EC Number | Crystallization (Comment) | Organism |
---|---|---|
2.7.7.7 | crystals are grown at 20°C according to the hanging-drop vapor-diffusion method. The N-terminal (1-300) domain structure of the large subunit was determined by X-ray crystallography, although about 50 N-terminal residues are disordered. The determined structure consists of nine alpha helices and three beta strands. The DNA-binding ability of the domain by is identified by SPR measurement. The N-terminal (1-100) region plays crucial roles in the folding of the large subunit dimer by connecting the about 50 N-terminal residues with their own catalytic region (792-1163) | Pyrococcus horikoshii |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.7.7 | 420000 | - |
- |
Pyrococcus horikoshii |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.7.7 | Pyrococcus horikoshii | O57863 and O57861 | O57863: DNA polymerase II small subunit, gene name polB, ordered locus name: PH0123, O57861: DNA polymerase II large subunit, gene name polC, ordered locus name: PH0121 | - |
2.7.7.7 | Pyrococcus horikoshii OT-3 | O57863 and O57861 | O57863: DNA polymerase II small subunit, gene name polB, ordered locus name: PH0123, O57861: DNA polymerase II large subunit, gene name polC, ordered locus name: PH0121 | - |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.7.7.7 | heterotetramer | heterotetramer consisting of two small subunits (locus name: PH0123) and two large subunits (locus name: PH0121). The large subunits is the catalytic subunit of DNA polymerase, while the small subunits is the catalytic subunit of Mre11-like 3'-5' exonuclease | Pyrococcus horikoshii |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.7.7 | hoPolD | - |
Pyrococcus horikoshii |
2.7.7.7 | PH0121 | locus name of DNA polymerase II large subunit | Pyrococcus horikoshii |
2.7.7.7 | PH0123 | locus name of DNA polymerase II small subunit | Pyrococcus horikoshii |
2.7.7.7 | polD | - |
Pyrococcus horikoshii |