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Literature summary extracted from

  • Eutsey, R.; Wang, G.; Maier, R.J.
    Role of a MutY DNA glycosylase in combating oxidative DNA damage in Helicobacter pylori (2007), DNA Repair, 6, 19-26 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.2.2.31 expressed in Escherichia coli BL21 Rosetta pLys and PR70 cells Helicobacter pylori

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.2.31 DNA containing a 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine mismatch + H2O Helicobacter pylori
-
 ?
-
 ?
3.2.2.31 additional information Helicobacter pylori the enzyme shows no activity with DNA containing a guanine:adenine mismatch ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.2.31 Helicobacter pylori
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.2.31 Ni-NTA column chromatography Helicobacter pylori

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.2.31 DNA containing a 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine mismatch + H2O
-
 Helicobacter pylori ?
-
 ?
3.2.2.31 additional information the enzyme shows no activity with DNA containing a guanine:adenine mismatch Helicobacter pylori ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.2.31 mutY
-
 Helicobacter pylori

General Information

EC Number General Information Comment Organism
3.2.2.31 physiological function the enzyme plays a significant role in oxidative DNA damage repair in vivo Helicobacter pylori