacyl-CoA synthetase	-	Photinus pyralis
6.2.1.52	Luc	-	Photinus pyralis